(n.) A name given to several species of plants; as, smallage, wild celery, parsley.
(v. i.) Continued pain, as distinguished from sudden twinges, or spasmodic pain. "Such an ache in my bones."
(v. i.) To suffer pain; to have, or be in, pain, or in continued pain; to be distressed.
Example Sentences:
(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
Acne
Definition:
(n.) A pustular affection of the skin, due to changes in the sebaceous glands.
Example Sentences:
(1) In both cases there was no history of previous trauma and acne.
(2) The mean acne scores, derived from grading and counting lesions and comedones, fell from 63.3 to 6 in the Diane 50 and from 64.2 to 4.5 in the Triphasil group.
(3) However, in GF rats and in rats monoassociated with viable P. acnes, parenteral injection of killed P. acnes antigen inhibited the plaque-forming cell response to sheep erythrocytes.
(4) In deep forms of acne, particularly acne conglobata, Akne-Mycyna may be a valuable supplementation of systemic treatment.
(5) A water based 5% benzoyl peroxide gel (Benzac W5) was compared with topical 1% clindamycin phosphate solution (Cleocin T) in the treatment of acne vulgaris using a randomized, investigator blind study design.
(6) A questionnaire was presented to 2009 18--19 year old military recruitment candidates which enabled assessment of antipathy towards patients with severe acne vulgaris, the occupational handicap associated with severe acne and subjective inhibitions in acne patients.
(7) Clinical severity of acne and sebum excretion decreased significantly at the end of the trial with both drugs, but significantly more with spironolactone.
(8) When we only considered the patients' responses, more of them admitted having had acne than did our controls.
(9) Clindamycin lotion completely suppressed the growth of C acnes organisms, whereas erythromycin and tetracycline did not depress the C acnes counts.
(10) Thirty patients of either sex (23 M, 7 F) ranging in age between 16 and 36 years, affected of acne vulgaris, were given 20% azelaic acid cream over a period of 6 months.
(11) PEC were then collected from mice into which either 100 micrograms of P. acnes or 1 KE of OK-432 had been injected intraperitoneally several times.
(12) Isotretinoin (Accutane Capsules) is a synthetic vitamin A compound used for treatment of recalcitrant cystic acne.
(13) Furthermore, when rats were first immunized and then challenged with active strains of P. acnes, an increased sensitivity to low doses of P. acnes and a chronic exacerbation of inflammation was observed.
(14) All stages were present from acne comedonica to acne conglobata.
(15) The aim of this work is to investigate the anti-comedo activity of 20% azelaic acid cream topically applied in a group of teen-agers affected by acne.
(16) Therefore the prevalence of acne conglobata and acne of at least a moderate degree with cysts and scars was 832,000 for women and 1,319,000 for men 15 to 44 years of age.
(17) Macrophages elicited with thioglycollate and P. acnes displayed enhanced Fn secretory activity when compared with resident unstimulated cells.
(18) Continuous culture studies using a chemostat and varying culture pH showed that highest levels of growth of P. acnes occurred at pH 6.0 and that two clear 'peaks' of histamine production were apparent at pH 4.5 and at pH 7.5.
(19) Skin impurities and fatty hair associated with acne were side effects in 22.5% of 378 patients during the first evaluation and in 10.8% of 369 patients at the second evaluation.
(20) Within 2 months following birth the infants had facial acne and edema, swelling of the eyelids, loss of facial hair including eyelashes, and hyperpigmentation of the skin.