(1) Astrocyte conditioned medium (ACM) enhanced the survival of neurons and the proliferation of astrocytes in embryonic cortical cultures grown in serum-free defined medium.
(2) Race 4 transconjugants containing avrB0 induced a dark brown necrotic HR within 24 h on the soybean cultivars Harosoy and Norchief, whereas race 4 transconjugants containing avrC induced a light brown necrotic HR within 48 h on the soybean cultivars Acme, Peking, Norchief, and Flambeau.
(3) Posterior fossa decompression with obex plugging (the Gardner operation) was the procedure of choice for SM-ACM and for idiopathic holocord syringomyelia.
(4) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
(5) Material was fixed in buffered-formalin solution and embedded in metacrylate or Durcupan ACM.
(6) In a phase I-II study, 19 patients with acute lymphoid leukemia (ALL) and 8 patients with non-Hodgkin lymphoma (NHL) were given ACM alone according to the regimen designated treatment 1 described above.
(7) The lack of significant abnormalities in post-ictal polysomnograms corresponds to a functional integrity of the brainstem structures involved in the global organization of sleep and may represent a useful laboratory feature in the diagnosis of ACM.
(8) Proliferation of CFU-acm can be controlled by humoral factors and this allows us to conclude that they are not identical to CFUs and probably belong to the compartment of early hemopoietic cells of the granulocyte series.
(9) Sequential studies of the self-limited HgCl2 GN showed that glomerular PCA, proteinuria and glomerular fibrin deposits peaked concomitantly at the acme of the disease, suggesting that immunologically mediated glomerular damage had triggered the extrinsic coagulation pathway.
(10) The ACMS said the mining industry ads ignored the impacts of industrialisation, which it called “the fastest growing threat to the reef”.
(11) Conversely, the exposure of cells to the anthracycline compounds at 0 degree C resulted in almost complete disappearance of cell kill effects except with ACM; ACM retained substantial cell kill effects even at the given low temperature.
(12) With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
(13) These data lead us to conclude that ACM-DOX association partly reverses the DOX resistance at clinically achievable concentrations.
(14) The significance of these observations was discussed in terms of possible interactions at the level of ACM and CAF biotransformation and the potential for interactions of CAF with other xenobiotics.
(15) That triumphal speech was his apex, the acme, the zenith of his career.
(16) The therapeutic value of these compounds for established ACME remains uncertain.
(17) The structural basis of this bleeding disorder has been further assessed by studying the interaction of the following Val(12)-substituted human fibrinogen-like peptides with bovine thrombin in aqueous solution by use of two-dimensional NMR spectroscopy (including TRNOE): Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala- Glu-Val(12)-Gly-Gly-Val-Arg(16)-Gly(17)-Pro-Arg-Val-NH2 (F16), Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16) (tF16), Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16)-Gly(17)-Pro-Arg-Val-Cys(Acm)-NH2 (F17), and Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly- Val-Arg(16) (tF17).
(18) A sensitive enzyme immunoassay method (EIA) for an anticancer drug, aclacinomycin A (ACM), has been developed.
(19) A comparison of the ACM aa sequence with the aa sequences of other proteins in the NBRF data base reveals that ACM has strong similarity to the N-O-diacetylmuramidase secreted by the fungus Chalaropsis.
(20) None of the 8 patients suffering from ovarial cancer benefitted from ACM therapy.
Apogee
Definition:
(n.) That point in the orbit of the moon which is at the greatest distance from the earth.
(n.) Fig.: The farthest or highest point; culmination.
Example Sentences:
(1) The apogee, for me, is his book Terra Nullius , a 2005 Australia travelogue that indicts Britons and white Australians for terrible abuses such as the transportation of Aborigine women to the chillingly named Isle of the Dead where they were given inappropriate and often fatal syphilis treatment, and the extensive forced separation of "half-blood" children from their families to prison-like camps.
(2) From a test flight perspective, I’m less focused on the apogee, although the outside world is focused on the apogee.
(3) All this reached its apogee in 1987, with the sleeve art for Pink Floyd's A Momentary Lapse of Reason .
(4) A well pad sits only a couple hundred feet from Apogee Stadium, home of the university’s Mean Green football team.
(5) Whitesides’ comments two weeks ago made it clear that thermal protection, and not the height – or apogee – reached by the craft, was his main concern.
(6) For Britons reared on the Churchillian narrative, for Americans who crossed the Atlantic to save Europe from Nazi barbarism, for Russians who see the defeat of Hitler as their finest moment, and most of all, for Jews to whom the Holocaust represents the apogee of evil, Ozols' position may seem perverse.
(7) It has been found that in the mature female carp in the pre-spawning period with the light periods being long (L:D = 16:8) the apogee for gonadotropin occurs 10 hr after the onset of the light period.
(8) Michael Jackson dead was the scoop of a lifetime for any media outlet, and the apogee of the four-year-old celebrity-obsessed site that boasts its snippets are "even more fascinating than the hype".
(9) Conservative ideas of fairness are sometimes cast as "fair dues"; the success of David Davis, son of a single parent raised on a council estate, is cited as its apogee.
(10) Onset of labor data revealed a diurnal distribution with an apogee at midnight to 2 AM and a nadir at 11 AM to noon.
(11) The apogee of this feeling came in the summer with the release of Burn (a track first written for the X Factor winner Leona Lewis).
(12) So it's probably worth noting at this stage that people have been declaring episodic storytelling, mixed voices and unreliable narrators as the apogee of innovation at least since Achaemenides told Aeneas about Polyphemus.
(13) There were two steroid peaks between the LH apogees.
(14) Built in the 1560, the gigantic mausoleum is an example of a great tomb-building tradition which reached its apogee 100 years later with the Taj Mahal.
(15) Immediate, transient pressor responses occurred in 94 per cent followed by a more gradual sustained change in blood pressure reaching an apogee in about 20 minutes.
(16) The choices thereafter are many – you are close to the ridge and the Spanish border – but that spring is the apogee of the walk.
(17) While the Disney film is set at the apogee of empire – "The year is 1910, it's the age of men" crowed David Tomlinson as Mr Banks – Travers's book is firmly located in the 1930s, Auden's "low, dishonest decade".
(18) The hourly means of ionized calcium and phosphorus demonstrate significant diurnal variation with a similar apogee, nadir, and periodicity (24 hours).
(19) Nobody wants, and, in particular, nobody wants to pay for, a restoration of the Swedish welfare state at its apogee.
(20) To a gathered crowd of onlookers, Otis ascended into the air on his platform, then, at the apogee, had an assistant cut the rope with a dagger.