(a.) To lower or depress; to throw or cast down; as, to abase the eye.
(a.) To cast down or reduce low or lower, as in rank, office, condition in life, or estimation of worthiness; to depress; to humble; to degrade.
Example Sentences:
(1) And then, proving that in the celebrity world of self-abasement there really is no such thing as "bottoming out", Shane started tweeting Ping Pong, otherwise known as Elizabeth Hurley's parrot Why has Australia not staged an intervention?
(2) These studies establish that the exocyclic ring of the 1,N2-propanodeoxyguanosine adduct fits into the cavity generated by the abasic site.
(3) Covalently closed circular DNA containing a synthetic analog of an abasic site at a unique position was used as a substrate to study DNA repair.
(4) In this study, we present structural and dynamic properties of duplex oligodeoxynucleotides containing G, C and T opposite a model abasic site studied by one and two-dimensional nuclear magnetic resonance spectroscopy.
(5) By this assay, we first identified the formation of C-4'-hydroxy abasic sites in calf thymus DNA by neocarzinostatin.
(6) Abasic lesions in the template had relatively little effect on the polymerase incorporation reaction at sites proximal to the lesion.
(7) Facebook Twitter Pinterest A composite handout of CCTV pictures from the Metropolitan police showing British teenagers (L-R) Kadiza Sultana, Amira Abase and Shamima Begum passing through security barriers at Gatwick Airport en route to Syria.
(8) Proton and phosphorus NMR studies are reported for two complementary nonanucleotide duplexes containing acyclic abasic sites.
(9) Shamima Begum, 15, Amira Abase, 15, and Kadiza Sultana, 16, left their homes in east London last month to join the extremist group.
(10) However, incorporation opposite an abasic site was undetectable relative to that which occurred opposite a normal template nucleotide.
(11) But with the People's Daily writing that progress had only been possible because of David Cameron's admission that he had mishandled Tibet (where, since 2009, 100 monks and nuns have set fire to themselves in protest against Chinese rule), Britain's abasement was complete.
(12) Shamima Begum, 15, Kadiza Sultana, 16, and Amira Abase, 15, fled in February from Britain after deceiving their parents and siblings.
(13) The long pilgrimage of pregnancy with its wonders and abasements, the apotheosis of childbirth, the sacking and slow rebuilding of every last corner of my private world that motherhood has entailed – all unmentioned, wilfully or casually forgotten as time has passed.
(14) Before and after training they were low in need for order, endurance, abasement, and deference and high in need for autonomy and aggression.
(15) All the sequenced mutants correspond to single base-pair substitutions targeted at the abasic site.
(16) These results indicate that dTMP, and not dAMP, was mainly incorporated into the sites opposite to the abasic site analogue, and that incorrect deoxynucleotides were incorporated in the position adjacent to the abasic site analogue.
(17) Our results in human cells contrast markedly with those published previously for the mutational specificity of AP sites in Escherichia coli, in which a large majority of the mutants resulted from insertion of an A opposite the abasic site.
(18) The repair-related DNA synthesis was localized within 3 or 4 nucleotides surrounding the abasic site.
(19) The enzyme is able to incorporate nucleotides efficiently opposite the abasic template lesion and to continue DNA synthesis.
(20) The Met statement did appear to show some contrition stating: “With the benefit of hindsight, we acknowledge that the letters could have been delivered direct to the parents.” The disappearance of the 15-year-old girl in December led to a counter-terrorism investigation that saw Begum, Sultana and Abase identified as friends of the missing girl and being spoken to by detectives.
Deprecate
Definition:
(v. t.) To pray against, as an evil; to seek to avert by prayer; to desire the removal of; to seek deliverance from; to express deep regret for; to disapprove of strongly.
Example Sentences:
(1) "I cannot tell you how I should deprecate anything leading to the publication of these letters," she clucked to her publisher.
(2) Low degrees of role interference is likewise disconcerting to persons but in the absence of an external target for aggression may lead to self deprecation and ultimately suicide.
(3) Despite the sometimes self-deprecating shtick – in sharp contrast to Putin's self-mythologising antics – there remains disquiet about what Navalny really represents, behind the caustic put-downs and cool persona.
(4) Stone’s depiction of himself in his book tallies well with Bilton’s: self-deprecating, a peacemaker, but also someone who gets things done.
(5) Her newspaper profiles over the years are peppered with self-deprecating references to her sporting ruthlessness: her constant mentions of her selfishness and egotism; her win-at-all-costs, only-gold-medals-matter mentality; or the time she flung her helmet at her boyfriend in frustration after losing a race.
(6) This was a galaxy-spanning utopia whose name was chosen for its self-deprecating modesty, rather than something grandiose like the Federation or the Empire.
(7) He reads out deprecating messages: "Loving the show, even the little mistakes," "Sounds like you're on some ITV sitcom in the 80s."
(8) But this was still very much hero worship, northern-style: the 100 or so Werder Bremen fans stood in orderly rows in the Bremen airport arrivals hall in early September, strictly behind the barrier, of course, and many of them carried smiles that were equal parts genuine, childlike excitement and self-deprecating mocking of their own genuine, childlike excitement, a way to cope with the sense of wonderment: are we really here?
(9) Johnson is the master-builder of that image, deflecting every lie, every gaffe, dishonesty and U-turn with some self-deprecating metaphor: calling his feigned indecision “veering all over the place like a shopping trolley” was worth a world of worthy platitudes.
(10) But he uses what he learned from Rantzen: she taught him, he said somewhat self-deprecatingly, the “tricks of trash journalism.
(11) Whether she's pitching her own feminist rap video or reading us her cautionary rewrite of The Ugly Duckling, her self-deprecating anecdotal style invites us to laugh at her middle-class embarrassment while she slips some important truths past.
(12) Like Diana, Prince Philip has tended to be self-deprecating on the subject of his education ("I am one of those ignorant bastards who never went to a university").
(13) The use of AAS as ergogenic drugs must be deprecated because of their marginal effects, the risks of side effects and the unsporting, unethical aspects.
(14) Now the self-deprecating circular is fashionable, and we've had a few this year.
(15) Linked with a self-deprecating acknowledgement that our own fallibility and imperfection is likely to be exposed, we at least introduce a modicum of suspicion to our consumption of dominant media and political narratives.
(16) When the intensity of the noise increased to 70 and 75dB SPL, speech discrimination scores by both devices deprecated together with consistent difference (P less than 0.01).
(17) Cat videos aside, there’s an unspoken war going on – who can be the funniest, who can be the cleverest, who has the most amusingly self-deprecating hangover.
(18) For all the shared self-deprecating glee, nobody really knows what to expect.
(19) Briers, always the most modest and self-deprecating of actors, and the sweetest of men, relished the review, happy to claim a place in the light comedians' gallery of his knighted idols Charles Hawtrey, Gerald du Maurier and Noël Coward.
(20) Polypharmacy is deprecated and either an aminoglycoside or a cephalosporin forms the mainstay of therapy.