(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Annihilate
Definition:
(v. t.) To reduce to nothing or nonexistence; to destroy the existence of; to cause to cease to be.
(v. t.) To destroy the form or peculiar distinctive properties of, so that the specific thing no longer exists; as, to annihilate a forest by cutting down the trees.
(v. t.) To destroy or eradicate, as a property or attribute of a thing; to make of no effect; to destroy the force, etc., of; as, to annihilate an argument, law, rights, goodness.
(a.) Annihilated.
Example Sentences:
(1) At its centre was the Holocaust, the industrialised slaughter of 6 million Jews by the Nazis: an attempt at the annihilation of an entire people.
(2) Worst building Facebook Twitter Pinterest Where Merkel bosses other European leaders around ... a whole street was annihilated for the Justus Lipsius building, home of the Council of the European Union This is where Angela Merkel bosses other European leaders around: the Justus Lipsius building, home of the Council of the European Union.
(3) The event when one annihilation photon escapes from the detector without interaction while the other escapes after one Compton scattering interaction produces a characteristic component in the pulse-height spectrum.
(4) These correspond to the ordering processes by the migration and the annihilation of quenched-in excess vacancies, the annihilation of secondary defects and the diffusion of equilibrium vacancies, respectively.
(5) Other phenomena expected of an excitable medium, such as wave propagation of undiminished amplitude and annihilation of colliding wavefronts, were observed.
(6) The relationship between the fluorescence yield and the number of hits per domain depends on two parameters: the rate constant of bimolecular exciton annihilation and the dimension of the domain in which this annihilation occurs.
(7) Something has happened before J starts, and what that something is I can best describe as an annihilation of a people and an idea.
(8) In Game Four two home runs from Jhonny Peralta and a homer apiece from Triple Crown-winner Cabrera and Austin Jackson led the annihilation.
(9) Application of a depolarizing current pulse of brief duration during a critical region of the spontaneous cycle annihilated activity in some preparations exposed to [TTX] approximately 10(-7) M. These results were analyzed with the model of electrical activity described in the previous paper (Clay, J.R., R.M.
(10) Sulphate reduced adjuvanticity of the SLPs, and the number of sulphate groups required for complete annihilation increased with the chain length of the lipid.
(11) Smaller focal regions of hypoperfusion may be identified by computer emission tomography, either by the detection of single-photon emission or by paired detection of annihilation photons.
(12) In PET, organic molecules labeled with positron-emitting radionuclides are injected or inhaled, and the high-energy photons produced by annihilation events are detected by paired, integrated crystal detectors.
(13) Unhappy with just a share in the state, the Islamists wanted to own it entirely – and now, following three consecutive losses at the ballot box , they are the ones responsible for leading Libya towards annihilation.
(14) Positrons, emitted by 11C attract an electron, and the two masses are annihilated by emitting photons.
(15) Australia is still digesting the scale of Rudd's victory, which saw Howard and his Liberal party coalition annihilated at the polls.
(16) It is assumed that the triplet-triplet annihilation at 77 degrees K is related with the strong interaction between the chlorophyll molecules in the pigment complex of Photosystem I.
(17) He suggested the larger forum offered by the UN was instead important for countries such as Cuba or the small islands which risk annihilation by climate change to air their grievances.
(18) In fact were you to inhabit it, it might feel like you were disappearing, not unlike annihilation.
(19) Phase resetting and annihilation of repetitive firing in the ventricular myocardium were demonstrated by a brief current pulse of the proper magnitude applied at the proper phase.
(20) As Cohn himself pointed out, all his work was fundamentally concerned with the study of the same phenomenon: "the urge to purify the world through the annihilation of some category of human beings imagined as agents of corruption and incarnations of evil".