(n.) Incomprehensibility of things; the doctrine held by the ancient Skeptic philosophers, that human knowledge never amounts to certainty, but only to probability.
Example Sentences:
Catalepsy
Definition:
(n.) Alt. of Catalepsis
Example Sentences:
(1) Injection of a low dose of haloperidol, that has no obvious behavioral effects in normal mice, produces akinesia, catalepsy, and somatosensory neglect in MPTP-treated mice.
(2) The novel anxiolytic drug, buspirone, reverses catalepsy induced by haloperidol.
(3) Indomethacin and studied prostaglandins did not influence inhibitory action of FDP on haloperidol-induced catalepsy.
(4) Both antagonists produced catalepsy as evidenced by dose-dependent increases in step- down latency.
(5) Joint administration of WA-335 and L-DOPA with an inhibitor of peripheral decarboxylase, or WA-335 and amantadine produced a stronger antagonistic effect (spiroperidol catalepsy) than either of these substances separately.
(6) Finally 6 patients undergoing DDP with Timiperone in combination with trihexyphenidyl suffered no symptoms of catalepsy but sometimes had mild vomiting episodes (1-4 times a day).
(7) Finally, Lu 19-005 antagonized the catalepsy induced by perphenazine.
(8) All rats were tested for catalepsy and at the end of the last catalepsy test, striatal DOPAC, HVA and ACh were determined.
(9) Bilateral intrastriatal injections of quinolinic acid (QA) (180 nmoles) induced weight loss and neurologic and behavioral deficits including convulsions, decreased catalepsy response to haloperidol, increased nocturnal locomotor activity, and abnormal feeding behavior in adult male Sprague-Dawley rats.
(10) Studies on the mechanism of post-etorphine catalepsy.
(11) This dose of haloperidol alone caused only a slight, gradually developing catalepsy, while alphaMT alone caused none.
(12) Administration of oxotremorine to mice produced centrally-mediated effects, such as catalepsy and tremor, and peripheral muscarinic actions, such as diarrhoea and lachrymation.
(13) The results, together with a literature survey on the anticholinergic effects on neuroleptic-induced catalepsy and inhibition of avoidance behavior, are related to biochemical findings and clinical effects.
(14) The action of opiates leading to an inhibition of flexor alpha-motoneurones may contribute to akinesia and catalepsy, and opioid-induced muscular rigidity.
(15) In a second experiment, thioridazine, dopamine, norepinephrine, serotonin and their metabolites were assayed in the brain of the rat after acute administration of the enantiomers of thioridazine and the assessment of catalepsy.
(16) When the catalepsy score was almost maximal (60 s, measured by the bar-test), the rats were handled, exposed to cold (3 degrees C) or immobilized.
(17) A series of aryl-piperazine analogues of buspirone and other 5-hydroxytryptaminergic agonists were tested for their ability to reverse haloperidol induced catalepsy.
(18) MK-801 also potentiated the anticataleptic effect of scopolamine and bromocriptine against haloperidol-induced catalepsy.
(19) Striatal dopamine (DA) stores were only minimally depleted at the time of catalepsy potentiation.
(20) Catalepsy, measured by the duration of loss of righting reflex (DLRR) in catatonic animals, was induced by larger doses of both ketamine and morphine and in each case was reduced by a larger dose of naloxone.