(n.) A unit; a single point or spot on a card or die; the card or die so marked; as, the ace of diamonds.
(n.) Hence: A very small quantity or degree; a particle; an atom; a jot.
Example Sentences:
(1) The serum ACE activity showed no significant difference between male and female in the control or sarcoidosis groups.
(2) At present, ACE inhibitors are preferred because they are usually better tolerated than conventional vasodilators and are clinically more effective.
(3) We have studied the effect of chronic ACE inhibition with enalapril on renal structure and function in rats with the two-kidney one-clip model of renovascular hypertension.
(4) In 33 patients with heart failure (NYHA II-III), the 24-h blood pressure rhythm was examined before and after the titration period of two ACE inhibitors.
(5) In contrast to the intact endothelial monolayers, in homogenates additional kininase activity was found which was not affected by either ACE and NEP inhibitors nor by amastatin and MGTA.
(6) We investigated the effects of local angiotensin-converting enzyme (ACE) inhibition by captopril on the autoregulatory efficiency of glomerular blood flow (GBF).
(7) Thus ACE-inhibitors are to be considered for all patients requiring medical therapy for congestive heart failure.
(8) These data indicate that ACE inhibitors are able to unmask a release of bradykinin from cultured human endothelial cells.
(9) However, neither before nor during lisinopril therapy did any changes in urinary protein loss occur during the infusions of Ang II, despite the fact that Ang II reversed the long-term systemic and renal hemodynamic changes induced by the ACE inhibitor.
(10) The mechanisms underlying the positive effects of ACE inhibition and beta-adrenergic blockade are largely unknown, but hemodynamic factors (vasodilation) may contribute by improving the access of glucose and insulin to skeletal muscle.
(11) The choice of antihypertensive drugs in patients with single therapy or combined therapy in the young was beta blockers in 49.7%, Ca blockers in 39.4%, diuretics in 30.7% and ACE inhibitors in 17.8%, and those in the elderly were Ca blockers in 46.1%, diuretics in 44.2%, beta blockers in 33.8%, and ACE inhibitors in 16.4%.
(12) The effects of the neutral metalloendopeptidase (NEP) inhibitor, thiorphan, and the angiotensin converting enzyme (ACE) inhibitor, captopril, on airway responses to SP5-11 were examined in order to test the hypothesis that differences in degradation of SP and SP5-11 contribute to the difference in airway responsiveness to the two peptides.
(13) In the case of somatic ACE, the second equivalent of inhibitor binds to a second zinc-containing site as evidenced by the ability of a moderate excess of inhibitor to protect both zinc ions against dissociation.
(14) ACE inhibition reduces hyperfiltration and is capable of blocking the AA-induced rise in GFR in these patients.
(15) Angiotensin converting enzyme (ACE) is a circulating dipeptidase which has a broad specificity and is known to metabolise a range of circulating peptides.
(16) To assess the degree of the differential ability of serum angiotensin-converting enzyme (ACE) activity as compared with 13 conventional biochemical tests, we studied 76 healthy subjects and 107 patients with chronic liver diseases.
(17) A review of the literature indicated that out of 1087 patients reported, 72 patients were on the combination of an AN69 dialyzer and ACE inhibitor therapy and 41 (57%) demonstrated AR.
(18) It was found that the mean values of serum ACE activity were significantly different between the healthy group and groups with liver disease.
(19) Decreased plasma angiotensin converting enzyme (ACE) activity and increased levels of von Willebrand Factor Antigen (vWF:Ag) were found in all patients with SSc.
(20) In respect of reversal of interstitial fibrosis, ACE inhibitors seem to be effective because the growth of fibroblasts was found to be stimulated by angiotensin II.
Spade
Definition:
(n.) A hart or stag three years old.
(n.) A castrated man or beast.
(n.) An implement for digging or cutting the ground, consisting usually of an oblong and nearly rectangular blade of iron, with a handle like that of a shovel.
(n.) One of that suit of cards each of which bears one or more figures resembling a spade.
(n.) A cutting instrument used in flensing a whale.
(v. t.) To dig with a spade; to pare off the sward of, as land, with a spade.
Example Sentences:
(1) Time, to use a good Anglo-Saxon expression, to call a spade a spade.
(2) Before you take out your bucket and spade, though, you might like to look at the sand sculpture festival (until 5 September; prices vary from day to day) for inspiration.
(3) The first, the 28A region, gave three recessive lethals and also contains three known visible mutants, spade (spd), Sternopleural (Sp) and wingless (wg); a complex pattern of genetic interaction in the region incorporates both the new and the previously known mutants.
(4) This was greeted by a furious wall of sound from Labour, which only grew when he added: "The last government failed to prioritise compassionate care … they tried to shut down the whistleblowers …" It was pure party-political point-scoring, matched in spades by Labour's Andy Burnham.
(5) The entertainment industry's reliance on the courts for a cheap and dirty fix to all its problems has mutated filesharing into a strain of antibiotic-resistant bacteria that has no one to sue except for individual filesharers (and the most avid music filesharers are also the most avid music everything – CD buyers, concertgoers, bootleg collectors … When you live your life for music, you do everything musical in spades).
(6) Apical hypertrophic cardiomyopathy is characterized by a spade-like left ventricular cavity and by both giant negative T waves and tall R waves in the electrocardiogram.
(7) After one year, attempted removal of the spade tipped K-wire was unsuccessful.
(8) "Any fool can spend money; Gordon Brown has proved that in spades.
(9) Our two cases of trisomy 12p (ter leads to 12.1) were compared with eight cases of trisomy 12p described earlier, and the following common characteristics were found: severe mental and physical retardation; flat and round, broad face with prominent cheeks; flat and broad nasal bridge with short nose; anteverted nostrils and large philtrum; broad and prominent lower lip; low-set or slanting ears, poorly formed with folded helix, prominent antihelix and deep concha; short neck; short sternum; "spade"-shaped fingers, the fifth being short; bilateral genu valgum; bilateral pes planus and talus valgus; increased space between the first and second toes; generalized hypotonia; and certain dermatoglyphic characteristics.
(10) When will spades be called spades and retreats retreats?
(11) Commuting back and forth across the Atlantic has taken its toll but paid off in spades, first with gold and silver in Daegu and now the 10,000m Olympic title.
(12) Little documented, the scene was caught by Colin MacInnes in his 1957 novel City of Spades, whose hero is a West African hustler called Johnny Fortune.
(13) Republicans stake their claim as Christie stresses credentials at CPAC Read more The 2015 Conservative Political Action Conference was in full swing, and at the end of Thursday afternoon, the crowd got what it had come for, in spades: three searing speeches from the main stage razzing President Barack Obama, damning “radical Islamic terrorism” and celebrating the United States as the best place on Earth in history.
(14) These and other problems identified by the PAC apply in spades to mass contracting by CCGs, which are even less capable of managing contracts than central government departments.
(15) Osborne's first spade in the ground was on work at the station for Manchester airport, the UK's third biggest airport.
(16) Another notable Britpop item was the cassingle version of Elastica's Waking Up, designed by Jon Anonymous: made up like a packet of cards, with a spade cut out of the front, it had a band member trading card inside.
(17) The spade-like configuration was also seen in four cases (7.0%) of the GNT- group.
(18) Every reason people in the UK might have not to vote, Nigerians also have, in spades.
(19) Bagolini and Ioli-Spade in 1968 presented a 30 year follow-up on Bietti's cases and presented six additional cases.
(20) In the 9 patients who had cardiac catheterization the left ventricular end-diastolic pressure was raised, and angiography showed an "ace of spades" diastolic image of the left ventricle with systolic obliteration of its tip.