(n.) The act of accumulating, the state of being accumulated, or that which is accumulated; as, an accumulation of earth, of sand, of evils, of wealth, of honors.
(n.) The concurrence of several titles to the same proof.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(5) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(6) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(7) In addition, the guanosine 3',5'-cyclic monophosphate accumulation response was less impressive in glomeruli than the guanylate cyclase response in IMCD tissue.
(8) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(9) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(10) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(11) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(12) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(13) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
(14) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(15) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(16) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(17) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(18) Accumulating evidence indicates that for most tumors, the switch to the angiogenic phenotype depends upon the outcome of a balance between angiogenic stimulators and angiogenic inhibitors, both of which may be produced by tumor cells and perhaps by certain host cells.
(19) The aim of our experiments was to investigate firstly whether during an acute inflammatory process platelets accumulate in the inflamed area and secondly whether the inflammation has an effect on the properties of the platelets.
(20) The accumulated evidence would strongly favor an affirmative answer.
Backlog
Definition:
(n.) A large stick of wood, forming the back of a fire on the hearth.
Example Sentences:
(1) Backlogs and staff shortages have long been seized upon by veterans groups lobbying for more resources, but it is the apparent cover-up of the scale of the problem that has transformed these latest complaints into a growing political problem for the White House.
(2) Photograph: Rex If they are still unhappy they can go to the free Financial Ombudsman Service (FOS), which resolves disputes between consumers and financial firms, although the PAC raised concerns about the service’s backlog of cases.
(3) More than 95% of this backlog is found in developing countries.
(4) That process could take years given major backlogs in the Italian bureaucracy.
(5) "We should be building 250,000 homes per year just to meet newly arising need, let alone start tackling the backlog, but in England we're currently delivering less than half that amount each year," said Shelter's head of policy and research, Roger Harding.
(6) We present a practical approach to personnel scheduling problems arising in hospital units with demand that is of an urgent nature, cannot be backlogged, and is highly dependent on the time of day.
(7) Tribunal cases against tax cheats should be handled more quickly – many tax cases can take a decade to resolve and the first-tier tribunals have a backlog of 30,000 cases waiting to be heard.
(8) More than 70% of the respondents stated that skilled nursing beds were in short supply in the area served by their facility, while 91% of the respondents reported that their geographic area had a backlog of patients in acute care hospitals awaiting placement in SNFs.
(9) The bank has announced that more than 1,300 branches would also open on the weekend, with some open until 6pm, to deal with the backlog.
(10) Each time the home secretary referred to numbers of extra staff being drafted in to sort out the backlog, there were bellows of "You sacked that many!"
(11) We’ll keep slashing that backlog so our veterans receive the benefits they’ve earned, and our wounded warriors receive the health care – including the mental health care – that they need.
(12) Tim Farron, the Liberal Democrat environment spokesman, called for the government to get "serious" about flooding: "It's clear for anyone to see, that despite their protestations, the government still has a huge backlog of flood relief works in many parts of the country.
(13) However, many thousands have to wait longer than three weeks because of the backlog, so they subsist on the basics and rely on family and friends to help tide them over until the paperwork is complete.
(14) Considering the size of Britain’s infrastructure spending backlog, and the cost of the rail, road and air projects now on the national wishlist, the chancellor’s additional £1.1bn transport spending , with £110m earmarked for the new east-west rail link between Oxford and Cambridge, was perhaps an unambitious amount.
(15) Abbey described the backlog as 'unexpected' and said it was bringing in extra staff to cope.
(16) That backlog has now been cleared to manageable levels.” • In the UK, the Samaritans can be contacted on 08457 90 90 90 or via email: jo@samaritans.org
(17) There should be no more bonuses paid to any senior Home Office managers until the backlogs are cleared.
(18) They have plenty of aspirations for the future, ranging from installing solar cells to building a greenhouse, but, in the meantime, the focus is on tackling the repairs and maintenance backlog.
(19) Improved resources are urgently needed to provide refugees safe and legal routes to sanctuary in Europe and to reunite with family members.” The backlog in asylum procedures meant refugees could be waiting for months until their case was even heard, he said.
(20) At its peak, there was a backlog of more than 100,000 items of post, including 14,800 unopened recorded delivery letters and 13,600 unopened first and second class letters containing crucial information and documents about cases.