(n.) A name given to several species of plants; as, smallage, wild celery, parsley.
(v. i.) Continued pain, as distinguished from sudden twinges, or spasmodic pain. "Such an ache in my bones."
(v. i.) To suffer pain; to have, or be in, pain, or in continued pain; to be distressed.
Example Sentences:
(1) Analysis of conjugated discharges ACHs showed that they appeared predominantly periodically (87% of cases).
(2) By means of two monoclonal antibodies, which were directed against external and internal acetylcholine (ACh) receptor epitopes, we were able to visualize ACh-receptors on OHCs.
(3) At 100 microM-ACh the apparent open time became shorter probably due to channel blockade by ACh molecules.
(4) ACh released from the vesicular fraction was about 100-fold more than could be accounted for by miniature end-plate potentials; possible causes of this overestimate are discussed.
(5) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(6) The response selectivity, such as orientation and direction selectivities, of cortical cells was not affected by the depletion of ACh.
(7) Acetylcholine (ACh) induces a K+ current in rabbit cardiac Purkinje fibres.
(8) This paper examines the chiral nature of the covalent conjugates formed upon reaction of acetylcholinesterase (AchE) with enantiomeric cycloheptyl, isopropyl, and 3,3-dimethylbutyl methylphosphonyl thiocholines.
(9) The results suggest that AH5183 does not bind to the ACh transporter recognition site on the outside of the vesicle membrane, and thus it might inhibit allosterically.
(10) In the absence of prostigmine, increasing the concentration of ACh in the synaptic cleft did not change the time constant for decay of end-plate currents.
(11) We examined the effect of propentofylline on two adenosine actions in the rat hippocampus; the A2-mediated stimulation of 3H-cAMP accumulation and the A1-mediated inhibition of 3H-ACh release.
(12) Neuromuscular transmission and muscle sensitivity to acetylcholine (ACh) were studied in vitro in soleus and extensor digitorium longus (EDL) from 6 hr to 4 months after the injection of toxin.3.
(13) These results suggest that different molecular factors might mediate the effects on GABA and ACh synthesis.
(14) At the adult neuromuscular junction, acetylcholine (ACh) receptors are highly localized at the subsynaptic membrane, whereas, embryonic myotubes before innervation have receptors distributed over the entire surface.
(15) Nitric oxide (NO) induced tetrodotoxin-resistant NANC relaxation, similar to that induced by electrical stimulation or acetylcholine (ACh).
(16) In senescent rats, however, the proportions of salt-soluble and detergent-soluble AChE may differ from those in young rats.
(17) In addition, in these animals blood AChE and butyrylcholine esterase (BuChE) activities were determined.
(18) Roles of the LHA dopaminergic and cholinergic systems in CTS learning were investigated by electrophoretic application of dopamine (DA) and acetylcholine (ACh), and their antagonists.
(19) The absence of ACh therefore appears to reduce the cortical response to stimulation, while background activity values do not change.
(20) As stimulus rate was decreased, blockade of secretion resulted from fewer stimuli but no difference in ACh content was found between stimulated and unstimulated glands.
Spasmodic
Definition:
(a.) Of or pertaining to spasm; consisting in spasm; occuring in, or characterized by, spasms; as, a spasmodic asthma.
(a.) Soon relaxed or exhausted; convulsive; intermittent; as, spasmodic zeal or industry.
(n.) A medicine for spasm.
Example Sentences:
(1) Using a special electromyographic hypodermic needle, we injected botulinum A toxin into one of the vocal folds of two patients with severe spasmodic dysphonia.
(2) These experimental findings suggest that stereotactic thalamotomy of the ventrolateral nucleus for spasmodic torticollis should be performed on the side ipsilateral to the contracting SCM muscle.
(3) The patient (a 46-year-old woman) suffered from a spasmodic quadriplegia, walking was nearly impossible.
(4) 4 ng of botulinum type A toxin per eye were applied in the M. orbicularis oculi as first injection in the 18 patients without spasmodic torticollis.
(5) Spasmodic dysphonia (SD) is a low-incidence voice disorder of unknown origin.
(6) The first case was a young girl of 16 years of age with a lesion at the D6 level and spasmodic paraparesis.
(7) Bilateral TA denervation represents a hopeful new long-term approach to spasmodic dysphonia treatment.
(8) The view emerging is that spasmodic dysphonia is a manifestation of disordered motor control involving systems of neurons rather than single anatomical sites.
(9) Spasmodic attempts were made to relieve the suffering of Yarmouk’s civilians.
(10) To determine the usefulness of EMG-assisted botulinum toxin (BOTOX) injections for the treatment of spasmodic torticollis (ST), we randomized 52 ST patients into two groups and studied them prospectively.
(11) Vestibular findings in a group of 35 patients with spasmodic torticollis without other otological or neurological symptoms were reviewed.
(12) The purpose of this study was to determine whether adolescents with "spasmodic" dysmenorrhea (SD) versus "congestive" dysmenorrhea (CD) respond differently to naproxen sodium therapy.
(13) Further, he maintained that spasmodic constriction of the rectum resulted from dysfunction of this rectosigmoid sphincter.
(14) Of them only 13 (0.26% of the total patient material) were spasmodic bronchitis.
(15) The patient, a 22 year old woman, presented with a three-year history, with clinical onset of staged spinal pain and cervicobrachial neuralgia, of spasmodic paraparesis with sensory and sphincter disturbances.
(16) The first is a hemolysin (100-200,000 mol.wt) which also causes initial spasmodic contractions in larval and adult specimens of Drosophila.
(17) Laser-assisted myomectomy may be a feasible alternative to current methods to treat spasmodic dysphonia.
(18) Paroxysmal cerebellar ataxia (PCA) is a specific disease which exhibits spasmodic cerebellar ataxia but rarely shows abnormal neurological findings in the intermission.
(19) The concept of MVC might be more convincing if MVD can be shown to cure a condition such as spasmodic torticollis, which cannot be remedied by damage to or section of the same cranial nerve or nerves.
(20) The authors describe the anatomical and clinical findings in a case of the pure form of Strümpell Lorrain's familial spasmodic paraplegia.