(n.) The act of accumulating, the state of being accumulated, or that which is accumulated; as, an accumulation of earth, of sand, of evils, of wealth, of honors.
(n.) The concurrence of several titles to the same proof.
Example Sentences:
(1) The accumulation of lipids and enzymes such as simple estarase, lipase, beta-HDH, alpha-GDH and NADPH-reductase in those areas, suggests that lipids are not a simple excretory product.
(2) After 4 to 6 hours of recirculation, accumulation of vasoactive amine, 5-hydroxytryptamine, its major metabolite, 5-hydroxyindole acetic acid, and its precursor amino acid, tryptophan were detected.
(3) The rate of accumulation of degraded LDL products was lower in collagen gel cultures, but the final levels achieved were the same in the two substrata.
(4) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(5) These effects are similar to those reported for AVP and phorbol esters, activators of protein kinase C. Forskolin and isoproterenol, which induce cAMP accumulation, activated extractable topoisomerase II (maximum 5-15 min after treatment), but not topoisomerase I. Permeable cyclic nucleotide analogs dBcAMP and 8BrcGMP selectively activated extractable topoisomerase II and topoisomerase I activities, respectively.
(6) The data support the conclusion that accumulation of lipid II is responsible in some way for the hypersensitivity of delta rfbA mutants to SDS.
(7) In addition, the guanosine 3',5'-cyclic monophosphate accumulation response was less impressive in glomeruli than the guanylate cyclase response in IMCD tissue.
(8) It was also shown that after a shock at 44 degrees C teratocarcinoma cells were able to accumulate anomalous amounts of hsp 70 despite hsp 70 synthesis inhibition.
(9) At 24 or 48 hours after ischemia, 63Ni, 99TcO4, and 22Na were preferentially concentrated in the damaged striatum and hippocampus, whereas 65Zn, 59Fe, 32PO4, and 147Pm did not accumulate in irreversibly injured tissue.
(10) Aside from these characteristic findings of HCC, it was important to reveal the following features for the diagnosis of well differentiated type of small HCC: variable thickening or distortion of trabecular structure in association with nuclear crowding, acinar formation, selective cytoplasmic accumulation of Mallory bodies, nuclear abnormalities consisting of thickening of nucleolus, hepatic cords in close contact with bile ducts or blood vessels, and hepatocytes growing in a fibrous environment.
(11) They are capable of synthesis and accumulation of glycogen and responsible for its transfer to sites of more intense metabolism (growth, bud, blastema).
(12) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(13) Much information has accumulated on the isolation and characterization of a heterogeneous group of molecules that inhibit one or more of the bioactivities of interleukin 1.
(14) The mechanism by which K+ accumulates in the follicle was insensitive to ouabain, so that a typical Na+, K(+)-ATPase mechanism does not appear to be involved.
(15) The data shows a dissociation between ferritin synthesis, cellular accumulation and secretion for which the mechanisms have still to be elucidated.
(16) The rate of accumulation was highest late in infection and only the slower migrating form incorporates significant amounts of glucosamine.
(17) Initiation of the alternative pathway by the cryptococcal capsule is characterized by a lag in C3 accumulation and the appearance of a limited number of focal initiation sites which resemble those observed when the alternative pathway is activated by zymosan and nonencapsulated cryptococci.
(18) Accumulating evidence indicates that for most tumors, the switch to the angiogenic phenotype depends upon the outcome of a balance between angiogenic stimulators and angiogenic inhibitors, both of which may be produced by tumor cells and perhaps by certain host cells.
(19) The aim of our experiments was to investigate firstly whether during an acute inflammatory process platelets accumulate in the inflamed area and secondly whether the inflammation has an effect on the properties of the platelets.
(20) The accumulated evidence would strongly favor an affirmative answer.
Pile
Definition:
(n.) A hair; hence, the fiber of wool, cotton, and the like; also, the nap when thick or heavy, as of carpeting and velvet.
(n.) A covering of hair or fur.
(n.) The head of an arrow or spear.
(n.) A large stake, or piece of timber, pointed and driven into the earth, as at the bottom of a river, or in a harbor where the ground is soft, for the support of a building, a pier, or other superstructure, or to form a cofferdam, etc.
(n.) One of the ordinaries or subordinaries having the form of a wedge, usually placed palewise, with the broadest end uppermost.
(v. t.) To drive piles into; to fill with piles; to strengthen with piles.
(n.) A mass of things heaped together; a heap; as, a pile of stones; a pile of wood.
(n.) A mass formed in layers; as, a pile of shot.
(n.) A funeral pile; a pyre.
(n.) A large building, or mass of buildings.
(n.) Same as Fagot, n., 2.
(n.) A vertical series of alternate disks of two dissimilar metals, as copper and zinc, laid up with disks of cloth or paper moistened with acid water between them, for producing a current of electricity; -- commonly called Volta's pile, voltaic pile, or galvanic pile.
(n.) The reverse of a coin. See Reverse.
(v. t.) To lay or throw into a pile or heap; to heap up; to collect into a mass; to accumulate; to amass; -- often with up; as, to pile up wood.
(v. t.) To cover with heaps; or in great abundance; to fill or overfill; to load.
Example Sentences:
(1) Electron microscopy revealed the presence of a hitherto unreported peculiar "pilovacuolar" inclusion in numerous mitochondria, composed of an electron dense pile or rod within a vacuole, while globular or crystalline inclusions were absent.
(2) Piling refugees on trains in the hopes that they go far, far away brings back memories of the darkest period of our continent,” he told Der Spiegel.
(3) After the gunfight the marines made the shocking discovery of bodies of 58 men and 14 women in a room, some piled on top of each other.
(4) Chris Williamson, of data provider Markit, said: "A batch of dismal data and a gloomier assessment of the economic outlook has cast a further dark cloud over the UK's economic health, piling pressure on the government to review its fiscal policy and growth strategy.
(5) This is a substantial country, not just a pile of bricks.
(6) Then they become increasingly unable to afford the probation fees that are piled on by private companies paid to oversee them, including fees for everything from basic supervision to drug tests.
(7) For each indicated educational--motivating unity parents have to be completely prepared for better and more complete than usual piling of facts and presenting in front of them unsolvable tasks and obligations.
(8) According to its physical and biochemical properties, poly(L-malate) may alternatively function as a molecular chaperone in nucleosome assembly in the S phase and as both an inhibitor and a stock-piling agent of DNA-polymerase-alpha-primase in the G2 phase and M phase of the plasmodial cell cycle.
(9) You’d think such a spry, successful man would busy himself with other things besides crawling into a pile of stuffed animals to scare his daughter’s date.
(10) In the spare room, there was a pile of CVs aimed at charities to secure this “free labour” imposed by the benefits system.
(11) Vote for me, and I will complete the job of rebalancing it... January 28, 2014 12.03pm GMT Britain's businesses need to stop sitting on their cash piles and crank up their investment, argues IPPR’s chief economist Tony Dolphin: “The news that manufacturing is growing is welcome.
(12) There are 80,000 bars and restaurants there and they're often piled eight stories high on top of each other.
(13) Cards pile on the runs, and here comes Hurdle to get Burnett, about three batters too late.
(14) When my floor was dirty, I rose early, and, setting all my furniture out of doors on the grass, bed and bedstead making but one budget, dashed water on the floor, and sprinkled white sand from the pond on it, and then with a broom scrubbed it clean and white... Further - and this is a stroke of his sensitive, pawky genius - he contemplates his momentarily displaced furniture and the nuance of enchanting strangeness: It was pleasant to see my whole household effects out on the grass, making a little pile like a gypsy's pack, and my three-legged table, from which I did not remove the books and pen and ink, standing amid the pines and hickories ...
(15) Rather, it's because because policymakers and administrators have come to treat higher education as a commercial marketplace, rather than a public trust – and stop-gap student loan reforms like those "unveiled" by President Obama this week fail to confront this ethical dilemma underlying the debt pile.
(16) There is a half-drunk glass of white wine abandoned on the coffee table at his Queensferry home - the Browns had friends around for dinner the previous night - and a stack of children's books and board games piled lopsidedly under a Christmas tree now shedding needles with abandon.
(17) Signs that large companies are ready to start spending some of the cash piles they have been sitting on while smaller firms are prepared to borrow to expand reflect a brighter outlook for sales.
(18) Britain's Serious Fraud Office has launched a formal criminal investigation into GlaxoSmithKline's sales practices, piling further pressure on the drugmaker which is already being investigated by Chinese authorities and elsewhere amid allegations of bribery.
(19) After more than a quarter of a century of camping out, the house, with its seven flights of stairs (a trial to Lessing in her final years), seemed almost to be supported by a precarious interior scaffolding of piles of books and shelves.
(20) The ONS said UK's debt pile had risen to £1.11tn or 70.7% of GDP.