(v. t.) To make acid; to convert into an acid; as, to acidify sugar.
(v. t.) To sour; to imbitter.
Example Sentences:
(1) All rats were examined in the conscious, unrestrained state 12 wk after induction of diabetes or acidified saline (pH 4.5) injection.
(2) they are shown to inhibit in vitro the release of iron from acidified host cell cytosol, consisting mostly of hemoglobin, a process that could provide this trace element to the parasite.
(3) This report describes the partial purification of an HMW renin from hog kidney extracts which had previously been acidified to pH 2.5.
(4) Hydrogen peroxide (1 mM) acidified pHi but no change occurred with 50 microM.
(5) One group of 6 cats was fed a basal, naturally acidifying diet without added acidifiers, and another group of 6 cats was fed 1.7% dietary phosphoric acid.
(6) The heat-deproteinated extract is acidified to pH 3.5-4 and directly analyzed by LC.
(7) Despite physiological differences, acidified milk replacer can be used successfully to raise Angora kids.
(8) The mean gastric pH of the acidified group was 3.2 compared with the group receiving regular feedings into the stomach (pH = 4.7) and the group receiving regular feedings into the duodenum (pH = 3.8) (p < .01).
(9) Aliquots of 24-h urine collections are acidified and applied to columns of Dowex 50W cation-exchange resin.
(10) Acidified Maalox 70 and Al(OH)3 were significantly more potent than unmodified agents against all four tested types of acute mucosal lesions, and this action was probably due to their 'mild irritant' effect as evidenced by extensive exfoliation of the surface epithelial cells observed microscopically after the exposure of the mucosa to these agents.
(11) Studies using a gastric chamber model demonstrated that sucralfate protected the rat gastric mucosa against hemorrhagic erosions induced by 40 percent ethanol and by acidified 80 mM sodium taurocholate.
(12) Samples are extracted with acidic chloroform, filtered through pre-acidified Hy-Flo Supercel, and cleaned up by acid-base partitioning.
(13) However, an important inhibitory effect in the most acidified fibres, cannot be excluded.
(14) The osteoclasts secrete a large amount of protons by the action of H(+)-pump on the ruffled border into the sealed resorption cavity, resulting in the acidified microenvironment under which condition the bone matrix is dissolved.
(15) With HCO3-CO2 present in the luminal bathing solution alone, proximal colon does not significantly acidify or alkalinize the serosal bathing solution.
(16) Quantitative results down to 2.0 micrograms cm-3 of Al in 0.5-cm-3 acidified samples are readily obtainable in standard 5-mm NMR tubes.
(17) Nigericin, an ionophore which acidifies the cytoplasm when cells are placed in medium at low pHe, was not toxic at pHe 6.5 or above but became very toxic as pHe was reduced below this value.
(18) Similar results were obtained when medium was acidified and chromatographed on Sephadex G-50.
(19) The acidified fetal bovine serum (FBS) produces a factor which inhibits the adipose differentiation of murine fibroblasts 3T3-F442A.
(20) Exposure to CO2 acidifies the cytosol of mitochondria-rich cells in turtle bladder epithelium.
Basify
Definition:
(v. t.) To convert into a salifiable base.
Example Sentences:
(1) The procedure involved extraction of the compounds and the internal standard nitrazepam from basified plasma with dichloromethane and chromatography on a C18 column (microBondapak, 300 X 3.9 mm I.D.)
(2) Reductive destruction of drugs was accomplished by mixing each solution with an equal volume of 1 M potassium hydroxide solution and adding 1 g of nickel-aluminum alloy for each 20 mL of basified solution.
(3) Oxpentifylline, metabolites and internal standards are extracted from basified plasma or urine with chloroform and the metabolites are converted to their O-trifluoroacetates before analysis by capillary gas chromatography using nitrogen-selective detection.
(4) Sufentanil was extracted from basified fluids and tissue homogenates with hexane:ethanol (19:1).
(5) The analytical procedure involved extraction of the compound and its internal standard from basified plasma with n-butyl chloride-dichloromethane and chromatography of the extract on a DB-5 fused-silica column (30 m X 0.25 mm I.D.
(6) Seven major radioactive components were detected in the chloroform extract of basified rat urine and five major components in similar extracts of human urine.
(7) Sulforidazine-5-sulfoxide metabolites were then extracted from the same basified plasma using a second solvent mixture consisting of methylene chloride, pentane and 2-propanol.
(8) Sulforidazine was first extracted from basified plasma using a mixture of pentane and 2-propanol.
(9) The hydrochloric acid phase is basified, and the amphetamines and the internal standard benzylamine are derivatized with pentafluorobenzenesulfonyl chloride prior to analysis on a gas chromatograph equipped with a capillary column.
(10) Tiamenidine and internal standard are extracted from basified plasma, converted to dibenzyl derivatives by reaction with benzyl bromide and potassium t-butoxide in the presence of 18-crown-6 ether prior to analysis by selected ion monitoring.
(11) After addition of the internal standard, plasma samples were basified with phosphate buffer (pH 9.0) and extracted with a mixture of cyclohexane-dichloromethane.
(12) Employing an ethoxy analogue as internal standard, the two compounds were extracted from basified plasma using dichloromethane.
(13) Each organic extract was subsequently back-extracted separately with 0.1 M hydrochloric acid, basified and re-extracted with the original solvent mixtures.
(14) After a single-step extraction from basified samples with dichloromethane, using decarboxyloflazepate as an internal standard, samples were analysed using a reversed-phase Nova Pak 5-microns column with a mobile phase of methanol - phosphate buffer (60 + 40) adjusted to pH 7.6.
(15) DMP is extracted from the plasma after basifying with dichloromethane.
(16) The formation of silver oxide in basified colloids may facilitate borate adsorption.
(17) The organic extract, basified with tetramethylammonium hydroxide, in evaporation tube was evaporated to dryness at 30 degrees C under nitrogen.
(18) The robotic system aliquots the biological sample, adds the internal standard (CGP 23901) and pH 12 buffer, extracts the compounds from the basified matrix into an organic phase (methyl-t-butyl ether:dichloromethane, 2:1) and concentrates the extracts for reversed-phase, high performance liquid chromatographic (HPLC) analysis.
(19) MDL 201,012 (I), diethyl-MDL 201,012 (internal standard, II) and desmethyldiol-MDL 201,012 (masking agent, III) were isolated from basified plasma (2 mL) by solid phase extraction using Bond-Elut C-18 cartridges.
(20) In both techniques, deproteinized and basified plasma samples were extracted and purified by adsorption on an Extrelut-1 column, then the drug was eluted with dichloromethane.