(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Annul
Definition:
(a.) To reduce to nothing; to obliterate.
(a.) To make void or of no effect; to nullify; to abolish; to do away with; -- used appropriately of laws, decrees, edicts, decisions of courts, or other established rules, permanent usages, and the like, which are made void by component authority.
Example Sentences:
(1) The unique structure we describe is a cytoplasmic organelle which, like annulate lamellae, is closely associated with the endoplasmic reticulum and is presumed to be related to the genesis of rough-surfaced endoplasmic reticulum in tumor cells.
(2) The description of the structure of epithelial cells includes: 1) the endoplasmic reticulum and ribosomes, 2) mitochondria, 3) the nucleus, 4) the golgi complex and secretory bodies, 5) lysosomes, 6) annulate lamellae, 7) luminal surface, 8) basal surface, 9) lateral surface, and 10) the nucleolar channel system.
(3) The following consequences can be drawn for the taxonomy and biochemistry of the tested organisms: e) The species status of M. gastri should be annuled.
(4) Both tumor cells frequently contained well-developed RER, zymogen-like granules, and annulate lamellae.
(5) A close association was observed annulate lamellae and granular endoplasmic reticulum.
(6) "It may be thought strange that I could abstain from a woman who to most people was so attractive," he told his lawyer during the annulment proceedings.
(7) The more the president rules by decree – and one faction in the Brotherhood argues that he should issue a constitutional decree of his own, annulling the content of the decree Scaf issued within hours of the closing of the presidential polls – the more he risks alienating his future political partners in the broad-tent political coalition he intends to set up both under him as president, and under the prime minister he intends to nominate.
(8) The sarcocysts of both species are trabeculated and their cyst walls have cytophaneres containing annulated fibrils and coarse, electron dense granules.
(9) Still, Rafsanjani – often accused of sitting on the fence – did not call outright for an annulment.
(10) Replacement of the common fresh weight or dry weight specific oxygen consumption by a more synthetic value calculated from ash-free dry weight specific oxygen consumption measurements, to annulate the body-size effect, is proposed for interspecific comparison over a wide range of body size, taking into account parameters such as temperature.
(11) The most unique ultrastructure feature was the presence of annulate lamellae in four of the six cases.
(12) If you are made bankrupt it is possible to get the bankruptcy order annulled if you can get your creditors to agree to what is called a fast track IVA.
(13) Among a "toolbox" of actions under consideration are: • full or partial annulment of the Oslo Accords, under which the Palestinian Authority (PA) was established • withholding tax revenues Israel collects on behalf of the PA • cancellation of permits for thousands of Palestinian labourers to work in Israel • withdrawal of travel privileges for senior PA officials • acceleration of building programmes in West Bank settlements • unilateral annexation of the main Jewish settlement blocks.
(14) This may suggest that annulate lamellae participate in protein synthesis.
(15) A specific organelle, the annulate lamellae or lamellar body, was seen in tight correlation with other structures near the nucleus.
(16) The methionine synergism for P. malhamensis growth is also negated when B12 activity is annulled by alkali treatment; MTA is not inactivated by such treatment.
(17) The similarities in structure to the nuclear envelope and the relation between annulate lamellae and other cellular organelles (especially endoplasmic reticulum and ribosomes) suggest that lamellae may be involved in the release, assembly or activation of stored development information.
(18) The annulated derivative N6-(1-naphthylmethyl)adenosine resulted in a very potent A2 agonist (A1 Ki = 24 nM, A2 Ki = 9.1 nM), whereas N6-(9-anthracenylmethyl)adenosine was virtually inactive (A1 Ki = 9,000 nM, A2 Ki = 29,000 nM).
(19) The omission of sodium or dextrose in the perfusion fluid annulled this effect.
(20) In March this year, an Indonesian court annulled a 17-year-old private contract with the water corporations Suez and Aetra on the basis of human rights violations resulting from a fourfold rise in tariffs since the utility was privatised, lower service coverage than promised, and water leakage levels of up to 44%.