(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
Debt
Definition:
(n.) That which is due from one person to another, whether money, goods, or services; that which one person is bound to pay to another, or to perform for his benefit; thing owed; obligation; liability.
(n.) A duty neglected or violated; a fault; a sin; a trespass.
(n.) An action at law to recover a certain specified sum of money alleged to be due.
Example Sentences:
(1) In the bars of Antwerp and the cafes of Bruges, the talk is less of Christmas markets and hot chocolate than of the rising cost of financing a national debt which stands at 100% of annual national income.
(2) Madrid now hopes that a growing clamour for future rescues of Europe's banks to be done directly, without money going via governments, may still allow it to avoid accepting loans that would add to an already fast-growing national debt.
(3) Profit for the second quarter was £27.8m before tax but the club’s astronomical debt under the Glazers’ ownership stands at £322.1m, a 6.2% decrease on the 2014 level of £343.4m.
(4) The government did not spell out the need for private holders of bank debt to take any losses – known as haircuts – under its plans but many analysts believe that this position is untenable.
(5) However, civil society groups have raised concerns about the ethics of providing ‘climate loans’ which increase the country’s debt burden.
(6) The pump function of the heart (oxygen debt dynamics), the anaerobic threshold (complex of gas analytical indices), and the efficacy of blood flow in lesser circulation (O2 consumption plateau) were appraised.
(7) In the UK, George Osborne used this to his advantage, claiming "Britain faces the disaster of having its international credit rating downgraded" even after Moody's ranked UK debt as "resilient".
(8) Thus, the decreased hyperemic response after arrest suggests a reduced energetic debt with CSC compared with ARC and may indicate superior myocardial protection with CSC.
(9) It was the ease with which minor debt could slide into a tangle of hunger and despair.
(10) Most (86 percent) had educational debt (mean = $20,500), and more than half of those with debt were making loan payments.
(11) Silvio Berlusconi's government is battling to stay in the eurozone against mounting odds – not least the country's mountain of state debt, which is the largest in the single currency area.
(12) However in a repeat of the current standoff over the federal budget, the conservative wing of the Republican party is threatening to exploit its leverage over raising the debt ceiling to unpick Obama's healthcare reforms.
(13) It would cost their own businesses hundreds of millions of pounds in transaction costs, it would blow a massive hole in their balance of payments, it would leave them having to pick up the entirety of UK debt.
(14) Nevertheless we know that there will remain a large number of borrowers with payday loans who are struggling to cope with their debts, and it is essential that these customers are signposted to free debt advice.
(15) Finally, there is that pesky matter of public debt, which is still 90% of eurozone GDP.
(16) The ONS said it was possible that these one-off items and a rise in tax receipts in January could bring the overall debt figure within the OBR's £80.5bn forecast.
(17) This causes a time lag, with money continuing to be taken until the SLC is made aware that the debt has been settled.
(18) Unsecured lending rose slightly during the month, with outstanding debt increasing by £331m, after contracting by £114m in April.
(19) He said: "Advanced economies are still confronted with high levels of public and private debt, which act as brakes on the recovery.
(20) Portugal's slide towards a Greek-style second bailout accelerated after its principal private lenders indicated that they were growing weary of assurances from Lisbon that it could get on top of the country's debts.