(n.) A unit; a single point or spot on a card or die; the card or die so marked; as, the ace of diamonds.
(n.) Hence: A very small quantity or degree; a particle; an atom; a jot.
Example Sentences:
(1) The serum ACE activity showed no significant difference between male and female in the control or sarcoidosis groups.
(2) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(3) We have studied the effect of chronic ACE inhibition with enalapril on renal structure and function in rats with the two-kidney one-clip model of renovascular hypertension.
(4) In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors.
(5) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(6) We investigated the effects of local angiotensin-converting enzyme (ACE) inhibition by captopril on the autoregulatory efficiency of glomerular blood flow (GBF).
(7) Thus ACE-inhibitors are to be considered for all patients requiring medical therapy for congestive heart failure.
(8) These data indicate that ACE inhibitors are able to unmask a release of bradykinin from cultured human endothelial cells.
(9) However, neither before nor during lisinopril therapy did any changes in urinary protein loss occur during the infusions of Ang II, despite the fact that Ang II reversed the long-term systemic and renal hemodynamic changes induced by the ACE inhibitor.
(10) The mechanisms underlying the positive effects of ACE inhibition and beta-adrenergic blockade are largely unknown, but hemodynamic factors (vasodilation) may contribute by improving the access of glucose and insulin to skeletal muscle.
(11) The choice of antihypertensive drugs in patients with single therapy or combined therapy in the young was beta blockers in 49.7%, Ca blockers in 39.4%, diuretics in 30.7% and ACE inhibitors in 17.8%, and those in the elderly were Ca blockers in 46.1%, diuretics in 44.2%, beta blockers in 33.8%, and ACE inhibitors in 16.4%.
(12) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(13) In the case of somatic ACE, the second equivalent of inhibitor binds to a second zinc-containing site as evidenced by the ability of a moderate excess of inhibitor to protect both zinc ions against dissociation.
(14) ACE inhibition reduces hyperfiltration and is capable of blocking the AA-induced rise in GFR in these patients.
(15) Angiotensin converting enzyme (ACE) is a circulating dipeptidase which has a broad specificity and is known to metabolise a range of circulating peptides.
(16) To assess the degree of the differential ability of serum angiotensin-converting enzyme (ACE) activity as compared with 13 conventional biochemical tests, we studied 76 healthy subjects and 107 patients with chronic liver diseases.
(17) A review of the literature indicated that out of 1087 patients reported, 72 patients were on the combination of an AN69 dialyzer and ACE inhibitor therapy and 41 (57%) demonstrated AR.
(18) It was found that the mean values of serum ACE activity were significantly different between the healthy group and groups with liver disease.
(19) Decreased plasma angiotensin converting enzyme (ACE) activity and increased levels of von Willebrand Factor Antigen (vWF:Ag) were found in all patients with SSc.
(20) In respect of reversal of interstitial fibrosis, ACE inhibitors seem to be effective because the growth of fibroblasts was found to be stimulated by angiotensin II.
Jot
Definition:
(n.) An iota; a point; a tittle; the smallest particle. Cf. Bit, n.
(v. t.) To set down; to make a brief note of; -- usually followed by down.
Example Sentences:
(1) While Pardew restricted his celebrations to jotting some notes on a pad, a young visiting substitute seated behind him offered a study in unrestrained delight.
(2) 'The Brazilian spectators howled with laughter....' The miss mattered not a jot in terms of qualification.
(3) For several years, Thorn was a full-time parent, not even jotting down lyrics in her notebook.
(4) The idea that Britain is made one jot safer by a £100bn Armageddon weapon floating in the Atlantic is absurd.
(5) Last year, I jotted down several that had me almost salivating at the prospect of buying them.
(6) While Romney speaks, Obama tends to look down at his podium, jotting notes, which doesn't come over too well on television.
(7) White admits that he barely knows more than a paragraph's biography of each of them, but he jotted their names down at various points in the recording process.
(8) It won't help the cause one jot to say this, but for those of us who came of age in the 1960s, here comes our final right to wrest from the old moral and religious orthodoxy: the right to die as we please.
(9) Facebook Twitter Pinterest Fact Kenneth MacMillan was a dab hand with the knitting needle, and would jot down knitting patterns and stitch counts on the same scraps of paper that he used for choreographic notes.
(10) I inform them that I will be turning up with a set of index cards on which I have jotted down key points, but will not be boring my audience to tears with fiddly slides consisting of flying text, fussy fonts or photo montages.
(11) The chap couldn’t recall the name of either of the Scottish leadership contenders and conveyed the distinct impression that, in any case, he cared not a jot.” The response accurately depicts the attitude of the Labour leadership at Westminster to the Scottish party since devolution: “Just send us down your Glasgow and Lanarkshire MPs and keep your mouths shut in the meantime.” Well, as I’m sure they will have noticed by now, Scotland has stopped sending Labour MPs to London… well, apart from wee whatsisname in Edinburgh.
(12) Zoom back in on the past decade and it is clear that for all the mounting scientific concern, the political rhetoric and the clean technology, nothing has made a jot of difference to the long-term trend at the global level – the system level.
(13) It was a war of choice that has killed tens of thousands of people, while not increasing Britain's security one jot.
(14) Such rhetoric is hard to take when the campaign is financed and run in part by people from the Tory party who, going by the current cuts agenda, don't seem to care one jot about public services.
(15) As Mr Cowell and Mr Fuller rattled through their idea for an ambitious new show to identify an unknown British singing star, Boyd scribbled notes on two sides of jotting paper during the hour-long meeting.
(16) "It would have trampled all over the privacy of innocent people without improving our security one jot."
(17) Pfizer's short-term promises about investment in the UK don't matter a jot because the group lives in a perpetual state of reinvention.
(18) To describe his work in progress, he jotted down a list of hyperbolic adjectives: "Astounding, extraordinary, surprising, superhuman, supernatural, unheard of, savage, sinister, formidable, gigantic, savage, colossal, monstrous, deformed, disturbed, electrifying, lugubrious, funereal, hideous, terrifying, shadowy, mysterious, fantastic, nocturnal, crepuscular."
(19) According to this logic, it matters not a jot how you make your money.
(20) The digital age, with its typing and its texting, has left us unable to jot down the simplest of notes with anything like penmanship.