(n.) A unit; a single point or spot on a card or die; the card or die so marked; as, the ace of diamonds.
(n.) Hence: A very small quantity or degree; a particle; an atom; a jot.
Example Sentences:
(1) The serum ACE activity showed no significant difference between male and female in the control or sarcoidosis groups.
(2) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(3) We have studied the effect of chronic ACE inhibition with enalapril on renal structure and function in rats with the two-kidney one-clip model of renovascular hypertension.
(4) In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors.
(5) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(6) We investigated the effects of local angiotensin-converting enzyme (ACE) inhibition by captopril on the autoregulatory efficiency of glomerular blood flow (GBF).
(7) Thus ACE-inhibitors are to be considered for all patients requiring medical therapy for congestive heart failure.
(8) These data indicate that ACE inhibitors are able to unmask a release of bradykinin from cultured human endothelial cells.
(9) However, neither before nor during lisinopril therapy did any changes in urinary protein loss occur during the infusions of Ang II, despite the fact that Ang II reversed the long-term systemic and renal hemodynamic changes induced by the ACE inhibitor.
(10) The mechanisms underlying the positive effects of ACE inhibition and beta-adrenergic blockade are largely unknown, but hemodynamic factors (vasodilation) may contribute by improving the access of glucose and insulin to skeletal muscle.
(11) The choice of antihypertensive drugs in patients with single therapy or combined therapy in the young was beta blockers in 49.7%, Ca blockers in 39.4%, diuretics in 30.7% and ACE inhibitors in 17.8%, and those in the elderly were Ca blockers in 46.1%, diuretics in 44.2%, beta blockers in 33.8%, and ACE inhibitors in 16.4%.
(12) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(13) In the case of somatic ACE, the second equivalent of inhibitor binds to a second zinc-containing site as evidenced by the ability of a moderate excess of inhibitor to protect both zinc ions against dissociation.
(14) ACE inhibition reduces hyperfiltration and is capable of blocking the AA-induced rise in GFR in these patients.
(15) Angiotensin converting enzyme (ACE) is a circulating dipeptidase which has a broad specificity and is known to metabolise a range of circulating peptides.
(16) To assess the degree of the differential ability of serum angiotensin-converting enzyme (ACE) activity as compared with 13 conventional biochemical tests, we studied 76 healthy subjects and 107 patients with chronic liver diseases.
(17) A review of the literature indicated that out of 1087 patients reported, 72 patients were on the combination of an AN69 dialyzer and ACE inhibitor therapy and 41 (57%) demonstrated AR.
(18) It was found that the mean values of serum ACE activity were significantly different between the healthy group and groups with liver disease.
(19) Decreased plasma angiotensin converting enzyme (ACE) activity and increased levels of von Willebrand Factor Antigen (vWF:Ag) were found in all patients with SSc.
(20) In respect of reversal of interstitial fibrosis, ACE inhibitors seem to be effective because the growth of fibroblasts was found to be stimulated by angiotensin II.
Ach
Definition:
(n.) Alt. of Ache
Example Sentences:
(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.