What's the difference between acme and crisis?

Acme


Definition:

  • (n.) The top or highest point; the culmination.
  • (n.) The crisis or height of a disease.
  • (n.) Mature age; full bloom of life.

Example Sentences:

  • (1) Astrocyte conditioned medium (ACM) enhanced the survival of neurons and the proliferation of astrocytes in embryonic cortical cultures grown in serum-free defined medium.
  • (2) Race 4 transconjugants containing avrB0 induced a dark brown necrotic HR within 24 h on the soybean cultivars Harosoy and Norchief, whereas race 4 transconjugants containing avrC induced a light brown necrotic HR within 48 h on the soybean cultivars Acme, Peking, Norchief, and Flambeau.
  • (3) Posterior fossa decompression with obex plugging (the Gardner operation) was the procedure of choice for SM-ACM and for idiopathic holocord syringomyelia.
  • (4) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
  • (5) Material was fixed in buffered-formalin solution and embedded in metacrylate or Durcupan ACM.
  • (6) In a phase I-II study, 19 patients with acute lymphoid leukemia (ALL) and 8 patients with non-Hodgkin lymphoma (NHL) were given ACM alone according to the regimen designated treatment 1 described above.
  • (7) The lack of significant abnormalities in post-ictal polysomnograms corresponds to a functional integrity of the brainstem structures involved in the global organization of sleep and may represent a useful laboratory feature in the diagnosis of ACM.
  • (8) Proliferation of CFU-acm can be controlled by humoral factors and this allows us to conclude that they are not identical to CFUs and probably belong to the compartment of early hemopoietic cells of the granulocyte series.
  • (9) Sequential studies of the self-limited HgCl2 GN showed that glomerular PCA, proteinuria and glomerular fibrin deposits peaked concomitantly at the acme of the disease, suggesting that immunologically mediated glomerular damage had triggered the extrinsic coagulation pathway.
  • (10) The ACMS said the mining industry ads ignored the impacts of industrialisation, which it called “the fastest growing threat to the reef”.
  • (11) Conversely, the exposure of cells to the anthracycline compounds at 0 degree C resulted in almost complete disappearance of cell kill effects except with ACM; ACM retained substantial cell kill effects even at the given low temperature.
  • (12) With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
  • (13) These data lead us to conclude that ACM-DOX association partly reverses the DOX resistance at clinically achievable concentrations.
  • (14) The significance of these observations was discussed in terms of possible interactions at the level of ACM and CAF biotransformation and the potential for interactions of CAF with other xenobiotics.
  • (15) That triumphal speech was his apex, the acme, the zenith of his career.
  • (16) The therapeutic value of these compounds for established ACME remains uncertain.
  • (17) The structural basis of this bleeding disorder has been further assessed by studying the interaction of the following Val(12)-substituted human fibrinogen-like peptides with bovine thrombin in aqueous solution by use of two-dimensional NMR spectroscopy (including TRNOE): Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala- Glu-Val(12)-Gly-Gly-Val-Arg(16)-Gly(17)-Pro-Arg-Val-NH2 (F16), Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16) (tF16), Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16)-Gly(17)-Pro-Arg-Val-Cys(Acm)-NH2 (F17), and Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly- Val-Arg(16) (tF17).
  • (18) A sensitive enzyme immunoassay method (EIA) for an anticancer drug, aclacinomycin A (ACM), has been developed.
  • (19) A comparison of the ACM aa sequence with the aa sequences of other proteins in the NBRF data base reveals that ACM has strong similarity to the N-O-diacetylmuramidase secreted by the fungus Chalaropsis.
  • (20) None of the 8 patients suffering from ovarial cancer benefitted from ACM therapy.

Crisis


Definition:

  • (n.) The point of time when it is to be decided whether any affair or course of action must go on, or be modified or terminate; the decisive moment; the turning point.
  • (n.) That change in a disease which indicates whether the result is to be recovery or death; sometimes, also, a striking change of symptoms attended by an outward manifestation, as by an eruption or sweat.

Example Sentences:

  • (1) The playing fields on which all those players began their journeys have been underfunded for years and are now facing a renewed crisis because of cuts to local authority budgets.
  • (2) 2010 2 May : In a move that signals the start of the eurozone crisis, Greece is bailed out for the first time , after eurozone finance ministers agree to grant the country rescue loans worth €110bn (£84bn).
  • (3) An unexpected result of the Greek crisis has been a flight of capital into British government bonds, which has seen gilt prices fall.
  • (4) The ophthalmic headache's crisis is caused, in fact, by a spasm of convergence on an unknown exophory of which the amplitude of fusion is satisfying, and the presence of which can only be seen with test under screen.
  • (5) Recognition and prompt treatment of this potentially fatal dermatological crisis is stressed.
  • (6) Aldi, Lidl and Morrisons are to raise the price they pay their suppliers for milk, bowing to growing pressure from dairy farmers who say the industry is in crisis.
  • (7) Five of the children presented an "aplastic crisis," for example, a sudden decrease in hemoglobin concentration associated with absence of reticulocytes in the peripheral blood, and four were admitted with unremitting severe pain because of a "vaso-occlusive crisis."
  • (8) It added that the crisis had highlighted significant weaknesses in financial regulation, with further measures needed to strengthen supervision.
  • (9) The headteacher of the school featured in the reality television series Educating Essex has described using his own money to buy a winter coat for a boy whose parents could not afford one, in a symptom of an escalating economic crisis that has seen the number of pupils in the area taking home food parcels triple in a year.
  • (10) On Monday, the day after a party congress officially cementing Putin's candidacy in the 4 March presidential election, the top stories on Inosmi concerned modernisation, the eurozone crisis and Iran.
  • (11) A patient with autoimmune hemolytic anemia of the warm antibody type developed a hyperacute hemolytic crisis with acute renal failure under conventional treatment with corticosteroids.
  • (12) "Emerging markets are slowing down from pre-crisis growth rates.
  • (13) Four patients developed an hypertensive crisis with quite elevated levels of aldosterone, cortisol and plasma renin activity.
  • (14) For a union that, in less than 25 years, has had to cope with the end of the cold war, the expansion from 12 to 28 members, the struggle to create a single currency and, most recently, the eurozone crisis, such a claim risks accusations of hyperbole.
  • (15) That was how the similar crisis in Sangatte in 2002 was eventually dealt with .
  • (16) The legs of that argument were cut off by the financial crisis.
  • (17) Given the financial crisis this government inherited, we had no choice but to make significant savings.
  • (18) But mention the words "eurozone crisis" to other Finns, and you could be rewarded with little more than a confused, albeit friendly, smile.
  • (19) The sources were two adolescent patients with sickle cell disease and aplastic crisis who had unsuspected parvovirus infection.
  • (20) Tony Abbott urges Europe to adopt Australian policies in refugee crisis Read more Given that Obama – whatever one’s views on his strategy – is not advocating a bigger military contribution, the only difference is that Abbott is “urging” the US and others to do more, which sounds resolute, and Turnbull says he would consider any request if it was made.