(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Successor
Definition:
(n.) One who succeeds or follows; one who takes the place which another has left, and sustains the like part or character; -- correlative to predecessor; as, the successor of a deceased king.
Example Sentences:
(1) Environmental campaigners had been apprehensive about the chances of the Senate ratifying a new international treaty – a successor to the Kyoto protocol – to combat global warming unless a consensus had already been reached on Capitol Hill.
(2) As luck would have it, the outgoing Bartlet and his successor, Matt Santos, are currently dealing with a foreign crisis, too.
(3) With Everton heading for a sixth-placed finish in the Premier League, the additional television revenue and prospect of further funds from Fellaini, the club are confident of appointing an "equally significant" successor to Moyes, according to the chairman, Bill Kenwright.
(4) The chances of Sam Allardyce becoming the next England manager have been enhanced by his willingness to help the Football Association to mentor a young assistant who would be groomed as his successor.
(5) Academisation and a school system on the brink | Letters Read more Perry Beeches has been a favourite of Cameron, as well as former education secretary Michael Gove and his successor Nicky Morgan .
(6) The current president of the supreme court, Lord Phillips, who steps down at the end of September, welcomed his successor, praising his "wealth of judicial experience" and "ability to lead a collegiate court".
(7) Others believe that, despite the fact that some of his closest lieutenants are among those indicted by US authorities, he planned to use the time until the new election to ease a favoured successor into the post.
(8) With the White House backing away and fellow Republicans openly considering successors, Mr Lott's hard-fought campaign to sit out the controversy appeared doomed.
(9) Arapahovius seems to have had no phylogenetic successors.
(10) He considers himself more of a tracksuit coach, despite seeing his influence with the younger age groups at St George’s Park diminished since Matt Crocker swapped Southampton for the FA to become head of player and coach development, but would be more than happy to be part of the body’s consultation process as they seek to identify Hodgson’s successor.
(11) 'Have a thick skin' – sex discrimination commissioner's advice to her successor Read more Labor said it was “a disgrace for women everywhere” that the government was delaying appointing a replacement for Elizabeth Broderick, the long-serving commissioner whose term expired four months ago.
(12) But the damage from the whole affair and inevitable scrutiny of her successor might just mean they take a more even-handed approach to the job.
(13) The constitution states that he will remain president until his successor is elected,” Kikaya said.
(14) The two reformists Mr Mousavi and Mehdi Karroubi have sought to portray themselves as the true heirs of the Islamic revolution's spiritual leader, the late Ayatollah Khomeini, but this tactic has since worn thin and Khomeini's successor Ayatollah Ali Khamenei has stepped up his drive to paint Mousavi and Karroubi as western-run heretics.
(15) Spain goes to the polls at the weekend to find a successor to the administration of José Luis Rodríguez Zapatero.
(16) Also note chatter of Bernanke stepping down next week (6-weeks early), if successor Yellen gained full Senate approval, allowing her to chair the December FOMC meeting.
(17) The process to select his successor will be independent of government, but we will be keeping a close eye on the situation.
(18) It was in that period that Ronald Reagan lent official US recognition to the Palestine Liberation Organisation, making a move that would have been too costly for his successor, Bush the elder.
(19) Political conflict stemming from parliamentary disputes should be resolved within the legislative council.” Earlier this month, and just one day after Leung’s successor was elected in a controversial election, police announced they would charge nine people involved in the 2014 democracy protests.
(20) De Boer's successor's first tasks will be to keep the US aboard the negotiations and to clear up the vexed question of the legal status of the Copenhagen accord , the deal struck at Copenhagen by a small group but not endorsed by a majority of countries.