(1) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(2) LPS also abrogated the ability of recombinant interferon-gamma (r.IFN-gamma) to enhance macrophage larvicidal activity.
(3) Release of 51Cr was apparently a function of immune thymus-derived lymphocytes (T cells) because it was abrogated by prior incubation of spleen cells with anti-thymus antiserum and complement but was undiminished by passage of spleen cells through nylon-wool columns.
(4) In contrast, insertion of a pre-S(1) sequence between HBcAg residues 75 and 83 abrogated recognition of HBcAg by 5 of 6 anti-HBc monoclonal antibodies and diminished recognition by human polyclonal anti-HBc.
(5) Furthermore, exogenous IL-1, IL-2, IL-4, interferon-gamma, or a rat Con A supernatant failed to abrogate DFMO inhibition.
(6) A T cell was responsible for the suppressive effects on LAK generation because suppression was abrogated by treatment of alloimmune cells with anti-T serum plus complement.
(7) Inhibitors of DC clustering, including trypsin, paraformaldehyde, and tunicamycin, abrogated the ability of DC to support antigen presentation and lectin-mediated proliferation.
(8) Bound fluorescyl ligand, increased ionic strength (0.5 M NaCl) or basic pH (greater than 8.0) abrogated cryoprecipitation.
(9) One of the renal antigens recognized by 2B4.14.1 was identified as Tamm-Horsfall glycoprotein (THGP), based on the ability of the antibody to recognize THGP in western immunoblots and the abrogation of immunohistologic reactivity of the antibody by preincubation with purified THGP.
(10) Furthermore, treatment of AC with lysosomotropic agents abrogated thymocyte proliferation induced by PE but not SEB.
(11) Pretreatment with OKT3, together with a monoclonal anti-DR antibody and complement, did not abrogate the T-colony forming capacity.
(12) Resistance of the rat induced by C. liquefaciens to tumor cells was also abrogated by Trypan Blue treatment just 1 day before tumor cell inoculation.
(13) Serum SIRS-inducing activity was abrogated by treatment with proteinase K or boiling, but was not affected by dialysis, acidification to pH 2, or heating to 56 degrees C. This serum factor could be distinguished functionally and antigenically from SIRS and from interferon (IFN) alpha or IFN gamma.
(14) It is shown that while not affecting other mononuclear cells viability, this IT is capable of selectively destroying human monocytes after 24 h exposure thus resulting in the abrogation of monocyte support for PHA reactivity in mononuclear cell preparations.
(15) Tetrodotoxin or nifedipine abrogated the effects of IC, C-Ch and PE but did not influence the effect of gamma-interferon on C2 synthesis.
(16) Preincubation of rIL-1 with a specific antibody abrogated and heat-inactivation destroyed this activity.
(17) This IFN-gamma-mediated suppression was monocyte dependent because it was completely abrogated by monocyte, but not T cell depletion.
(18) In contrast, these responses were both abrogated by hyperpolarization with the K+ ionophore valinomycin.
(19) Dilution of the latter detergent lysate with phosphate buffered saline exhibited no effect on the detection of the two additional components, while further treatment of the lysate with NP-40 buffer abrogated them to be detected.
(20) Release was abrogated by omission of myeloperoxidase or H2O2, heating of MPO, or addition of azide, cyanide, or catalase.
Approbation
Definition:
(n.) Proof; attestation.
(n.) The act of approving; an assenting to the propriety of a thing with some degree of pleasure or satisfaction; approval; sanction; commendation.
(n.) Probation or novitiate.
Example Sentences:
(1) Experiments on animals have found the stabilization of the structure of approbated canned goods modified with phosphate starches, such as maze, amylopectin and potato (TY 18 RSFSR 279-73) ones, causes lowering of the biological value of the product by comparison with analogous native starches.
(2) New spin-labels based on iodine and hydrargirum containing imidazolids were approbated on the bovine serum albumin (BSA) molecule.
(3) The clinical approbation of the method gave similar results of the capacitance blood flow with the literature data and with the rheographic method of determination of the cerebral blood flow.
(4) Garthoff observes that "in the United States, there was almost universal approbation for President Kennedy's handling of the crisis."
(5) In the light of the mentioned data, the author considers it expedient to work out a programme of special researches for development of a method of prognosticating initial myopia and a correction of several ways for approbation of existing methods of prevention of progressive myopia.
(6) Clearly moved by the support his family and daughter have received, he said the attack, in which Malala was shot by a Pakistan Taliban gunman while making her way home on a school bus, had united his nation in approbation.
(7) It is established that urine from healthy control cigarette smokers and from non-smoking greenhouse workers contacting with a complex of different pesticides significantly increased frequency of chromosome aberrations in the approbated test-system.
(8) They made such strides against ignorance and the unknown, firm in their sense of divine approbation, it seems a belief in progress came naturally to them.
(9) In the process of approbation on clinical material the method revealed an elevated level of CIC in the sera of patients in comparison with their level in the sera of healthy donors.
(10) The approbation of her fellow peers means a lot to Trumpers, for she believes that it's the House of Lords, which she still attends every day when it's sitting, that has kept her going all these years.
(11) To receive Beijing's approbation is something of a novelty for Taiwan.
(12) The main results of the ALDA approbation are given account of, which demonstrated a high level sensitivity and specificity of the algorithm and its applicability to most USSR-produced computers.
(13) It was approbated in 23 patients with duodenal ulcers, postvagotomy syndromes, and gastroduodenitis.
(14) The method was approbated in experiment with 10 adult dogs and used in 3 patients with long-standing marginal fractures of the acetabulum.
(15) Comparison with an earlier study revealed that although the rate of approbation for mental and psychosomatic work-related illnesses (about 30%) is much lower than for all work-related illnesses (about 90%), there has been a considerable increase over the years.
(16) The data on the approbation of the diagnostic value of the enzyme immunoassay (EIA) system for the determination of diphtheria toxin in the blood sera of diphtheria patients and persons suspected for diphtheria are presented.
(17) Approbation of the system at industrial enterprises contributed to the improvement of the social-medical and social-economic effectiveness of the diet therapy under industrial conditions.
(18) The morphometrical index of viability of the conserved kidneys can be used in experimental transplantology for approbation of new solutions before their application in clinical practice.
(19) But while some medical interventions such as organ transplants to replace malfunctioning livers and kidneys, or vaccines to boost the immune system, command wide social acceptance, others invite moral approbation.
(20) The final approbation or disapproval of a drug after NDA approval (phase 4) will continue to be in the hands of the participating physician as long as he can establish scientifically that the drug is the best possible agent for him to use in healing the sick and comforting the dying.