(a.) Consisting of acini, or minute granular concretions; as, acinose or acinous glands.
Example Sentences:
(1) The term tumor was replaced by carcinoma in the following two entities: acinic cell carcinoma and mucoepidermoid carcinoma.
(2) Nine cases identified as acinic cell adenocarcinoma of minor salivary glands from the files of the Armed Forces Institute of Pathology and the Department of Pathology, Temple University School of Dentistry were studied to determine the clinical and histomorphologic parameters of this lesion.
(3) Neuropeptides were observed in the neoplastic epithelial cells of certain tumors such as Warthin's tumors, acinic cell carcinomas, adenocarcinomas and undifferentiated carcinomas.
(4) The prognosis of acinic cell carcinoma and mucoepidermoid carcinoma was much better than that of squamous cell carcinoma, adenocarcinoma and undifferentiated carcinoma.
(5) A preliminary diagnosis of acinic cell carcinoma established by light microscopy was confirmed by electron microscopic study.
(6) A rare case of endomandibular acinic cell carcinoma (ACC) in a white woman aged 79 is reported.
(7) Proteoglycans (PGs) were localised immunohistochemically in 52 salivary gland tumours including pleomorphic adenoma, adenoid cystic carcinoma, acinic cell carcinoma, oncocytoma, mucoepidermoid carcinoma, clear cell tumour and Warthin tumour, using antibodies raised against large PG, small PG, chondroitin 4-sulphate PG, chondroitin 6-sulphate PG, heparan sulphate PG and keratan sulphate PG.
(8) We report a case of isolated cerebral metastasis from an acinic cell carcinoma, which arose in minor salivary glands 20 years previously.
(9) Contrary to the behavior of most acinous cell carcinomas, but similar to the majority of laryngeal adenocarcinomas, the neoplasm herein discussed was extremely aggressive and developed widespread metastases, which led to the patient's death.
(10) Acin-binding protein in the presence of actin causes the actin to form a gel, which liquifies when cooled.
(11) Acinic cell tumors of minor salivary glands are most uncommon.
(12) Grading of these carcinomas may serve to identify subsets whose biologic behavior is more aggressive than the usually accepted low-grade behavior of acinic cell carcinomas as a group.
(13) Mucoepidermoid, acinic cell and most adenocarcinomas were subdivided according to histologic grade and all patients were retrospectively staged according to criteria established by the American Joint Committee on Cancer Staging.
(14) Furthermore, adenoid cystic carcinoma appears to contain a far greater number of myoepithelial cells than acinic cell carcinomas.
(15) Seven malignant tumors of the upper lip were as follows: four adenoid cystic carcinomas, two acinic cell carcinomas, and one adenocarcinoma.
(16) 3) The expression of CK-3, CK-6, CK-7, CK-8 and CK-18 was commonly recognized in both acinal and ductal cells.
(17) Therefore, the clear cells may transform from the neoplastic acinic cells.
(18) Electron microscopy of the aspirated material, however, allowed definite preoperative diagnosis of metastatic acinic cell carcinoma.
(19) The mean numbers of AgNORs in the various tumors were as follows: mucoepidermoid carcinoma, 2.20; acinic cell carcinoma, 2.51; adenoid cystic carcinoma (ACC), 2.57; carcinoma in pleomorphic adenoma, 1.00 (benign component) and 3.99 (cancer-bearing area); salivary duct carcinoma, 4.49; polymorphous low-grade adenocarcinoma, 3.37; sebaceous carcinoma, 2.57; oncocytic carcinoma, 4.63; adenocarcinoma, 4.53.
(20) To our knowledge this is the first report of extraparotid localization of an acinic cell carcinoma in a patient presenting multiple salivary gland tumours.
Acinus
Definition:
(n.) One of the small grains or drupelets which make up some kinds of fruit, as the blackberry, raspberry, etc.
(n.) A grapestone.
(n.) One of the granular masses which constitute a racemose or compound gland, as the pancreas; also, one of the saccular recesses in the lobules of a racemose gland.
Example Sentences:
(1) In castrates, the prostatic stroma became thickened, with a large increase in fibrous material between and surrounding each acinus, although smooth muscle cells retained their normal cytology.
(2) In 60 consecutive patients clinically suspected of having chronic pancreatitis the serum concentration of the immunoglobulins (IgA, IgG, IgM), the IgG- and IgA-type non-organ-specific autoantibodies against nuclear material (ANA), smooth and striated muscle, mitochondria, basal membrane, and reticulin, and the IgG- and IgA-type pancreas-specific antibodies against islet cells, acinus cells, and ductal cells (DA) were estimated blindly.
(3) The summation of findings suggests that endogenous substance P plays a complementary role in the regulation of parasympathetic nerve-induced fluid secretion in the acinus but is minimally involved in degranulation from granular duct cells.
(4) Only a single salivary acinus was found infected in 16.6% of the infected ticks, about 70% had up to 10 infected acini while only about 10% had over 25 infected acini per tick.
(5) These results suggest that functional catalytic activity of cytochrome P-450IIE1 is preferentially localized in the pericentral zone of the liver acinus, and that most of the induction by pyrazole of P-450IIE1 appears to occur within the pericentral zone.
(6) In adult liver there was a heterogeneous distribution of cytochrome P450IA immunoreactivity with cytochrome P450IA mainly present in zone 3 hepatocytes of the liver acinus.
(7) Microdissection studies showed that PKL lost its normal perivenous to periportal gradient after partial hepatectomy and became evenly distributed within the liver acinus.
(8) The development of a new method to isolate hepatocytes originating from the proximal or distal half of the liver acinus enabled the measurement of total cytochrome P-450 content and of cytochromes P-450b and P-450e mRNAs in these hepatocytes.
(9) These results indicated that there is modulation of the expression of the cytochromes P-450b and P-450e genes within the hepatic acinus.
(10) The alveoli in each acinus were reduced in size and, in some cases, number--although their stage of differentiation was normal for age--pointing to a disturbance of growth during later fetal life also.
(11) Monoclonal antibodies against PR and ER were mainly located in the epithelium of the excretory duct and granular convoluted tubule, but not in the acinus.
(12) Clofibrate induced the activities of carnitine acetyltransferase (90-fold), carnitine palmitoyltransferase (3-fold) and NADP-linked malic enzyme (3-fold) to the same level in periportal as in perivenous hepatocytes, suggesting that these enzymes were induced uniformly throughout the liver acinus.
(13) We have optimized a cerium-diaminobenzidine-based method for histochemical analysis of glucose-6-phosphatase (G6Pase) activity and have determined quantitative data on the zonal distribution pattern in the liver acinus of fasted male rats.
(14) Hepatocytes in the perivenous zone immediately adjacent to the hepatic venules in the liver acinus are positive for GS.
(15) The preacinar cells were occasionally observed at the site between acinus and intercalated duct.
(16) Thus, in the intact pancreas, acinar cells intercommunicate extensively within each acinus under resting conditions and reduce their coupling during stimulation.
(17) cells, but the microsomal GST and cytosolic GR were found to be evenly distributed in the acinus.
(18) Numerous micromorphological differences and resemblances between rabbit and cat were found: Acinus 1.
(19) In the mammalian liver the distribution of ammonia-detoxifying enzymes, glutamine synthetase (GS) and carbamoylphosphate synthase I (ammonia) (CPS-I), is mutually exclusive in that these enzymes are expressed in two distinct populations of hepatocytes that are zonally demarcated in the liver acinus.
(20) During their voyage, they traverse the three acinus zones, and since in each they produce different enzymes, each zone represents a differentiation state of the advancing cell.