(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Dissolve
Definition:
(v. t.) To separate into competent parts; to disorganize; to break up; hence, to bring to an end by separating the parts, sundering a relation, etc.; to terminate; to destroy; to deprive of force; as, to dissolve a partnership; to dissolve Parliament.
(v. t.) To break the continuity of; to disconnect; to disunite; to sunder; to loosen; to undo; to separate.
(v. t.) To convert into a liquid by means of heat, moisture, etc.,; to melt; to liquefy; to soften.
(v. t.) To solve; to clear up; to resolve.
(v. t.) To relax by pleasure; to make powerless.
(v. t.) To annul; to rescind; to discharge or release; as, to dissolve an injunction.
(v. i.) To waste away; to be dissipated; to be decomposed or broken up.
(v. i.) To become fluid; to be melted; to be liquefied.
(v. i.) To fade away; to fall to nothing; to lose power.
Example Sentences:
(1) We investigated this suppression quantitatively, using a chemical assay for cell-bound and dissolved capsular polysaccharide.
(2) Thus Sephadex chromatography of the solution obtained by dissolving the antigen-antibody precipitate in these media repeatedly gave two peaks corresponding to anti-ovalbumin and ovalbumin.
(3) Although the brain AP50 is prominently phosphorylated by an endogenous protein kinase in isolated coated vesicle preparations, the neuronal AP50 was not detectably phosphorylated in intact cells as assessed by two-dimensional non-equilibrium pH gradient gel electrophoresis of labeled cells dissolved directly in SDS-containing buffers.
(4) After Listeria, a bacterium, is phagocytosed by a macrophage, it dissolves the phagosomal membrane and enters the cytoplasm.
(5) In muscle cells the mitochondria were in the process of dissolving and the sarcoplasmic reticulum formed elongate cisternae.
(6) Homogenates of these cells in chloroform-methanol solution showed an identical absorption spectrum with pure bilirubin dissolved in the same solution.
(7) However, in some patients absorption of the drug is markedly sensitive to changes in dissolution rate and new pharmacopoeal standards should not be defined until very rapidly-dissolving formulations have been studied.
(8) In the first few days of immersion high concentrations of dissolved metal ions were observed.
(9) It expresses the ratio between the partial pressure of the dissolved gas and the reduction of hydrostatic pressure during ascent (given as pressure gradient).
(10) Egypt has been without a sitting lower house of parliament since summer 2012, when it was dissolved by the country's supreme court .
(11) Each hand washing is filtered, and the residue collected on a membrane filter is dissolved in hydrochloric acid.
(12) An epidemic of abuse with "T's and blues" began in the late 1970's in which pentazocine-Talwin tablets ("T")--and the antihistamine tripelennamine (known as blues) were crushed, dissolved together, filtered, and injected intravenously.
(13) Osteoclasts dissolve bone mineral by the vectorial secretion of hydrogen ion at their osseous attachment site.
(14) This collagenolytic activity, which dissolved the collagen substrate, was derived from B. gingivalis and human GCF.
(15) Dexon's tensile strength is high initially and it retains its strength through the critical period of muscle-scleral wound healing, then dissolves in a rapid uniform manner.
(16) These results show that Mg-containing apatites dissolve to a greater extent than Mg-free apatites with the subsequent reprecipitation of Mg-poor apatites.
(17) In recent years, the clinical application of aerosol inhalation therapy has increased rapidly, however, many problems are not yet fully dissolved.
(18) In 1952, Clarence Agress performed an experiment on dogs to demonstrate his idea that a thrombus in a coronary artery could be dissolved without harm to the myocardium.
(19) The results show that when Cs is dissolved in aqueous buffer, the terminal atoms of residue 1 side chain are not available for binding to antibodies recognizing the face of the molecule defined by residues 1, 2, 3, 10, 11, suggesting that the chain is probably folded back under the molecule, as observed in the crystal structure.
(20) To further characterize the role of superoxide anion-radical in the vanadium redox cycling, the increase of optical density of vanadate(V) dissolved in Tris buffer was measured at 328 nm during the addition of KO2.