What's the difference between ache and displeasure?

Ache


Definition:

  • (n.) A name given to several species of plants; as, smallage, wild celery, parsley.
  • (v. i.) Continued pain, as distinguished from sudden twinges, or spasmodic pain. "Such an ache in my bones."
  • (v. i.) To suffer pain; to have, or be in, pain, or in continued pain; to be distressed.

Example Sentences:

  • (1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
  • (2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
  • (3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
  • (4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
  • (5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
  • (6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
  • (7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
  • (8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
  • (9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
  • (10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
  • (11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
  • (12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
  • (13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
  • (14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
  • (15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
  • (16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
  • (17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
  • (18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
  • (19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
  • (20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.

Displeasure


Definition:

  • (n.) The feeling of one who is displeased; irritation or uneasiness of the mind, occasioned by anything that counteracts desire or command, or which opposes justice or a sense of propriety; disapprobation; dislike; dissatisfaction; disfavor; indignation.
  • (n.) That which displeases; cause of irritation or annoyance; offense; injury.
  • (n.) State of disgrace or disfavor; disfavor.
  • (v. t.) To displease.

Example Sentences:

  • (1) Similarly, throughout the second session, the same stimuli were presented and the subject rated his pleasure or displeasure in response to the second dimension of the matrix (e.g.
  • (2) Richard Dunne clatters into him late, the goalkeeper goes down and several France players swarm around Dunne to voice their displeasure at the Ireland defender.
  • (3) Facebook Twitter Pinterest Benjamin Netanyahu to John Kerry: friends don’t take friends to the security council On Monday, Trump tweeted his displeasure with the UN, dismissing it as “just a club for people to get together, talk and have a good time”.
  • (4) Since snoring is said to be a "disease of listeners," it is not uncommon that bed partners reported an increased incidence of depression and marital displeasure.
  • (5) This minor concession to an "ethical" foreign policy was nevertheless overshadowed by rumours of Tony Blair's displeasure at Cook's action.
  • (6) In a sign of Delhi’s displeasure, work has already stalled on some key Indian-backed development projects in Afghanistan, Spanta claimed.
  • (7) There had been no sign or signal in any way that we had incurred their displeasure.
  • (8) When theRussian host appeared to announce the nation's votes – including seven for Ukraine – the crowd again loudly voiced their displeasure.
  • (9) Chairpeople, on the other hand, have other, more powerful means of expressing their displeasure.
  • (10) The physical and social environment of day care is characterized in terms of its emotional impact with use of three orthogonal dimensions: pleasure-displeasure, arousal-nonarousal, and dominance-submissiveness.
  • (11) Macdonald, who was passed over for a frontbench position post-election and frequently makes his displeasure about that known, has shifted post-budget from recent preoccupations including public opposition to the prime minister’s paid parental leave scheme to arguments about broadening the GST.
  • (12) It signals US displeasure but stops short of a full-blown boycott that could escalate tensions with the Kremlin, at a time when Washington still badly needs Moscow's help on Syria, Iran and other thorny international problems.
  • (13) 1.50pm: an ‘unreserved’ apology on Twitter Less than three hours after his LBC interview, and after a spokesman for Corbyn makes his displeasure clear , Livingstone says he’s sorry – and this time he means it.
  • (14) Many analysts say China is using the meetings with Park to signal its displeasure with North Korea and increase pressure on the government there.
  • (15) Next year, the North will have a lot of demand for economic cooperation projects with China,” Lim said, adding that while Pyongyang may express temporary its displeasure it would soon start working again on improving relations.
  • (16) Such performance could be predicted from the sum of ratings of displeasure aroused in the lower limbs and in the chest.
  • (17) Photograph: Julie Dermansky In Baton Rouge, Louisiana, over 200 people, mostly white, middle-aged males, turned up to show their displeasure with Obama's 23 new executive orders and his attempt to reinstate the assault weapons ban.
  • (18) Coleman described the performance against Serbia as "soul-destroying" and admitted he could have no complaints with the fans who voiced their displeasure.
  • (19) In a game against Marilia, the defender Johnny dos Santos took exception to the referee adding what he considered an inadequate amount of injury time at the end of the game, and expressed his displeasure by karate-kicking the official to the floor .
  • (20) China expressed its displeasure with the Times the day after Barboza's report was published in October.