(v. t.) To annul by an authoritative act; to abolish by the authority of the maker or his successor; to repeal; -- applied to the repeal of laws, decrees, ordinances, the abolition of customs, etc.
(v. t.) To put an end to; to do away with.
Example Sentences:
(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Undo
Definition:
(v. t.) To reverse, as what has been done; to annul; to bring to naught.
(v. t.) To loose; to open; to take to piece; to unfasten; to untie; hence, to unravel; to solve; as, to undo a knot; to undo a puzzling question; to undo a riddle.
(v. t.) To bring to poverty; to impoverish; to ruin, as in reputation, morals, hopes, or the like; as, many are undone by unavoidable losses, but more undo themselves by vices and dissipation, or by indolence.
Example Sentences:
(1) We cannot undo the damage it has done to our air quality,” she said.
(2) I am not a Muslim but I see that the cover has been read as yet more provocation, even an undoing of the unity of the marches in Paris and other cities.
(3) Amid public outcry over the Bettencourt case, Sarkozy is now likely to be forced into a U-turn before the next election, undoing his tax reforms.
(4) His interventions over the next week - first with the miners then with his former army colleagues as hundreds of thousands took to the streets of Belgrade - would prove his ex-master's undoing.
(5) He told the chair, Alexis Jay: “We will never be able to undo the wrongdoing to these children.
(6) But the role opened my eyes to certain aspects of online gaming, such as harassment, abuse, threats and even stalking, and in many ways, it is an unhappy experience that I wish I could undo.
(7) With three weeks left to election day, the onus is on Obama to mount a strong comeback in Tuesday's Long Island debate to undo some of the damage caused by his dismal showing in the first of the presidential debates in Denver a fortnight ago.
(8) Obama won praise from world leaders for his promises to undo George Bush's environmental record, but there is growing scepticism abroad that Democrats will be able to overcome opposition in Congress and pass legislation that would put America on a path to cutting its carbon emissions.
(9) Arab regional governments – and even Iran – have belatedly seen their own storm clouds of extremism, but there is tremendous work required to undo what has been done.
(10) All efforts to undo environmental protections put in place by Obama, he said, would face lengthy and compulsory processes of consultation and review, as well as the strongest possible legal challenges at every turn.
(11) President-elect Trump will be able to undo the programs and cast them into the dustbin of history with equal speed and ease.
(12) Against the top sides England will leak goals, and that will ultimately be our undoing.
(13) He is praised for responding to a chemical attack in Syria with airstrikes, for generally projecting strength in foreign policy, for undoing Obama-era regulations on the environment and business, for installing a conservative supreme court justice, for protecting American jobs, and for not letting people tell him what he can’t do.
(14) Now Google might be required to undo the changes – although Auke Haagsma, a lawyer advising the lobby group Icomp , which is critical of Google's policies, said that would be like trying to "unscramble the egg".
(15) The projected increase in 2016 would return poverty rates to their 2007 levels, undoing nearly a decade’s worth of gains,” the report stated.
(16) Labour cannot afford to undo the coalition's cuts in the next government and must expect to be unpopular, one of the party's most senior finance spokesmen will say on Friday.
(17) Jeremy’s main fault was his unfortunate choice of friends – notably Peter Bessell MP, who jointly and foolishly entered into the long-running payoff drama with Scott which was his undoing.
(18) It has helped cement Qatar’s international reach and legitimacy, yet ironically has now played a part in its undoing.
(19) The former Irish prime minister John Bruton says it would “undo much of the work of the peace process and create huge questions over borders and labour market access”.
(20) The author examines how these negative affects, the accompanying victim role, and oppositional defiance enable angry adolescents to defend against depression and loss, to demand nurturance from others, to protect their precarious inner autonomy, and to undo their humiliation and shame by vengeance and reversal.