(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Overrule
Definition:
(v. t.) To rule over; to govern or determine by superior authority.
(v. t.) To rule or determine in a contrary way; to decide against; to abrogate or alter; as, God overrules the purposes of men; the chairman overruled the point of order.
(v. t.) To supersede, reject, annul, or rule against; as, the plea, or the decision, was overruled by the court.
(v. i.) To be superior or supreme in rulling or controlling; as, God rules and overrules.
Example Sentences:
(1) In one of Pruitt’s first official acts, for example, he overruled the recommendation of his own agency’s scientists, based on years of meticulous research, to ban a pesticide shown to cause nerve damage, one that poses a clear risk to children, farmworkers and rural drinking water supplies.
(2) Oscar Pistorius ‘to be released in August’ as appeal date is set for November Read more But the parole board at his prison overruled an emotional plea from the 29-year-old victim’s parents when it sat last week.
(3) "Gove's overruling by the prime minister is a victory for thousands of young people, teachers and athletes, and is a warning to this government that it cannot simply do what it likes.
(4) It’s the failure of an over-centralised prime ministerial office, too small to have real intellectual and research heft yet arrogant enough to overrule FCO advisers.
(5) Any attempts to overrule it undermine both the women's right to choose and doctor's right to practice.
(6) But, against his own wishes, he had to announce that the Saudi contract bid would go ahead because of the financial penalties involved, but when that reason was amended to Britain’s “best interests” it was widely assumed that Hammond had overruled him.
(7) It is not an option for the shadow cabinet to overrule him in favour of collectively supporting the proposal for military action because this would lead to them being sacked.
(8) We are amazed that a doctor's judgment is overruled in nine cases out of 10."
(9) A great portfolio might overrule this requirement but it is a great fall back.
(10) Asst Ch Con Roger Bannister said in a statement: “This man is not the only individual being investigated by Operation Enamel and our determination to bring others to justice is undaunted.” Saunders overruled the lead counsel, Eleanor Laws QC, who had recommended that Janner should be charged.
(11) He told the committee he would be willing to overrule Ofqual and press ahead if he believed the changes were right: "If they still had concerns and I still believe it is right to go ahead then I would do it, and on my head be it."
(12) The PI was seen as a supplementary source of information, instrumental to the physician-pharmacist-patient relationship, without the power to overrule the physician's or pharmacist's instructions.
(13) And now the European court of human rights keeps the judiciary honest, as it did in the Abu Qatada case itself last year when overruling our judges' effort to be relaxed about torture evidence as long as it was being allowed in Amman and not the Old Bailey.
(14) It argues that Webster does not overrule Roe v. Wade, but that it clarifies 3 points of law concerning abortion.
(15) NGO officials say Sudan's national security service has been overruling the state humanitarian affairs commission on issues of which aid groups are allowed to work, and where.
(16) And the Nauru files unveil how conditions in the camps are clinically euphemised for the outside world: critical incidents, in which refugees have attempted to kill themselves, or are raped or assaulted, are downgraded to the classifications “major” or “minor”, ensuring that Wilson – the security subcontractor on the island – won’t be fined for failing to report them in time; doctors’ orders that someone be moved for urgent medical treatment are overruled by a department slavishly determined to uphold a policy, regardless of medical consequence.
(17) Solomon led the London march early today with a megaphone but found her directions overruled when students, instructed via mobile phones, spontaneously sprinted toward parliament.
(18) Her mother the Duchess of Kent had wanted to call her Georgiana Charlotte Augusta Alexandrina Victoria, but was overruled by a cantankerous Prince Regent, the future George IV, who dictated during the ceremony that she be called Alexandrina Victoria instead in tribute to the Russian Tsar Alexander I.
(19) It’s hard for public servants to actually overrule somebody who might next week be sitting on the other side of the table at a Senate estimates hearing, grilling them,” he said.
(20) Ruling initially accepted by foreign secretary, Robin Cook, but a "feasibility study" ordered into the potential return June 2004 UK government tries to block return of islanders through two orders in council, royal decrees which declared no one had right of abode May 2006 The high court overruled the orders in council, describing their use to expel an entire population as repugnant 2007 Foreign office appeal rejected