(1) The algorithm is used for irradiation planning for the Soviet ANET-B unit with 252Cf sources.
(2) Devices and radiation-technical equipment for adaptation of the ANET-B apparatus for irradiation of neurosurgical patients are described.
(3) The total dose in point A was 60 isoGy in either case given in 3 fractions at 28 days using the after-loading units "ANET" (neutrons) and "AGAT V" (gamma).
(4) The first experience in using CT-stereotaxic neutron brachytherapy with californium sources on the ANET-B apparatus for the treatment of 6 patients with malignant glial tumors of the brain is dwelt on.
(5) Radiation dose levels for the medical staff are 10-15 times lower for the ANET-W apparatus than those for 252Cf sources administered by the manual series system but 10 times higher than those for the AGAT-W gamma-apparatus.
(6) Comprehensive radiobiological studies of the relative biological and genetic efficacy (RBE and RGE) of powerful 252Cf radiation (the ANET-B unit) were conducted using research tools of various radiosensitivity (bacteria, Drosophila, Chinese hamster cells, murine thymocytes, human and murine bone marrow stem cells, human peripheral blood lymphocytes, Lewis lung carcinoma cells).
(7) Topometric investigations for each patient were performed 4 times: before the first session of fractionated intracavitary irradiation with high activity 252Cf sources using the ANET-B unit and after each session of irradiation.
(8) The paper is concerned with the results of therapy of 35 patients with Stage I-II uterine body cancer with the method of combined modality radiotherapy using neutron radiation of high energy 252Cf sources on the ANET-B unit with a system of automatic remote-control delivery of sources for intracavitary irradiation.
(9) Endometrial cancer patients received intracavitary irradiation from the Anet-B installation using a high-energy 252-Cf source.
(10) Radiosurgical implantation of sources with increased 252Cf content emitting mixed neutron + gamma-radiation was accomplished by means of an ANET-B apparatus by the afterloading method.
(11) To provide neutron beam therapy they employed contact apparatuses and flexible assemblies of 252Cf sources and the ANET-B neutron therapeutic unit.
(12) The Soviet ANET-W intracavitary neutron therapy apparatus is charged with 252Cf sources, the total mass of the radionuclide being 2100 micrograms.
(13) The design, blocking system and emergency reset of the sources provide for safe work on the ANET-W apparatus.