(n.) A unit; a single point or spot on a card or die; the card or die so marked; as, the ace of diamonds.
(n.) Hence: A very small quantity or degree; a particle; an atom; a jot.
Example Sentences:
(1) The serum ACE activity showed no significant difference between male and female in the control or sarcoidosis groups.
(2) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(3) We have studied the effect of chronic ACE inhibition with enalapril on renal structure and function in rats with the two-kidney one-clip model of renovascular hypertension.
(4) In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors.
(5) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(6) We investigated the effects of local angiotensin-converting enzyme (ACE) inhibition by captopril on the autoregulatory efficiency of glomerular blood flow (GBF).
(7) Thus ACE-inhibitors are to be considered for all patients requiring medical therapy for congestive heart failure.
(8) These data indicate that ACE inhibitors are able to unmask a release of bradykinin from cultured human endothelial cells.
(9) However, neither before nor during lisinopril therapy did any changes in urinary protein loss occur during the infusions of Ang II, despite the fact that Ang II reversed the long-term systemic and renal hemodynamic changes induced by the ACE inhibitor.
(10) The mechanisms underlying the positive effects of ACE inhibition and beta-adrenergic blockade are largely unknown, but hemodynamic factors (vasodilation) may contribute by improving the access of glucose and insulin to skeletal muscle.
(11) The choice of antihypertensive drugs in patients with single therapy or combined therapy in the young was beta blockers in 49.7%, Ca blockers in 39.4%, diuretics in 30.7% and ACE inhibitors in 17.8%, and those in the elderly were Ca blockers in 46.1%, diuretics in 44.2%, beta blockers in 33.8%, and ACE inhibitors in 16.4%.
(12) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(13) In the case of somatic ACE, the second equivalent of inhibitor binds to a second zinc-containing site as evidenced by the ability of a moderate excess of inhibitor to protect both zinc ions against dissociation.
(14) ACE inhibition reduces hyperfiltration and is capable of blocking the AA-induced rise in GFR in these patients.
(15) Angiotensin converting enzyme (ACE) is a circulating dipeptidase which has a broad specificity and is known to metabolise a range of circulating peptides.
(16) To assess the degree of the differential ability of serum angiotensin-converting enzyme (ACE) activity as compared with 13 conventional biochemical tests, we studied 76 healthy subjects and 107 patients with chronic liver diseases.
(17) A review of the literature indicated that out of 1087 patients reported, 72 patients were on the combination of an AN69 dialyzer and ACE inhibitor therapy and 41 (57%) demonstrated AR.
(18) It was found that the mean values of serum ACE activity were significantly different between the healthy group and groups with liver disease.
(19) Decreased plasma angiotensin converting enzyme (ACE) activity and increased levels of von Willebrand Factor Antigen (vWF:Ag) were found in all patients with SSc.
(20) In respect of reversal of interstitial fibrosis, ACE inhibitors seem to be effective because the growth of fibroblasts was found to be stimulated by angiotensin II.
Act
Definition:
(n.) That which is done or doing; the exercise of power, or the effect, of which power exerted is the cause; a performance; a deed.
(n.) The result of public deliberation; the decision or determination of a legislative body, council, court of justice, etc.; a decree, edit, law, judgment, resolve, award; as, an act of Parliament, or of Congress.
(n.) A formal solemn writing, expressing that something has been done.
(n.) A performance of part of a play; one of the principal divisions of a play or dramatic work in which a certain definite part of the action is completed.
(n.) A thesis maintained in public, in some English universities, by a candidate for a degree, or to show the proficiency of a student.
(n.) A state of reality or real existence as opposed to a possibility or possible existence.
(n.) Process of doing; action. In act, in the very doing; on the point of (doing).
(v. t.) To move to action; to actuate; to animate.
(v. t.) To perform; to execute; to do.
(v. t.) To perform, as an actor; to represent dramatically on the stage.
(v. t.) To assume the office or character of; to play; to personate; as, to act the hero.
(v. t.) To feign or counterfeit; to simulate.
(v. i.) To exert power; to produce an effect; as, the stomach acts upon food.
(v. i.) To perform actions; to fulfill functions; to put forth energy; to move, as opposed to remaining at rest; to carry into effect a determination of the will.
(v. i.) To behave or conduct, as in morals, private duties, or public offices; to bear or deport one's self; as, we know not why he has acted so.
(v. i.) To perform on the stage; to represent a character.
Example Sentences:
(1) The high amino acid levels in the cells suggest that these cells act as inter-organ transporters and reservoirs of amino acids, they have a different role in their handling and metabolism from those of mammals.
(2) Although Jeggo's Chinese hamster ovary cells were more responsive to mAMSA, novo still abrogated mAMSA toxicity in the mutant cells as well as in the parental Chinese hamster ovary cells 2,4-Dinitrophenol acted similarly to novo with respect to mAMSA killing, but neither compound reduced the ATP content of V79 cells.
(3) administration of the potent short-acting opioid, fentanyl, elicited inhibition of rhythmic spontaneous reflex increases in vesical pressure (VP) evoked by urinary bladder distension.
(4) Family therapists have attempted to convert the acting-out behavioral disorders into an effective state, i.e., make the family aware of their feelings of deprivation by focusing on the aggressive component.
(5) It is suggested that the rapid phase is due to clearance of peptides in the circulation which results in a fall to lower blood concentrations which are sustained by slow release of peptide from binding sites which act as a depot.
(6) Peptides from this region bind to actin, act as mixed inhibitors of the actin-stimulated S1 Mg2(+)-ATPase, and influence the contractile force developed in skinned fibres, whereas peptides flanking this sequence are without effect in our test systems.
(7) Comprehensive regulations are being developed to limit human exposure to contamination in drinking water by the United States Environmental Protection Agency (EPA) under the authority of the Safe Drinking Water Act (SDWA).
(8) Pedigree studies have suggested that there may be an inherited predisposition to many apparently nonfamilial colorectal cancers and a genetic model of tumorigenesis in common colorectal cancer has been proposed that includes the activation of dominantly acting oncogenes and the inactivation of growth suppressor genes.
(9) Propofol is ideal for short periods of care on the ICU, and during weaning when longer acting agents are being eliminated.
(10) We have investigated interactions between the erythroid transcription factor GATA-1 and factors binding two cis-acting elements commonly linked to GATA sites in erythroid control elements.
(11) These later results suggest that dopamine agonists increase sensorimotor reactivity measured with acoustic startle by acting on sensory rather than motor parts of the reflex arc.
(12) Dietary factors affect intestinal P450s markedly--iron restriction rapidly decreased intestinal P450 to beneath detectable values; selenium deficiency acted similarly but was less effective; Brussels sprouts increased intestinal AHH activity 9.8-fold, ECOD activity 3.2-fold, and P450 1.9-fold; fried meat and dietary fat significantly increased intestinal EROD activity; a vitamin A-deficient diet increased, and a vitamin A-rich diet decreased intestinal P450 activities; and excess cholesterol in the diet increased intestinal P450 activity.
(13) It was not clear whether Mn2+ acted at the presynaptic membrane, the postsynaptic membrane or both.
(14) She added: “We will continue to act upon the overwhelming majority view of our shareholders.” The vote was the second year running Ryanair had suffered a rebellion on pay.
(15) In this paper sensitive and selective bioassays are described for growth factors acting on substrate-attached cells, in particular members of the epidermal growth factor, transforming growth factor beta, platelet-derived growth factor, insulin-like growth factor, and heparin-binding growth factor families.
(16) Evidence is presented that the protein can act catalytically.
(17) It was concluded that Ta acts as a weak zeitgeber in laboratory rats and has greater effects on males compared to females.
(18) That’s a criticism echoed by Democrats in the Senate, who issued a report earlier this month criticising Republicans for passing sweeping legislation in July to combat addiction , the Comprehensive Addiction and Recovery Act (Cara), but refusing to fund it.
(19) Tumorigenesis is a multistep process involving mutations of dominantly acting proto-oncogenes and mutations and loss-of-function mutations of tumor suppressor genes.
(20) In one of Pruitt’s first official acts, for example, he overruled the recommendation of his own agency’s scientists, based on years of meticulous research, to ban a pesticide shown to cause nerve damage, one that poses a clear risk to children, farmworkers and rural drinking water supplies.