What's the difference between acetanilide and acetophenetidin?
Acetanilide
Definition:
(n.) A compound of aniline with acetyl, used to allay fever or pain; -- called also antifebrine.
Example Sentences:
(1) Acetanilide levels in plasma determined by the selected ion monitoring method were significantly lower than those measured by spectrophotometry.
(2) A mould which was isolated from a solution of paracetamol was identified as a Penicillium species and was found to possess the ability to utilise a series of substituted acetanilides, including paracetamol (4-hydroxyacetanilide), phenacetin (4-ethoxyacetanilide) and metacetamol (3-hydroxyacetanilide) as sole carbon sources for growth.
(3) The major metabolites of acetanilide are shown not to interfere with these assays and the results suggest the possible presence of a new metabolite of acetanilide.
(4) Oxidate pathways yielded 2,4-diacetylaminophenol (O-demethylation), 5-hydroxy-2,4-diacetylaminoanisole (ring hydroxylation), and 2-methoxy-5-(glycol-amido)acetanilide or its isomer (omega-oxidation).
(5) 2 The results suggest that there is no significant change in hepatic oxidation of acetanilide with age.
(6) The main molecular and catalytic properties of an acetanilide-hydrolyzing enzyme from Pseudomonas acidovorans AE 1, purified to a homogeneous state, were investigated.
(7) Acetanilide hydroxylase (AcOH) activity was measured using an HPLC method with more than 500-fold greater sensitivity than previously described procedures.
(8) The data indicate that, at the doses studied: the primary route of aniline metabolism is via sequential acetylation and hydroxylation, and deacetylation plays a significant role in the disposition of acetanilide.
(9) Alachlor [2-chloro-2',6'-diethyl-N-(methoxymethyl)acetanilide] was determined by hydrolysis to 2,6-diethylaniline with 6N HCl and quantitation of the heptafluorobutyryl derivative by gas chromatography with electron capture detection.
(10) Hydrolysis rates were decreased by various para substitutions of acetanilide.
(11) On the other hand, N-acetates, such as acetanilide and p-acetaminophenol, and no contractile action on the ileum.
(12) A comparative study of the metabolism of [acetyl-14C]phenacetin, [acetyl-14C]methacetin, [acetyl-14C]paracetamol and [acetyl=14C]acetanilide in the rat is reported.
(13) Chloro substitution in the acyl moiety of acetanilide also reduced the rate of hydrolysis.
(14) The structure of the main metabolite of SX-PP 16 (46% of urinary excretion) was elucidated as 3-bromo-4-amino-5-mercapturyl-acetanilid.
(15) Acetanilide with the three hydrogens of the acetyl group replaced by deuterium was administered to 9 human volunteers (50 mg p.o.)
(16) Cells transfected with a pMT2-based vector expressing P450IA2 cDNA (pMT2-IA2) had high acetanilide-4-hydroxylase activity and very low aryl hydrocarbon hydroxylase (AHH) activity.
(17) Acetanilide is a rather specific substrate for RL2, whereas RH1 has the highest specific activity for butanilicaine.
(18) Acetanilides altered the relative cation permeability from Rb (1.25) greater than K (1.0) greater than Cs (0.60) greater than NaequalsLi (0.07) to K (1.0) greater than Rb (0.71) greater than Cs (0.31) greater than NaequalsLi (0.00).
(19) This shift in relative cation permeability is interpreter, in terms of Eisenman's theory of membrane permselectivity, as indicating that acetanilides increase the anionic field strength of the membrane.
(20) The results indicate that Fenclor 64 evoked a "mixed type" induction in virgin as well as in pregnant rabbits since it increased liver weight, cytochrome P-450 levels, as well as p-nitro-anisole-O-demethylase and acetanilide-hydroxylase.