What's the difference between abstringe and unbind?

Abstringe


Definition:

  • (v. t.) To unbind.

Example Sentences:

Unbind


Definition:

  • (v. t.) To remove a band from; to set free from shackles or fastenings; to unite; to unfasten; to loose; as, unbind your fillets; to unbind a prisoner's arms; to unbind a load.

Example Sentences:

  • (1) Thus, although the fast sodium inactivation process is not required for tonic and use-dependent block of INa by disopyramide, it contributes to the fast phase of block development and unbinding from use-dependent block.
  • (2) Two calcium antagonistic drugs, nifedipine and mesudipine, were investigated and as a result averaged rate constants of binding and unbinding were evaluated.
  • (3) Physical theories have been developed to describe many aspects of their conformational behaviour, such as the preferred shapes and shape transformations of closed vesicles, and the shape fluctuations, random-surface configurations, and adhesion and unbinding of interacting membranes.
  • (4) Assuming a reversible one-to-one binding reaction, the time course of DHO binding and unbinding was analysed under a variety of conditions.
  • (5) Sanguinarine may produce a K+-like effect upon the Na pump with consequent unbinding of ouabain.
  • (6) The rate constants for binding and unbinding of ATP were estimated from the dependence of the mean open time on [ATP] and from the Ki.
  • (7) The rate for unbinding during depolarization was independent of pHo.
  • (8) We suggest that these conformational changes arise from the unbinding to DNA of certain basic tails of histone(s), and that a competition for DNA binding locations exists upon the reassociation.
  • (9) These findings suggest than AN-132 has use dependent inhibitory action on the fast sodium channel by binding to the channel mainly during its activated state and that the unbinding rate of the drug during diastole is very slow.
  • (10) Because in most cases these fit a single exponential with a mean open duration like that of modified channels, we conclude that voltage-dependent toxin unbinding produced a mixed population of unmodified and modified openings.
  • (11) The extent of the contribution of the process of agonist binding and unbinding to adenylate cyclase activation has not been demonstrated or quantified.
  • (12) It is interesting that encainide and flecainide unbind slowly (15-20 seconds), whereas lidocaine and moricizine unbind rapidly (0.2-1.3 seconds).
  • (13) Therefore, sodium channel states regulate the binding and unbinding behaviour of antiarrhythmic drugs.
  • (14) Such [Ca2+]i-transients in muscle are actually subcellular spatio-temporal events that are determined dynamically by i) diffusional fluxes of Ca2+, ii) by the binding or unbinding of Ca2+ to ligands such as troponin c and calmodulin, and iii) by the various cellular processes, such as release of Ca2+ from sarcoplasmic reticulum, that produce fluxes of Ca2+ across the membranes bounding organelles or the cell.
  • (15) According to the model, RAC109-I and RAC109-II have significantly different unbinding rate constants for channels when they exist predominantly in rested, activated, or inactivated states, as well as significantly different binding rate constants when channels are activated.
  • (16) We conclude that binding and unbinding of one molecule of ATP determine the gating of ATP-sensitive K+ channel.
  • (17) The dissociation rate constant of DHO unbinding remained unchanged (approximately 0.06 s-1).
  • (18) Estimates of binding and unbinding rate constants for the sodium channel during the action potential plateau and after repolarization were of the same order as previous results obtained using microelectrode methods in vitro.
  • (19) Increasing the concentration of drug increased the rate of binding but had little or no effect on unbinding, as expected for a simple bimolecular reaction.
  • (20) Binding and unbinding of MK-801 seems to be possible only if the N-Me-D-Asp-operated channel is in the transmitter-activated state: MK-801 was effective only when applied simultaneously with N-Me-D-Asp, and recovery from MK-801 blockade was speeded by continuous exposure to N-Me-D-Asp [time constant (tau) approximately equal to 90 min at -70 to -80 mV].

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