(n.) A volatile liquid consisting of three parts of carbon, six of hydrogen, and one of oxygen; pyroacetic spirit, -- obtained by the distillation of certain acetates, or by the destructive distillation of citric acid, starch, sugar, or gum, with quicklime.
Example Sentences:
(1) On the other hand, immunofluorescence in anterior pituitary cells was faint and detected in only 2 of 28 patients with Graves' disease (7.1%) after absorption of their sera with rat liver aceton powder.
(2) The acetone, pyruvate and alpha-ketoglutarate hydrazone were identified.
(3) Rat heart acid acetone powder was subjected to ion exchange chromatography on CM-cellulose.
(4) The acetone pellet was solubilized using deoxycholate (DOC) and Thy-1.1 was purified by use of a Lens culinaris lectin affinity column and an AcA-34 gel filtration column.
(5) Defatting with acetone as part of the regimen for cutaneous disinfection does not improve microbial removal or reduce the incidence of catheter-related infection, but increases cutaneous inflammation and patient discomfort.
(6) Diffusion coefficients measured on images of water and acetone phantoms were consistent with published values.
(7) Results of H-agglutination inhibition tests demonstrated that SA could not be detected on the flagellin molecule when the flagellar filaments were dissociated to flagellin monomers by heating or treatment with urea, sodium dodecyl sulfate, HCl, or acetone, although SA could be detected on short flagellar fragments obtained by milder heat treatment.
(8) Thus, with elution by either ATP or pyrophosphate, actin has been purified in one step from extracts of acetone-dried muscle powder.
(9) The mechanism suggested leads to photoemissive triplet excited acetone as expected from the cleavage of an intermediate dioxetane.
(10) The vasoactive substance was obtained only by extraction with dichloroacetic acid, hydrochloric acid, and with methylene chloride, but not with aqueous extract, or by ether, ethanol, or acetone extraction.
(11) 1966.-Antibody responses of rabbits to H, O, and Vi antigens did not differentiate vaccine K (acetone-killed and dried) from vaccine L (heat-phenolized and dried) relative to human efficacy.
(12) The fast fraction, isolated and purified by means of cellulose acetate electrophoresis, precipitated in acid acetone and treated with urea 8 M and mercaptoethanol, revealed an anomalous beta chain.
(13) Acetaldehyde and acetone were also detected in the irradiated squalene, which may be formed via a 6-methyl-5-hepten-2-one intermediate.
(14) Amebae were fixed in methanol-formaldehyde or absolute acetone at -15 degrees C before or after stimulation with micromolar cyclic AMP at room temperature (20-25 degrees C).
(15) The kaolin-induced activation of factor XII (XII) to XIIa was studied in plasminogen-free human citrated plasma treated with acetone in the presence of benzamidine 7.5 mM.
(16) Leaching the lyophilized mitochondrial fraction with either hexane or acetone increased substantially the yields of the metabolites.
(17) Urinary immunoreactive LH and FSH were measured in acetone extracts of 3 h collections prior to, during, and immediately after a 3 h infusion of 100 mug LH-RH.
(18) An acid protease from Monascus kaoliang was purified by consecutive applications of fractional acetone precipitation, batchwise CM-cellulose method and DEAE-cellulose column chromatography.
(19) Suspension of acetone powder in Tris-HC1 buffer prepared from brain homogenate also disclosed chemiluminescence to some extent, whereas liposomes made of extracted brain lipid did not.
(20) These findings agree with an earlier Japanese study in showing some mild decrements on behavioural performance tests with exposures to acetone at 250 ppm.
Ketone
Definition:
(n.) One of a large class of organic substances resembling the aldehydes, obtained by the distillation of certain salts of organic acids and consisting of carbonyl (CO) united with two hydrocarbon radicals. In general the ketones are colorless volatile liquids having a pungent ethereal odor.
Example Sentences:
(1) The enzyme was solubilized by Triton X-100 and purified approximately 480-fold by gel filtration and affinity chromatography on alanine methyl ketone-AH-Sepharose 4B.
(2) Urinalysis revealed a low pH, increased ketones and bilirubin excretion, dark yellowish change in color, the appearance of "leaflet-shaped" crystals and increased red blood cells and epithelial cells in the urinary sediment, increased water intake, decreased specific gravity and decreased sodium, potassium and chloride in the urine.
(3) The infusion of sodium acetoacetate resulted in a 10- to 15-fold increase in circulating concentrations of ketone bodies, which were similar in magnitude in normal subjects and diabetic patients.
(4) Results of repeated visual readings spread over three different color blocks for certain concentrations of glucose, ketone, and protein, whereas repeated instrumental readings were never spread greater than two color blocks.
(5) The plasma concentrations of alanine and proline as well as other amino acids increased as the blood ketone body ratio decreased.
(6) Trifluoromethyl ketone dipeptide analogues are good inhibitors of angiotensin converting enzyme.
(7) As a conclusion sec-butanol, probably through its metabolite methyl-ethyl-ketone, is the most potent inducer of microsomal cytochrome P-450 in liver and kidney while iso-butanol does not alter total cytochrome P-450.
(8) A model of increased microvascular permeability pulmonary edema was developed in chronically instrumented unanesthetized sheep using perilla ketone (PK).
(9) Administration of different brain fuels--glucose, mannose, fructose, or the ketone beta-hydroxybutyrate--reduced hippocampal damage induced by coadministration of GCs and either of 2 different neurotoxins (kainic acid and 3-acetylpyridine).
(10) We report the effects of n-alkanols (n-butanol to n-octanol), methyl carboxylic esters (methyl propionate to methyl octanoate) and n-alkyl ketones (2-pentanone to 2-nonanone) on a fast reflex escape response to a mechanical stimulus in Gammarus.
(11) Examination of other potential inhibitors revealed a rank order of potency against calpain to be: peptidyl sulphonium methyl ketones > fluoromethyl ketones, diazomethyl ketones >> acyloxymethyl ketones, an order which differs sharply from that found for cathespin B.
(12) Epigalanthamine, a diastereomer of GAL, was 130-times less potent in vitro in its effect on acetylcholinesterase (AChE) in erythrocytes than the parent compound, and it did not differ significantly from the ketone galanthaminone.
(13) Also, a significant correlation was found between the levels of urine glucose and ketones and the level of acyl carnitine.
(14) This is in contrast to fasting adult dogs, which maintain glucohomeostasis and show only slightly decreased insulin levels, normal glucagon levels and a moderate increase of plasma ketone bodies.
(15) The following processes are discussed in this article: enzyme-catalysed hydrolyses of carboxylic acid esters and amides, phosphate esters, nitriles and epoxides; esterification and inter-esterification reactions catalysed by enzymes; reduction of ketones to secondary alcohols using whole-cell systems or isolated dehydrogenases; oxidation of alicyclic and aromatic substrates using mono-oxygenases and dioxygenases in bacteria and fungi including enzyme-catalysed Baeyer-Villiger oxidations; aldol reactions, formation of optically active cyanohydrins and enzyme-catalysed acyloin type reactions.
(16) The paint base consisted primarily of toluene and methyl ethyl ketone.
(17) Ketonic bodies participate in the power supply of cortex functions of satisfied one-day pigs but their contribution to the nerve tissue power of fasting one-and five-day pigs is insignificant.
(18) Mechanism-based inhibition of myocardial cytosolic calcium-independent phospholipase A2 by Compound 1 was established by demonstrating: 1) time-dependent irreversible inactivation; 2) covalent binding of [3H]Compound 1 to the purified phospholipase A2; 3) ablation of covalent binding of [3H]Compound 1 after chemical inactivation of phospholipase A2 enzymic activity; 4) identical inhibition of myocardial phospholipase A2 by Compound 1 in the absence or presence of nucleophilic scavengers; 5) Compound 1 is a substrate for myocardial calcium-independent phospholipase A2 resulting in the generation of the electrophilic alpha-bromomethyl ketone; 6) phospholipase A2 inhibition requires the in situ generation of the reactive electrophile (i.e.
(19) Inhibition by phenylmethanesulfonyl fluoride and N alpha-p-tosyl-L-lysine chloromethyl ketone indicates the presence of serine and histidine residues in the active center, respectively.
(20) In addition, adrenal S-adenosylmethionine (SAM) and blood ketone bodies were determined Sections of adrenals were evaluated by electron microscopy for histopathological changes.