What's the difference between accrual and increase?
Accrual
Definition:
(n.) Accrument.
Example Sentences:
(1) The study was terminated prior to accrual of the planned number of patients because of the statistically significant difference in efficacy between treatments found at interim analysis.
(2) Nonparametric estimates for all possible values of accrual duration and total study length required to achieve a specified power and level of significance are given assuming a proportional hazards model comparing two treatment groups.
(3) The tamoxifen or placebo treatment continued to death or to 10 months after accrual into the trial was stopped.
(4) This argues against a strategy of optional stopping of information accrual during the fixation of SL and is in line with a strategy of either fully neglecting or fully encoding SL.
(5) Side effects occurred despite dose reduction; therefore, protocol accrual was prematurely closed.
(6) Phylogenetically, a succession of structural innovations steadily enhanced the flow capacity of the larynx and rendered the mechanism more versatile, most recently with the accrual of phonation (in mammals), pressurized closure (in primates and odontocetes), and vocal formants and efficiency (in man).
(7) It is critical that interim statistical reports be interpreted correctly so as not to affect accrual adversely.
(8) This paper discusses practical aspects of patient accrual and interim analysis in this study.
(9) Postoperative memory, measured with delayed free recall, and postoperative mental performance, measured with the frequency accrual speed test index, were both significantly less impaired in the propofol group.
(10) Methods of determining appropriate combinations for the accrual and follow-up periods are given and the unique cost effective choice of accrual and follow-up periods is presented.
(11) On the other hand, the efficiency of the proportions test can drop to 72% or less for trials in which the accrual period exceeds the mean survival, as is often the case in trials to treat cancer.
(12) Rees – who turns 60 next month when his pension accruals will come to an end – will step down as deputy chief executive at the end of April.
(13) Rigid protocol design was the primary deterrent to accrual, especially for medical oncologists.
(14) The analysis was motivated by concerns over low accrual rates and a lower than expected response rate.
(15) The model has the advantages of predicting the time course of costs, allowing for different accrual and follow-up costs, and being amenable to revision during the conduct of a trial.
(16) Congruity effects arise because the duration of each evidence accrual is increased and the quality of the information is reduced as the distance of the stimulus representations from the instruction-activated reference point increases.
(17) Present annual accrual is approximately 2000 patients per year; 38 protocols are actively accruing patients while follow-up continues on 14 studies that are closed to patient entry.
(18) The $465 fee is an application fee, but a lot of the documents required in the application also lead to an accrual of additional fees – such as school transcripts, records from officials, photos, mailing.
(19) Current cancer care programmes in Sweden are listed, together with some examples of patient accrual in trials within regional and national programmes.
(20) In contrast, the development of the basolateral surface, which requires much less membrane accrual, was unaffected by PEM.
Increase
Definition:
(v. i.) To become greater or more in size, quantity, number, degree, value, intensity, power, authority, reputation, wealth; to grow; to augment; to advance; -- opposed to decrease.
(v. i.) To multiply by the production of young; to be fertile, fruitful, or prolific.
(v. i.) To become more nearly full; to show more of the surface; to wax; as, the moon increases.
(v. t.) To augment or make greater in bulk, quantity, extent, value, or amount, etc.; to add to; to extend; to lengthen; to enhance; to aggravate; as, to increase one's possessions, influence.
(v. i.) Addition or enlargement in size, extent, quantity, number, intensity, value, substance, etc.; augmentation; growth.
(v. i.) That which is added to the original stock by augmentation or growth; produce; profit; interest.
(v. i.) Progeny; issue; offspring.
(v. i.) Generation.
(v. i.) The period of increasing light, or luminous phase; the waxing; -- said of the moon.
Example Sentences:
(1) Intrathecal injection of zopiclone potentiated morphine antinociception, while the intracerebroventricular injection of zopiclone failed to enhance morphine antinociception and the intracerebroventricular injection of flumazepil to antagonize the intraperitoneal-zopiclone-induced increase in morphine antinociception.
(2) Synthesis of choline esterase on the medium with acetylcholine at a concentration of 1% was increased more than twofold upon addition of glucose at a concentration of 0.1%.
(3) It is supposed that delta-sleep peptide along with other oligopeptides is one of the factors determining individual animal resistance to emotional stress, which is supported by significant delta-sleep peptide increase in hypothalamus in stable rats.
(4) Correction for within-person variation in urinary excretion increased this partial correlation coefficient between intake and excretion to 0.59 (95% CI = 0.03 to 0.87).
(5) The significance of minor increases in the serum creatinine level must be recognized, so that modifications of drug therapy can be made and correction of possibly life-threatening electrolyte imbalances can be undertaken.
(6) Increased plasmin activity was associated with advancing stage of lactation and older cows after appropriate adjustments were made for the effects of milk yield and SCC.
(7) Technical factors that account for increased difficulty in these patients include: problems with guide catheter impaction and ostial trauma; inability to inflate the balloon with adequate guide catheter support; and need for increased intracoronary manipulation.
(8) In conclusion, in S-rats a glucose-stimulated insulin release is accompanied by an increase in IBF, but this is not observed in P-rats.
(9) Following in vitro C activation in NHS by delta IgG, the 40 KD C4d component increased markedly.
(10) The fraction of the viral dose which became cell associated was independent of the incubation temperature and increased with increasing target membrane concentration.
(11) At the early phase of the sensitization a T-cell response was seen in vitro, characterized by an increased spleen but no peripheral blood lymphocyte reactivity to T-cell mitogens at the same time as increased reactivity to the sensitizing antigen was detected.
(12) Maximum increases in portal plasma secretin concentrations of 143, 146 and 190% and maximum increases in VIP of 116, 155 and 147% after, respectively, intraduodenal 0.1 M NaHCO3, 0.1 M Na2CO3, and 0.025 M NaOH were found.
(13) These results demonstrate that increased availability of galactose, a high-affinity substrate for the enzyme, leads to increased aldose reductase messenger RNA, which suggests a role for aldose reductase in sugar metabolism in the lens.
(14) The cross sectional area of the aortic lumen was gradually decreased while the length of the stenotic lesion gradually increased by using strips with different width.
(15) Such an increase in antibody binding occurred simultaneously with an increase in the fluidity of surface lipid regions, as monitored by fluorescence depolarization of 1-(trimethylammoniophenyl)-6-phenyl-1,3,5-hexatriene.
(16) Both lymph flow from cannulated pancreatico-duodenal lymphatics and intralymphatic pressure in the non-transected ones increased significantly.
(17) Increased dietary protein intake led to increased MDA per nephron, increased urinary excretion of MDA, and increased MDA per milligram protein in subtotally nephrectomized animals, and markedly increased the glutathione redox ratio.
(18) It has been generally believed that the ligand-binding of steroid hormone receptors triggers an allosteric change in receptor structure, manifested by an increased affinity of the receptor for DNA in vitro and nuclear target elements in vivo, as monitored by nuclear translocation.
(19) However, four of ten young adult outer arm (relatively sun-exposed) and one of ten young adult inner arm (relatively sun-protected) fibroblasts lines increased their saturation density in response to retinoic acid.
(20) Addition of phospholipase A2 from Vipera russelli venom led to a significant increase in the activity of guanylate cyclase in various rat organs.