(n.) The Altar; a southern constellation, south of the tail of the Scorpion.
(n.) A name of the great blue and yellow macaw (Ara ararauna), native of South America.
Example Sentences:
(1) The antitumor effect of C18PCA and Ara-C was investigated against the P388 ascites tumor in BDF1 mice.
(2) However, the walker 256 intramuscular tumor did not respond to ARA-C capsules implanted, and the animals died at the same rate as the controls, with large ulcerated tumor masses and some metastasis.
(3) 5 heavily pretreated patients with chronic lymphocytic leukaemia or non-Hodgkin lymphoma resistant to alkylating agents were treated with low-dose cytosine arabinoside (ARA-C).
(4) Rat liver microsomes demethylated ara-DMAP much more rapidly than human liver microsomes did.
(5) Enhanced ara-CTP formation was observed in cells lacking cytidine deaminase (L1 210 and HL60), indicating that 3-deazauridine inhibition of deoxycytidylate deaminase may be important in this drug interaction.
(6) This study demonstrates the mutagenic properties of F-ara-A and ara-A and provides evidence for mechanisms by which the arabinosyl nucleosides induce mutation.
(7) Patient cells had low rates for ara-C transport as compared with human and murine experimental cells and correspondingly low binding capacities for the nucleoside transport inhibitor, nitrobenzylmercaptopurine riboside (NBMPR).
(8) The inhibitions by ara-GTP and 9-beta-D-arabinofuranosyladenine 5'-triphosphate were due to competition or partial competition 5'-triphosphate were due to competition or partial competition with deoxynucleoside triphosphate with the same base.
(9) The incorporation of F-ara-A monophosphate into mRNA resulted in premature termination of the RNA transcript and impaired its functioning as a template for protein synthesis.
(10) Pharmacological studies of 5'-esters of 1 beta-D-arabinofuranosylcytosine (ara-C) were performed in three species (mouse, pig, and man).
(11) These results provide some support for the view that cell kill may not be the only basis for the chemotherapeutic effectiveness of ara-C.
(12) Accelerating test at a constant temperature indicates that liposome-entrapped Ara-A has certain chemical stability.
(13) Although statistically significant, the effect of DP on ara-CTP retention in AML blasts was much less pronounced than that previously observed in L5178Y leukemia.
(14) He was treated with the combination chemotherapy of BACOD with high dose ara-C or methotrexate followed by 4 doses of autologous LAK cell infusion resulting in no significant response.
(15) Regardless whether cyclo-C or ara-C is injected, the plasma decay curve of the resultant ara-C is biphasic, with calculated half-lives of 40 min and 2-2.5 hr.
(16) Serial measurements of DNA synthesis and net intracellular ara-C metabolism demonstrated marked increases in both determinants in day 8 residual tumor when compared with the pretreatment cells for newly diagnosed adults achieving complete remission but not for TST-refractory patients.
(17) Determination of the intracellular content of the active metabolite of ara-C, ara-CTP, excluded more prolonged retention of the drug as the basis for potentiation of cytotoxicity.
(18) With the aim of improving the treatment of AML patients the activities of selected nucleoside metabolizing enzymes of possible implication for the initial metabolism of Ara-C have been studied in leukemic and normal cells.
(19) Ara-C. We conclude that prophylactic CNS therapy may cause cognitive dysfunctions.
(20) This was possible because the Ara test, for volatile compounds (such as vinyl bromide), did not require the use of special vaporization techniques, which are difficult to evaluate quantitatively for mutagenic activity.