(a.) Not conformed to rule or system; deviating from the type; anomalous; irregular.
Example Sentences:
(1) Cancer patients showed abnormally high plasma free tryptophan levels.
(2) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(3) Clonal abnormalities involving chromosomes 3 and 21 were noted in two patients.
(4) Clinical signs of disease developed as early as 15 days after transition to the experimental diets and included impaired vision, decreased response to external stimuli, and abnormal gait.
(5) Among a family of 8 children, 4 presented typical clinical and biological abnormalities related to mannosidosis.
(6) Also we found that the lipid deposition in the glomeruli of patients with Alagille syndrome is related to an abnormal lipid metabolism, which is the consequence of severe cholestasis.
(7) The secondary leukemia that occurred in these patients could be distinguished from the secondary leukemia that occurs after treatment with alkylating agents by the following: a shorter latency period; a predominance of monocytic or myelomonocytic features; and frequent cytogenetic abnormalities involving 11q23.
(8) Immediate postexercise two-dimensional echocardiography demonstrated exercise-induced changes in 8 (47%) patients (2 with normal and 6 with abnormal results from rest studies).
(9) The psychiatric experts classified 11 of the perpetrators as "normal," 3 as abnormal, and 2 as psychotic.
(10) Erythrocyte membrane choline transport is abnormally high in chronic renal failure.
(11) Although the longest period required for resolving weakness was three days, the MRI, the CT and the electroencephalogram revealed no significant abnormality.
(12) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(13) Muscle wasting in MYD may be explained by these abnormalities as well.
(14) Associated renal and other abnormalities were common.
(15) Once the normal variations are mastered, appreciation of retinal, choroidal, optic nerve, and vitreal abnormalities is possible.
(16) Eight other children (20%) had normal or borderline elevation of CPK-MB fraction and EKG abnormalities combined with abnormal echocardiograms or radionuclide angiograms, and were considered to have sustained cardiac concussion.
(17) Several investigators have attempted to correlate chromosomal abnormalities with Cornelia de Lange Syndrome (CLS), but none of them have been conclusive.
(18) It is possible that the IgE that linked abnormally with the propofol had specific binding sites for the phenyl nucleus and the isopropyl groups, which are present in propofol and many other drugs.
(19) Of 185 with readable histology, 14.6% were clinically and histologically abnormal; 19.5% were clinically abnormal but histologically normal; and 15.7% were clinically normal and histologically abnormal.
(20) Mice also had a decreased ability to develop delayed-type hypersensitivity reactions while being given cadmium; this abnormality also returned toward normal after withdrawal of cadmium.
Teratological
Definition:
(a.) Of or pertaining to teratology; as, teratological changes.
Example Sentences:
(1) The importance of precocious development for planning teratological studies is emphasized.
(2) Unlike previous studies with 13-cis-retinoic acid during the pre- and early organogenic stages of development (Hummler et al., Teratology 42:263-272, 1990), no thymic hypo- or aplasia or heart anomalies were observed, which may be attributable to the slightly longer 13-cis retinoic acid treatment period, i.e., GD 10-27.
(3) It seems likely that diaphragmatic hernia is a non-specific consequence of several teratological processes.
(4) The principles of teratology are described, and animal models for research in abnormal ocular development and clinical studies of human teratogens are surveyed.
(5) Functional teratology is quite a new concept in neuroscience.
(6) Dams were killed on Day 19 and the fetuses were assessed for teratologic anomalies.
(7) On the basis of findings published in the literature, morphologic changes seen among the author's patients were classified as anthropologic and teratologic dislocations.
(8) The synthesis of these sciences into the relatively nascent science of reproductive toxicology includes teratology, pharmacology, epidemiology, and occupational and environmental health.
(9) In 1652, a chair of anatomy was created; embryology and teratology, at that time solely morphological sciences, depended on anatomy.
(10) No teratological or abortifacient effects were noted.
(11) The elaboration of the effect of retinoic acid on limb morphogenesis has prompted renewed investigation into the teratology of retinoic acid treatment, with the hope that such analysis might give insight into mechanisms of vertebrate patterning.
(12) The first generation (F0) gilts were bred after 4 months of study; some were killed for teratologic assays at 100 days of gestation (dg), and the others produced an F1 generation of offspring.
(13) The results are discussed with particular reference to the evaluation of teratologic studies on food colouring in general and the various regulation proposals from the National Food Administration.
(14) It also illustrates that selected histochemical studies may be helpful in a teratologic investigation.
(15) Subtle functional disturbances in organisms exposed while immature (behavioral teratology) may be one of the most sensitive indicators of chemical toxicity.
(16) N-Ethyl-N-nitrosourea (ENU) was administered intravenously to pregnant Wistar-albino rats on days 14--21 of gestation in order to study the teratological effects of the carcinogen on the developing brain.
(17) Concerning the applied doses no teratological effect was observed.
(18) The developmental toxicity of acetonitrile and 5 halogenated derivatives was examined with an in vivo teratology screen adapted for use in the Long-Evans rat.
(19) A wealth of literature has become available about lasting functional consequences of perinatal psychotropic drug exposure, having affected brain development in a subtle rather than gross structural way (behavioral teratology or functional neuroteratology).
(20) It is suggested that teratological investigations be carried out on the basis of a clearly formulated problem using experimental procedures suited to the biological characteristics of the test substances and of the animals.