(n.) A name given to several species of plants; as, smallage, wild celery, parsley.
(v. i.) Continued pain, as distinguished from sudden twinges, or spasmodic pain. "Such an ache in my bones."
(v. i.) To suffer pain; to have, or be in, pain, or in continued pain; to be distressed.
Example Sentences:
(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
Depress
Definition:
(v. t.) To press down; to cause to sink; to let fall; to lower; as, to depress the muzzle of a gun; to depress the eyes.
(v. t.) To bring down or humble; to abase, as pride.
(v. t.) To cast a gloom upon; to sadden; as, his spirits were depressed.
(v. t.) To lessen the activity of; to make dull; embarrass, as trade, commerce, etc.
(v. t.) To lessen in price; to cause to decline in value; to cheapen; to depreciate.
(v. t.) To reduce (an equation) in a lower degree.
(a.) Having the middle lower than the border; concave.
Example Sentences:
(1) He's Billy no-mates with a Heckler & Koch sniper-rifle, drowning in loneliness, booze and depression.
(2) Thyroid replacement led to resolution of both apnea and depression.
(3) During and after the infusion of 5HTP, none of the patients showed an increase in anxiety or depressive symptoms, despite the presence of severe side effects.
(4) Sixteen patients in whom schizophrenia was initially diagnosed and who were treated with fluphenazine enanthate or decanoate developed severe depression for a short period after the injection.
(5) Further, at the end of treatment fewer patients had depressive symptoms and the total daily number of hours of wellbeing and normal movement increased.
(6) The active agents modestly improved treadmill exercise duration time until 1 mm ST segment depression (3%), and only propranolol and diltiazem had significant effects.
(7) The ED50 and ED95 of mivacurium in each group were estimated from linear regression plots of log dose vs probit of maximum percentage depression of neuromuscular function.
(8) The data are compared with the results from 79 patients with a bipolar depression, 192 with a neurotic depression and 89 with a depressive reaction.
(9) A similar depressed receptor function was observed for C3b, fibronectin, and some lectins.
(10) From these results, it was suggested that the inhibitory effect of Cd on in vitro calcification of MC3T3-E1 cells may be due to both a depression of cell-mediated calcification and a decrease in physiochemical mineral deposition.
(11) Both treatments depressed nocturnal pineal melatonin content in rats and hamsters.
(12) Infusion of sodium lactate associated with isoproterenol could be used to combat the depressent effects of betablockers in patients with cardiac disorders.
(13) We studied the effects of the localisation and size of ischemic brain infarcts and the influence of potential covariates (gender, age, time since infarction, physical handicap, cognitive impairment, aphasia, cortical atrophy and ventricular size) on 'post-stroke depression'.
(14) The literature on depression and immunity is reviewed and the clinical implications of our findings are discussed.
(15) Subthreshold concentrations of the drug to induce complete blockade (5 x 10(-8)M) allowed to observe a greater depression of bioelectric cell characteristics in primary than in transitional fibres.
(16) However, a recrudescence in both psychotic and depressive symptoms developed as plasma desipramine levels rose 4 times higher than anticipated from the oral doses prescribed.
(17) These results indicate that the hormonal status should be taken into consideration in studies dealing with platelet MAO activity in depressed women.
(18) Three coyotes were operantly conditioned to depress one of two foot treadles, left or right, depending on the condition of the stimulus light.
(19) Although esmolol may be used as a primary hypotensive agent, the potential for marked myocardial depression must be recognized.
(20) Subjects who reported incidents of childhood sexual exploitation had lower levels of self-esteem and higher levels of depression than the comparison group.