(v. t.) To heap up in a mass; to pile up; to collect or bring together; to amass; as, to accumulate a sum of money.
(v. i.) To grow or increase in quantity or number; to increase greatly.
(a.) Collected; accumulated.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(5) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(6) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(7) In addition, the guanosine 3',5'-cyclic monophosphate accumulation response was less impressive in glomeruli than the guanylate cyclase response in IMCD tissue.
(8) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(9) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(10) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(11) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(12) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(13) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
(14) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(15) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(16) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(17) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(18) Accumulating evidence indicates that for most tumors, the switch to the angiogenic phenotype depends upon the outcome of a balance between angiogenic stimulators and angiogenic inhibitors, both of which may be produced by tumor cells and perhaps by certain host cells.
(19) The aim of our experiments was to investigate firstly whether during an acute inflammatory process platelets accumulate in the inflamed area and secondly whether the inflammation has an effect on the properties of the platelets.
(20) The accumulated evidence would strongly favor an affirmative answer.
Save
Definition:
(n.) The herb sage, or salvia.
(a.) To make safe; to procure the safety of; to preserve from injury, destruction, or evil of any kind; to rescue from impending danger; as, to save a house from the flames.
(a.) Specifically, to deliver from sin and its penalty; to rescue from a state of condemnation and spiritual death, and bring into a state of spiritual life.
(a.) To keep from being spent or lost; to secure from waste or expenditure; to lay up; to reserve.
(a.) To rescue from something undesirable or hurtful; to prevent from doing something; to spare.
(a.) To hinder from doing, suffering, or happening; to obviate the necessity of; to prevent; to spare.
(a.) To hold possession or use of; to escape loss of.
(v. i.) To avoid unnecessary expense or expenditure; to prevent waste; to be economical.
(a.) Except; excepting; not including; leaving out; deducting; reserving; saving.
(conj.) Except; unless.
Example Sentences:
(1) Former Regional director for Latin American Caribbean and Middle East, Save the Children.
(2) There is precedent in Islamic law for saving the life of the mother where there is a clear choice of allowing either the fetus or the mother to survive.
(3) There was a 35% decrease in the number of patients seeking emergency treatment and one study put the savings in economic and social costs at just under £7m a year .
(4) But the Franco-British spat sparked by Dave's rejection of Angela and Nicolas's cunning plan to save the euro has been given wings by news the US credit agencies may soon strip France of its triple-A rating and is coming along very nicely, thank you. "
(5) As calls grew to establish why nobody stepped in to save Daniel, it was also revealed that the boy's headteacher – who saw him scavenging for scraps – has not been disciplined and has been put in charge of a bigger school.
(6) It’s not to punish the public, it’s to save the NHS and its people.” Another commenter added: “Of course they should strike.
(7) The Italian coastguard ship Bruno Gregoracci docked in Malta at about 8am and dropped off two dozen bodies recovered from this weekend’s wreck, including children, according to Save the Children.
(8) Leaders of Tory local government are preparing radical proposals for minimum 10% cuts in public spending in the search for savings.
(9) Johnson said the move would save businesses £350m from not having to meet the more exacting standards, which will now only have to be met by buses.
(10) We believe our proposal will save taxpayers about £4m and reduce by about 11,000 the number of legally aided cases brought by prisoners each year.
(11) Thus, it is obvious that new measures will have to be taken if lives are to be saved in future events of this nature.
(12) While there has been almost no political reform during their terms of office, there have been several ambitious steps forward in terms of environmental policy: anti-desertification campaigns; tree planting; an environmental transparency law; adoption of carbon targets; eco-services compensation; eco accounting; caps on water; lower economic growth targets; the 12th Five-Year Plan; debate and increased monitoring of PM2.5 [fine particulate matter] and huge investments in eco-cities, "clean car" manufacturing, public transport, energy-saving devices and renewable technology.
(13) Considerations on costs and benefits demonstrate that the treatment of severely injured patients, who otherwise would die, results in a considerable social and economic saving (approximately 90 million Swiss francs for the 316 trauma patients analyzed).
(14) As part of the shake-up, the rule that says only half can be saved in cash is being abolished.
(15) Patients treated with ciprofloxacin may need added coverage for anaerobes, but the drug's excellent activity against nosocomial pathogens and its availability in oral form allow for an early change to oral therapy without compromising effectiveness coupled with added savings and convenience.
(16) Given the financial crisis this government inherited, we had no choice but to make significant savings.
(17) To comply with these rules, interest is not paid on Islamic savings or current accounts, or charged on Islamic mortgages.
(18) Essaid Belkalem is live to the danger and saves his side's bacon.
(19) In the lowest prevalence scenario (0.02 initial prevalence), initiation of the program resulted in a projected savings of 2.3 life years per HIV-negative drug user, compared with 1.7 and 1.3 years under medium (0.25) and high (0.60) prevalence, respectively.
(20) He denied that the probation service budget, which has been protected so far from 23% cuts, would be a particular target, but said it was not yet making the same level of savings as was being required of the police.