(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Reverse
Definition:
(a.) Turned backward; having a contrary or opposite direction; hence; opposite or contrary in kind; as, the reverse order or method.
(a.) Turned upside down; greatly disturbed.
(a.) Reversed; as, a reverse shell.
(a.) That which appears or is presented when anything, as a lance, a line, a course of conduct, etc., is reverted or turned contrary to its natural direction.
(a.) That which is directly opposite or contrary to something else; a contrary; an opposite.
(a.) The act of reversing; complete change; reversal; hence, total change in circumstances or character; especially, a change from better to worse; misfortune; a check or defeat; as, the enemy met with a reverse.
(a.) The back side; as, the reverse of a drum or trench; the reverse of a medal or coin, that is, the side opposite to the obverse. See Obverse.
(a.) A thrust in fencing made with a backward turn of the hand; a backhanded stroke.
(a.) A turn or fold made in bandaging, by which the direction of the bandage is changed.
(a.) To turn back; to cause to face in a contrary direction; to cause to depart.
(a.) To cause to return; to recall.
(a.) To change totally; to alter to the opposite.
(a.) To turn upside down; to invert.
(a.) Hence, to overthrow; to subvert.
(a.) To overthrow by a contrary decision; to make void; to under or annual for error; as, to reverse a judgment, sentence, or decree.
(v. i.) To return; to revert.
(v. i.) To become or be reversed.
Example Sentences:
(1) This trend appeared to reverse itself in the low dose animals after 3 hr, whereas in the high dose group, cardiac output continued to decline.
(2) Application of 40 microM NiCl2 reversibly blocked It while leaving Is intact, whereas 20 microM CdCl2 reversibly blocked Is, but not It.
(3) The outward currents are sensitive to TEA and their reversal potentials differ.
(4) With NaCl as the major constituent of the bathing solution (potassium-free pipette and external solutions) the reversal potential (Er) of the noradrenaline-evoked current was about 0 mV.
(5) The HBV infection was tested by the reversed passive hemagglutination method for the HBsAg and by the passive hemagglutination method for the anti-HBs at the time of recruitment in 1984.
(6) If the method was taken into routine use in a diagnostic laboratory, the persistence of reverse passive haemagglutination reactions would enable grouping results to be checked for quality control purposes.
(7) Tests showed the cells survive and function normally in animals and reverse movement problems caused by Parkinson's in monkeys.
(8) In dorsoventral (DV) reversed wings at both shoulder or flank level, the motor axons do not alter their course as they enter the graft.
(9) Head-injured patients had a low thyroxine (T4), low triiodothyronine (T3), and high reverse T3.
(10) Dilutional studies comparing the mechanism of inhibition of monoamine oxidase produced by Gerovital H3 and by ipronizid demonstrated that Gerovital H3 was a reversible inhibitor of monoamine oxidase.
(11) Nucleotide, which is essential for catalysis, greatly enhances the binding of IpOHA by the reductoisomerase, with NADPH (normally present during the enzyme's rearrangement step, i.e., conversion of a beta-keto acid into an alpha-keto acid, in either the forward or reverse physiological reactions) being more effective than NADP.
(12) An axillo-axillary bypass procedure was performed in a high-risk patient with innominate arterial stenosis who had repeated episodes of transient cerebral ischemia due to decreased blood flow through the right carotid artery and reversal of blood flow through the right vertebral artery.
(13) What reforms there were could also be reversed, she warned.
(14) No reversions to wild-type levels were observed in 555 heterozygous offspring of crosses between homozygous Campines and normals.
(15) We have compared two new methods (a solvent extraction technique and a method involving a disposable, pre-packed reverse phase chromatography cartridge) with the standard method for determining the radiochemical purity of 99Tcm-HMPAO.
(16) Sickle and normal discocytes both showed membrane elasticity with reversion to original cell shape following release of the cell from its aspirated position at the pipette tip.
(17) These antagonists reverse NMDA-mediated long term influence in these brain areas.
(18) For dental procedures requiring tracheal intubation, one could perhaps use non-depolarizing muscle relaxants, like pancuronium, with reversal at the end of the procedure.
(19) We have recently described a nonnucleoside compound that specifically inhibits the reverse transcriptase of human immunodeficiency virus type 1 (HIV-1), the causative agent of AIDS.
(20) We have investigated some of the factors which affect the retention times of these substances in reversed-phase HPLC on columns of 5-micron octadecylsilyl silica.