(n.) A unit; a single point or spot on a card or die; the card or die so marked; as, the ace of diamonds.
(n.) Hence: A very small quantity or degree; a particle; an atom; a jot.
Example Sentences:
(1) The serum ACE activity showed no significant difference between male and female in the control or sarcoidosis groups.
(2) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(3) We have studied the effect of chronic ACE inhibition with enalapril on renal structure and function in rats with the two-kidney one-clip model of renovascular hypertension.
(4) In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors.
(5) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(6) We investigated the effects of local angiotensin-converting enzyme (ACE) inhibition by captopril on the autoregulatory efficiency of glomerular blood flow (GBF).
(7) Thus ACE-inhibitors are to be considered for all patients requiring medical therapy for congestive heart failure.
(8) These data indicate that ACE inhibitors are able to unmask a release of bradykinin from cultured human endothelial cells.
(9) However, neither before nor during lisinopril therapy did any changes in urinary protein loss occur during the infusions of Ang II, despite the fact that Ang II reversed the long-term systemic and renal hemodynamic changes induced by the ACE inhibitor.
(10) The mechanisms underlying the positive effects of ACE inhibition and beta-adrenergic blockade are largely unknown, but hemodynamic factors (vasodilation) may contribute by improving the access of glucose and insulin to skeletal muscle.
(11) The choice of antihypertensive drugs in patients with single therapy or combined therapy in the young was beta blockers in 49.7%, Ca blockers in 39.4%, diuretics in 30.7% and ACE inhibitors in 17.8%, and those in the elderly were Ca blockers in 46.1%, diuretics in 44.2%, beta blockers in 33.8%, and ACE inhibitors in 16.4%.
(12) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(13) In the case of somatic ACE, the second equivalent of inhibitor binds to a second zinc-containing site as evidenced by the ability of a moderate excess of inhibitor to protect both zinc ions against dissociation.
(14) ACE inhibition reduces hyperfiltration and is capable of blocking the AA-induced rise in GFR in these patients.
(15) Angiotensin converting enzyme (ACE) is a circulating dipeptidase which has a broad specificity and is known to metabolise a range of circulating peptides.
(16) To assess the degree of the differential ability of serum angiotensin-converting enzyme (ACE) activity as compared with 13 conventional biochemical tests, we studied 76 healthy subjects and 107 patients with chronic liver diseases.
(17) A review of the literature indicated that out of 1087 patients reported, 72 patients were on the combination of an AN69 dialyzer and ACE inhibitor therapy and 41 (57%) demonstrated AR.
(18) It was found that the mean values of serum ACE activity were significantly different between the healthy group and groups with liver disease.
(19) Decreased plasma angiotensin converting enzyme (ACE) activity and increased levels of von Willebrand Factor Antigen (vWF:Ag) were found in all patients with SSc.
(20) In respect of reversal of interstitial fibrosis, ACE inhibitors seem to be effective because the growth of fibroblasts was found to be stimulated by angiotensin II.
Pip
Definition:
(n.) A contagious disease of fowls, characterized by hoarseness, discharge from the nostrils and eyes, and an accumulation of mucus in the mouth, forming a "scale" on the tongue. By some the term pip is restricted to this last symptom, the disease being called roup by them.
(n.) A seed, as of an apple or orange.
(n.) One of the conventional figures or "spots" on playing cards, dominoes, etc.
(v. i.) To cry or chirp, as a chicken; to peep.
Example Sentences:
(1) The D-Phe peptides, which are cleaved especially rapidly by thrombin in water, have structures (in deuterated DMSO) in which the aromatic ring of the D-Phe residue is folded back over the Val or Pip residue.
(2) Each tone pip was presented at four intensity levels (70, 50, 30, and 10 dB hearing threshold level), and graphic recordings were made for each frequency at the specific intensity levels.
(3) Low concentrations of each of the negatively charged phospholipids increased the Vmax., but high ratios of PIP, PIP2 or PA to PC decreased this parameter.
(4) We recorded auditory evoked magnetic fields in response to 128 15 msec duration 1 kHz tone pips from both hemispheres of 6 normal adult males.
(5) Following the complete GSH oxidation diamide impaired the turnover of PIP and PA dramatically.
(6) Each new PIP claim - worth between £21 and £134 a week to disabled claimants - costs an average £182 to administer, compared to £49 under the disability living allowance, said the report.
(7) She admits she "got it wrong" by voting in favour of the Iraq war, a stance exploited by Barack Obama when he pipped the former first lady for the Democratic nomination in 2008.
(8) The precision (coefficient of variation) of the calibration curves for underivatized drugs and their derivatized metabolites over the linear ranges was 2-20% and the reproducibility of the assay over a range of clinical concentrations of these drugs found in human plasma was 5-16% for PANC, 2-4% for VEC and 6-11% for PIP.
(9) A behavioral observation scale (Virginia Polydipsia Scale; VPS) for monitoring drinking patterns was developed and its reliability tested during 25 hours of tandem ratings among six patients with the syndrome of psychosis, intermittent hyponatremia, and polydipsia (PIPS).
(10) By 24 hours pulmonary edema resolved and the PIP and PaO2 returned to baseline.
(11) The thrombin-induced hydrolysis of inositol phospholipids by phospholipase C, which was measured as the formation of [32P]PA, was potentiated by adrenaline, as was the increase in the levels of [32P]PIP2 and [32P]PIP.
(12) Only PIP or TIC + SUL or TAZ were able to inhibit at least 90% of tested strains.
(13) Analysis of twenty-one MP and sixty-eight PIP endoprostheses placed in eighty-three patients until 1979 is given.
(14) A phosphatidylinositol 4-phosphate (PIP) pool linked to muscarinic receptor-activation increased 160% after addition of atropine, the maximal response occurring at a time when relaxation was 80% complete.
(15) We demonstrate for the first time that a number of plasma membrane glycerophospholipids effectively stimulate the ATPase, including PIP, PIP2, and cardiolipin.
(16) Claimants of the benefit that PIP replaced, the very people whom Mr Duncan Smith resigns to defend, were previously at the sharp end of his maladministration.
(17) After two weeks ground squirrels were reanesthetized and tone pips and clicks were delivered through a TDH-49 headphone.
(18) The range of the mean uptake varied considerably between proximal interphalangeal (PIP) joints in normal subjects.
(19) He will himself have to repeatedly reapply for PIP, despite the fact that the severity of his condition meant he was granted a lifelong DLA award, after a paper-based assessment.
(20) The aim was to investigate whether these velocities altered in relation to the peak inflation pressure (PIP) used.