(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Derogate
Definition:
(v. t.) To annul in part; to repeal partly; to restrict; to limit the action of; -- said of a law.
(v. t.) To lessen; to detract from; to disparage; to depreciate; -- said of a person or thing.
(v. i.) To take away; to detract; to withdraw; -- usually with from.
(v. i.) To act beneath one-s rank, place, birth, or character; to degenerate.
(n.) Diminished in value; dishonored; degraded.
Example Sentences:
(1) The observed increase in self-derogation over a 1-year period in persons with initially positive self-attitudes is discussed with regard to the literature on developmental disturbances in self-image; differential volunerability to self-devaluing experiences; and the relationship between change in, and level of, self-acceptance.
(2) Results indicate that health care presented within the context of not having a choice is derogated and that choice and patient mix combine to influence intentions to seek care.
(3) Results indicated an effect of sex identification; the male blunderer was derogated most by male subjects (n = 34) and the female most by female subjects (n = 34).
(4) However, whether or not suicidal behaviors are related to self-derogating feelings in the more remote past can be seen as a function of a sex-social-class-mode of suicidal response interaction.
(5) Inspectors found that senior staff at Durham Free School had allowed a culture to develop where it was acceptable for racist words and sexually derogative and homophobic terms to be used.
(6) Detaining non-suspects for up to seven days, virtually incommunicado and without effective review at the time, removing the right to silence on penalty of imprisonment, and criminalising any disclosure of detention, is excessive and disproportionate in view of existing powers, the level of terrorist threat, and the absence of any declared public emergency justifying derogation from protected human rights.
(7) Some derogations could attenuate the severity of these dispositions--as jurisprudence had taken progresses of Epileptology and therapeutics into consideration.
(8) The duty of care owed by the commonwealth to asylum seekers and refugees is non-derogable – it cannot be suspended or transferred.
(9) Self-derogators were judged to be submissive, elicited dominating reactions, and selected more topics with negative content.
(10) A particularly interesting interpretation of this phenomenon, consistent with a large body of clinical and experimental literature, ascribes it to self-derogation processes in low-PA persons and self-enhancement processes in high-PA persons.
(11) But Caoilfhionn Gallagher, representing the media with Mike Dodd, legal editor of the Press Association, said not knowing the names would be “a major derogation from the open justice principle” – and that the public had a right to know who, and what, was going on in public courts.
(12) We predicted that authoritarian actors would engage in defensive attribution, and authoritarian observers would derogate the other, to a greater extent than egalitarian perceivers.
(13) The commission should expand the EU-wide ban to cover all uses of neonicotinoids on all crops, and end the self-service approach to derogations.
(14) 10c derogation intent When the EU adopted the climate and energy package in December 2008, the 10c derogation was included as an exception to the rule that from 2013 onwards, all allowances for power companies should be auctioned rather than granted for free.
(15) Many Tories were demanding she went for a temporary derogation of human rights laws.
(16) Attitudes toward victims of AIDS were conceptualized as serving three possible functions: a value-expressive function (e.g., stigmatization), an ego-defensive function (e.g., homosexual prejudice), or a knowledge function (e.g., victim derogation).
(17) The report adds: "As they incorporate derogations from the principle of open justice, superinjunctions and anonymised injunctions can only be granted when they are strictly necessary.
(18) Experiments 1 and 2 showed that self-derogations connote submissiveness but are generally judged to be neutral in affiliation.
(19) The European parliament’s industry committee last month approved a rule change allowing Greece to join the scheme, the ‘10c derogation’ of the emissions trading system (ETS).
(20) Article 15 of the human rights convention allows a state to withdraw temporarily or derogate in legal terms from some of its rights in times of national emergency which threaten the life of the nation, to allow the use of measures that have to be "strictly required".