(n.) A name given to several species of plants; as, smallage, wild celery, parsley.
(v. i.) Continued pain, as distinguished from sudden twinges, or spasmodic pain. "Such an ache in my bones."
(v. i.) To suffer pain; to have, or be in, pain, or in continued pain; to be distressed.
Example Sentences:
(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
Smart
Definition:
(v. i.) To feel a lively, pungent local pain; -- said of some part of the body as the seat of irritation; as, my finger smarts; these wounds smart.
(v. i.) To feel a pungent pain of mind; to feel sharp pain or grief; to suffer; to feel the sting of evil.
(v. t.) To cause a smart in.
(v. i.) Quick, pungent, lively pain; a pricking local pain, as the pain from puncture by nettles.
(v. i.) Severe, pungent pain of mind; pungent grief; as, the smart of affliction.
(v. i.) A fellow who affects smartness, briskness, and vivacity; a dandy.
(v. i.) Smart money (see below).
(v. i.) Causing a smart; pungent; pricking; as, a smart stroke or taste.
(v. i.) Keen; severe; poignant; as, smart pain.
(v. i.) Vigorous; sharp; severe.
(v. i.) Accomplishing, or able to accomplish, results quickly; active; sharp; clever.
(v. i.) Efficient; vigorous; brilliant.
(v. i.) Marked by acuteness or shrewdness; quick in suggestion or reply; vivacious; witty; as, a smart reply; a smart saying.
(v. i.) Pretentious; showy; spruce; as, a smart gown.
(v. i.) Brisk; fresh; as, a smart breeze.
Example Sentences:
(1) Pint from £2.90 The Duke Of York With its smart greige interior, flagstone floor and extensive food menu (not tried), this newcomer feels like a gastropub.
(2) Never become so enamored of your own smarts that you stop signing up for life’s hard classes.
(3) "He's defined by being himself, by being smart, by being a good athlete," Goldwater said of Keller.
(4) Advancing the health and rights of women is the right – and smart – thing to do for any nation hoping to remain or emerge as a leader on the global stage.
(5) By way of encouragement we've got 10 copies of Faber's smart new anniversary edition to give away.
(6) It’s likely Xi’s brand of smart authoritarianism will keep not just his party in power but the whole show on the road If all this were to succeed as intended, western liberal democratic capitalism would have a formidable ideological competitor with worldwide appeal, especially in the developing world.
(7) These letters are also written during a period when Joyce was still smarting from the publishing difficulties of his earlier works Dubliners and A Portrait of the Artist as a Young Man.” Gordon Bowker, Joyce’s biographer, agreed: “Joyce’s problem with the UK printers related to the fact that here in those days printers were as much at risk of prosecution on charges of publishing obscenities as were publishers, and would simply refuse to print them.
(8) I could just banish the app from my phone forever, but deleting a piece of smart tech that makes my life easier doesn’t feel very satisfying.
(9) I buy ‘smart price’, own-brand cornflakes, rather than Kellogg’s, and I still get to the checkout and think, ‘That’s come to a lot again.’” Are you Daniel Blake?
(10) If you're sincere and smart and genuine and lovable that's what's going to come across in your videos and tweets."
(11) In a statement, Fisher Price said: “We recently learned of a security vulnerability with our Fisher-Price WiFi-connected Smart Toy Bear.
(12) Can consoles still survive in a rapidly changing business where smartphones, tablets and smart TVs, and now Steam Machines, are threatening?
(13) Snapchat is also thinking about new devices, launching a Snapchat Micro app for Samsung's Galaxy Gear smart watch in September, capable of shooting pics and videos with the device's camera, then sharing them.
(14) There were signs of encouragement early in the second half from Sunderland, and they should have pulled one back only for a terrible call from the assistant referee Eddie Smart.
(15) In Drosophila melanogaster new tester strains for the somatic mutation and recombination test (SMART) in the wing were constructed with the aim of increasing the metabolic capacity to activate promutagens.
(16) And there are plenty who think that, as our libel laws are cleaned up, smart lawyers are switching horses to privacy.
(17) I think the heart of good comedy really lives in truth and reacting to the absurdities, hypocrisies, abuses of power in the world.” Late night television is a no longer a glass of warm milk before bed, it’s a lunch buffet And as TV viewership declines and internet virality becomes as important as real-time eyeballs, cable networks might find that topical comedy is a smart, cost-effective way to grab cross-platform attention.
(18) With cities moving markets, joint procurement standards generate great potential for economies of scale, from buses to smart street lighting.
(19) A smart city would use IT to manage traffic so air stays fit to breathe.
(20) Pitched as a "smart" calendar, it's easy to create appointments and events, and ties in neatly with the developer's separate Any.do to-do lists app.