What's the difference between abnormal and hyperchromatism?
Abnormal
Definition:
(a.) Not conformed to rule or system; deviating from the type; anomalous; irregular.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(3) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
(4) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(5) Among a family of 8 children, 4 presented typical clinical and biological abnormalities related to mannosidosis.
(6) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(7) The secondary leukemia that occurred in these patients could be distinguished from the secondary leukemia that occurs after treatment with alkylating agents by the following: a shorter latency period; a predominance of monocytic or myelomonocytic features; and frequent cytogenetic abnormalities involving 11q23.
(8) Immediate postexercise two-dimensional echocardiography demonstrated exercise-induced changes in 8 (47%) patients (2 with normal and 6 with abnormal results from rest studies).
(9) The psychiatric experts classified 11 of the perpetrators as "normal," 3 as abnormal, and 2 as psychotic.
(10) Erythrocyte membrane choline transport is abnormally high in chronic renal failure.
(11) Although the longest period required for resolving weakness was three days, the MRI, the CT and the electroencephalogram revealed no significant abnormality.
(12) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(13) Muscle wasting in MYD may be explained by these abnormalities as well.
(14) Associated renal and other abnormalities were common.
(15) Once the normal variations are mastered, appreciation of retinal, choroidal, optic nerve, and vitreal abnormalities is possible.
(16) Eight other children (20%) had normal or borderline elevation of CPK-MB fraction and EKG abnormalities combined with abnormal echocardiograms or radionuclide angiograms, and were considered to have sustained cardiac concussion.
(17) Several investigators have attempted to correlate chromosomal abnormalities with Cornelia de Lange Syndrome (CLS), but none of them have been conclusive.
(18) It is possible that the IgE that linked abnormally with the propofol had specific binding sites for the phenyl nucleus and the isopropyl groups, which are present in propofol and many other drugs.
(19) Of 185 with readable histology, 14.6% were clinically and histologically abnormal; 19.5% were clinically abnormal but histologically normal; and 15.7% were clinically normal and histologically abnormal.
(20) Mice also had a decreased ability to develop delayed-type hypersensitivity reactions while being given cadmium; this abnormality also returned toward normal after withdrawal of cadmium.
Hyperchromatism
Definition:
(n.) The condition of having an unusual intensity of color.
Example Sentences:
(1) Moderately differentiated tumor revealed a wider range of nucleus size, less clustering (coefficient--3.59) and more hyperchromatic (70.1%) and "bare" (49.4%) nuclei and large nucleoli (22.2%).
(2) There were several dilated, distorted tubuli lined with abnormal epithelial cells with large, hyperchromatic nuclei.
(3) The PAS hyperchromaticity of basement membrane material and pericyte loss occurred throughout the retinal vasculature, while while the microaneurysms and complex lesions were limited to the capillaries of the central and paracentral retina.
(4) Light microscopy revealed nests of tumor cells with oval hyperchromatic nuclei.
(5) The nuclei of the tumor cells were slightly hyperchromatic and not bizarre or pleomorphic.
(6) Data which favor the diagnosis of leiomyosarcoma are: (1) spindle-shaped cells with malignant looking nuclei; (2) cells with extremely long, fiber-like cytoplasms and hyperchromatic nuclei; (3) large, anaplastic malignant cells.
(7) These cells have moderately hyperchromatic nuclei with finely granular pattern, which were round or oval, and have tiny nucleoli.
(8) On the basis of clinical observation and with reference to a Chinese and Tibetan medical tradition a reflexological interpretation is suggested for hyperchromatic structures in relation to organic and functional pathologies.
(9) Transrectal FNA of the prostate produced samples that included clusters of malignant cells with crowding and overlapping of hyperchromatic nuclei containing prominent nucleoli and a loss of polarization and cohesion.
(10) The coefficient of clustering was 3.99 whereas the percentage of hyperchromatic and "bare" nuclei and large nucleoli-69.7, 52.1 and 17.4.
(11) Histologically, the tumor was composed of various sized multiple cysts which were completely or incompletely lined by a layer of mucin-producing columnar epithelial cells with moderate nuclear hyperchromatism, and of a papillary pattern in some parts, indicating low grade malignancy.
(12) Some parts of the tumor resembled a vascular lipoma, others contained multivesiculated primitive cells and hyperchromatic multi-nucleated and granular lipoblasts.
(13) The five most valuable signs were "mild koilocytosis," mild dyskeratocytosis," hyperchromatic nuclei, bi- and multinucleation, and cleared cytoplasm.
(14) The HBs displayed single or small aggregates or larger clusters of cells with a high nuclear-cytoplasmic ratio and usually round, hyperchromatic nuclei with single, and occasionally double, prominent nucleoli.
(15) Following radiation and chemotherapy, in addition to increased necrosis and vascular response, a variety of characteristic but nonspecific changes were observed in cell and nuclear morphology with prominent formation of multinucleated giant and monstrous cells, irregular and hyperchromatic nuclei, and severe cytoplasmic degeneration indicating both inhibition of cell division and cell damage.
(16) Two different cell groups were demonstrated in the papulonodular eruptions: large atypical cells with multiple nuclei that were well stained with anti-Tac, but not with Leu 3a, and other cells that possessed prominent hyperchromatic nuclei and which stained well with Leu I and Leu 3a but not with anti-Tac.
(17) Nuclei of acinar cells were hyperchromatic and pleomorphic.
(18) These areas may demonstrate large pleomorphic hyperchromatic nuclei, numerous mitotic figures, and a tendency toward squamous differentiation with many of the neoplastic cells demonstrating individual keratinization.
(19) Microscopically, the tumor was found to consist of a rough fibrous connective tissue stroma with groups of minor monomorphic lymphocyte-like cells and glandular-like cavities that were lined with melanin-containing hyperchromatic rounded and flattened epithelioid cells.
(20) Smears showed moderate cellularity, consisting of moderately to markedly atypical cells with enlarged hyperchromatic nuclei.