(v. t.) To heap up in a mass; to pile up; to collect or bring together; to amass; as, to accumulate a sum of money.
(v. i.) To grow or increase in quantity or number; to increase greatly.
(a.) Collected; accumulated.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(5) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(6) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(7) In addition, the guanosine 3',5'-cyclic monophosphate accumulation response was less impressive in glomeruli than the guanylate cyclase response in IMCD tissue.
(8) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(9) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(10) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(11) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(12) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(13) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
(14) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(15) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(16) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(17) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(18) Accumulating evidence indicates that for most tumors, the switch to the angiogenic phenotype depends upon the outcome of a balance between angiogenic stimulators and angiogenic inhibitors, both of which may be produced by tumor cells and perhaps by certain host cells.
(19) The aim of our experiments was to investigate firstly whether during an acute inflammatory process platelets accumulate in the inflamed area and secondly whether the inflammation has an effect on the properties of the platelets.
(20) The accumulated evidence would strongly favor an affirmative answer.
Grow
Definition:
(v. i.) To increase in size by a natural and organic process; to increase in bulk by the gradual assimilation of new matter into the living organism; -- said of animals and vegetables and their organs.
(v. i.) To increase in any way; to become larger and stronger; to be augmented; to advance; to extend; to wax; to accrue.
(v. i.) To spring up and come to matturity in a natural way; to be produced by vegetation; to thrive; to flourish; as, rice grows in warm countries.
(v. i.) To pass from one state to another; to result as an effect from a cause; to become; as, to grow pale.
(v. i.) To become attached of fixed; to adhere.
(v. t.) To cause to grow; to cultivate; to produce; as, to grow a crop; to grow wheat, hops, or tobacco.
Example Sentences:
(1) The cotransfected cells do not grow in soft agar, but show enhanced soft agar growth relative to controls in the presence of added aFGF and heparin.
(2) Given Australia’s number one position as the worst carbon emitter per capita among major western nations it seems hardly surprising that islanders from Fiji, Samoa, Vanuatu and other small island developing states have been turning to Australia with growing exasperation demanding the country demonstrate an appropriate response and responsibility.
(3) Thus, B cells that grow spontaneously from the peripheral blood of SS patients spontaneously produce a B-cell growth factor.
(4) Madrid now hopes that a growing clamour for future rescues of Europe's banks to be done directly, without money going via governments, may still allow it to avoid accepting loans that would add to an already fast-growing national debt.
(5) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(6) By growing purified human cytotrophoblasts under serum-free conditions and manipulating the culture surface, we were able to disassociate morphologic from biochemical differentiation.
(7) The form of the harvested crop, varietal characteristics and annual growing conditions have less bearing.
(8) In order for the club to grow and sustain its ability to be a competitive force in the Premier League, the board has made a number of decisions which will strengthen the club, support the executive team, manager and his staff and enhance shareholder return.
(9) The move to an alliance model is not only to achieve greater scale and reach, although growing from 15 partner organisations to 50 members is not to be sniffed at.
(10) The rate of nuclei stained by Pr-122 is different from that of Pr-192 in both growing and quiescent cultures.
(11) "We presently are involved in a number of intellectual property lawsuits, and as we face increasing competition and gain an increasingly high profile, we expect the number of patent and other intellectual property claims against us to grow," the company said.
(12) Brewdog backs down over Lone Wolf pub trademark dispute Read more The fast-growing Scottish brewer, which has burnished its underdog credentials with vocal criticism of how major brewers operate , recently launched a vodka brand called Lone Wolf.
(13) Their adaptive problems became worse while growing older until the age of 20.
(14) This receptor and a growing family of related cytokine receptors share homologous extracellular features, including a well-conserved WSXWS motif.
(15) In the DAUDI cell system, the acquired capability of tumor cell variants to grow in the presence of a relatively high concentration of vinblastine (VBL) is associated with a marked increase to NK and LAK susceptibility.
(16) In our work with bacteriophage T4, we observed that several T4 am mutants could grow on JM105.
(17) This will help nursing grow as a profession, particularly through entrepreneurial and intrapreneurial efforts.
(18) In WI-38, a normal human fibroblast, the rates of degradation of short lived and long lived proteins are identical whether the cultures are growing exponentially or are density-inhibited.
(19) Mu does not grow lytically in or kill him bacteria but can lysogenize such hosts.
(20) However, growing accustomed to “this strange atmosphere”, the Observer man became dazzled by Burgess’s “brilliance and charm”.