(1) TRP1 RI circle (now designated YARp1, yeast acentric ring plasmid 1) is a 1,453-base-pair artificial plasmid composed exclusively of Saccharomyces cerevisiae chromosomal DNA.
(2) A high correlation between cell killing and number of acentric fragments per cell was found.
(3) Frequencies of induced single- and isochromatid breaks, acentric fragments and interchanges were compared with data obtained from 140 kV X-rays.
(4) The median absolute phase difference for 1811 acentric reflections was 32 degrees.
(5) Acentric fragments were observed associated with about 10% of the bridges.
(6) The subsequent loss of acentric fragments at mitosis is postulated to prevent the continuity of the genome and to produce cell death by the induction of chromatin structural changes.
(7) Dicentric chromosomes were twice more frequent during the entire radiotherapy than acentric fragments and about 30 times more frequent than centric ring chromosomes.
(8) Reductions were also noted in frequency of acentric aberrations.
(9) As a second approach, the number of fluorescence events in the histogram background was corrected for non-chromosomal debris and evaluated interms of chromosome aberration frequency per cell, which was consistent with the yields of dicentric chromosomes and acentric fragments observed in microscopic investigations.
(10) After approximately 3 months in vitro, more than half the cells propagated from rats that developed hepatocellular carcinomas had bean-shaped, acentrically displaced nuclei with large juxtanuclear homogeneous appearing areas resembling the hyalin or Mallory bodies in the livers of chronic alcoholics.
(11) Unstable aberrations were mainly acentric fragments in both groups.
(12) The dose-response of acentric fragment frequency fits a linear model between 0 and 128 R. Thus another cell type is added to those previously demonstrated to have no threshold dose for the induction of chromosome or gene mutations.
(13) The phases of acentric and additional centric reflections were then chosen by adding them to the map with various possible phases and computing the total entropy of the resulting map.
(14) Apparent acentric fragments which replaced a C-group chromosome in cultured blood lymphocytes from a woman patient were shown by autoradiography, G-banding and C-banding to be complete X chromosomes in which the centromere had divided prematurely in relation to the centromeres of other chromosomes in the same metaphase.
(15) Dose-response characteristics and the results of fractionation experiments indicate that the yield of micronuclei reflects both classes of acentric fragments, i.e., those associated and independent of exchange type of aberrations.
(16) A formula, based on the Poisson distribution of radiation-induced chromosomal deletions, was derived to predict the frequency of transmission of acentric fragments between subsequent mitoses.
(17) Each of the markers of 2q+, Dq+, mar(A2, st), mar(C12, M), r(?F) and minute metacentric and acentric markers was observed in two or more patients.
(18) This would have produced a symmetrical isodicentric chromosomes, plus one or two acentric fragments.
(19) Chromosome aberrations such as gaps and breaks of one or both chromatids, acentric fragments, dicentrics, ring chromosomes and other abnormal chromosomes are observed in lymphocyte and fibroblast cultures as well as in direct bone marrow preparations from patients with systemic sclerosis.
(20) The distribution of acentric fragments among mitotic cells conformed to Poisson expectation, while the distribution of micronuclei among daughter cells was significantly overdispersed.
Center
Definition:
(n.) A point equally distant from the extremities of a line, figure, or body, or from all parts of the circumference of a circle; the middle point or place.
(n.) The middle or central portion of anything.
(n.) A principal or important point of concentration; the nucleus around which things are gathered or to which they tend; an object of attention, action, or force; as, a center of attaction.
(n.) The earth.
(n.) Those members of a legislative assembly (as in France) who support the existing government. They sit in the middle of the legislative chamber, opposite the presiding officer, between the conservatives or monarchists, who sit on the right of the speaker, and the radicals or advanced republicans who occupy the seats on his left, See Right, and Left.
(n.) A temporary structure upon which the materials of a vault or arch are supported in position until the work becomes self-supporting.
(n.) One of the two conical steel pins, in a lathe, etc., upon which the work is held, and about which it revolves.
(n.) A conical recess, or indentation, in the end of a shaft or other work, to receive the point of a center, on which the work can turn, as in a lathe.
(v. i.) Alt. of Centre
(v. t.) Alt. of Centre
Example Sentences:
(1) When subjects centered themselves actively, or additionally, contracted trunk flexor or extensor muscles to predetermined levels of activity, no increase in trunk positioning accuracy was found.
(2) Suggested is a carefully prepared system of cycling videocassettes, to effect the dissemination of current medical information from leading medical centers to medical and paramedical people in the "bush".
(3) Of the 138 patients who were admitted to the study, only seventy-one (51 per cent) could be followed for an average of 3.5 years (a typical return rate of urban trauma centers).
(4) Their receptive fields comprise a temporally and spatially linear mechanism (center plus antagonistic surround) that responds to relatively low spatial frequency stimuli, and a temporally nonlinear mechanism, coextensive with the linear mechanism, that--though broad in extent--responds best to high spatial-frequency stimuli.
(5) The study included fifty children, aged six to fourteen years, selected from patients seeking routine dental care at Children's Hospital National Medical Center.
(6) By using these methods, it was clearly indicated that these factors such as TDF of rectum, Z-coordinate of weighted geometric center (WGC-Z), the dose of whole pelvic irradiation, history of chemotherapy and Treponema pallidum hemoagglutination test (TPHA) were important for occurrence of rectal complication.
(7) This paper describes the demographic, clinical, and psychosocial characteristics of a sample of chronically mentally ill clients at a large comprehensive community mental health center.
(8) Cloacal exstrophy, centered on the maldevelopment of the primitive streak mesoderm and cloacal membrane, results in bladder and intestinal exstrophy, omphalocele, gender confusion, and hindgut deformity.
(9) T cells admixed in the germinal centers were overwhelmingly of the T-helper type.
(10) Changing conditions call for each Community Mental Health Center (CMHC) to develop a survival strategy based on its own standards and values.
(11) Of the 385 records reviewed for this study, the majority (87%) received their primary care at community health centers or the hospital's own outpatient clinics.
(12) Radiologic abnormalities included an unusual "moth-eaten" appearance of the markedly short long bones, bizzare ectopic ossification centers, and marked platyspondyly with unusual ossification centers.
(13) The purpose of this study was to determine whether there was a temporal association between the introduction of a Fetal Diagnostic and Treatment Center and changes in fetal mortality.
(14) The lack of TBM prior to germinal center development and their absence in aged mice are inconsistent with the concept that TBM are required for the induction of the germinal center reaction.
(15) Continuity of care programs, such as that developed by the Pain Service of Memorial Sloan-Kettering Cancer Center (New York), with good communication and liaison work between hospital and community, add a much needed dimension to the pain management of these patients in the home.
(16) In contrast, Sca-2 did not appear to stain peripheral T lymphocytes, but recognized only a subset of B lymphocytes which could be localized by immunohistochemistry to germinal centers.
(17) An AT-rich stretch is centered at position -31 with respect to the transcription initiation site, and a potential CCAAT box is centered at position -138.
(18) Patient care data for patients treated at the medical center are first recorded on paper charts and then coded and transferred to computer.
(19) Intrinsic bending of the 527-bp fragment (bend center approximately at bp 240) was represented as a composite of at least two components located near bp 170 and near bp 260.
(20) The shading of the optoelectronic system had a coefficient of variation (CV) of 1.42% for measurements in the center of the displayed area, but a CV of 3.55% for measurements over the whole monitor area.