(1) Astrocyte conditioned medium (ACM) enhanced the survival of neurons and the proliferation of astrocytes in embryonic cortical cultures grown in serum-free defined medium.
(2) Race 4 transconjugants containing avrB0 induced a dark brown necrotic HR within 24 h on the soybean cultivars Harosoy and Norchief, whereas race 4 transconjugants containing avrC induced a light brown necrotic HR within 48 h on the soybean cultivars Acme, Peking, Norchief, and Flambeau.
(3) Posterior fossa decompression with obex plugging (the Gardner operation) was the procedure of choice for SM-ACM and for idiopathic holocord syringomyelia.
(4) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
(5) Material was fixed in buffered-formalin solution and embedded in metacrylate or Durcupan ACM.
(6) In a phase I-II study, 19 patients with acute lymphoid leukemia (ALL) and 8 patients with non-Hodgkin lymphoma (NHL) were given ACM alone according to the regimen designated treatment 1 described above.
(7) The lack of significant abnormalities in post-ictal polysomnograms corresponds to a functional integrity of the brainstem structures involved in the global organization of sleep and may represent a useful laboratory feature in the diagnosis of ACM.
(8) Proliferation of CFU-acm can be controlled by humoral factors and this allows us to conclude that they are not identical to CFUs and probably belong to the compartment of early hemopoietic cells of the granulocyte series.
(9) Sequential studies of the self-limited HgCl2 GN showed that glomerular PCA, proteinuria and glomerular fibrin deposits peaked concomitantly at the acme of the disease, suggesting that immunologically mediated glomerular damage had triggered the extrinsic coagulation pathway.
(10) The ACMS said the mining industry ads ignored the impacts of industrialisation, which it called “the fastest growing threat to the reef”.
(11) Conversely, the exposure of cells to the anthracycline compounds at 0 degree C resulted in almost complete disappearance of cell kill effects except with ACM; ACM retained substantial cell kill effects even at the given low temperature.
(12) With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
(13) These data lead us to conclude that ACM-DOX association partly reverses the DOX resistance at clinically achievable concentrations.
(14) The significance of these observations was discussed in terms of possible interactions at the level of ACM and CAF biotransformation and the potential for interactions of CAF with other xenobiotics.
(15) That triumphal speech was his apex, the acme, the zenith of his career.
(16) The therapeutic value of these compounds for established ACME remains uncertain.
(17) The structural basis of this bleeding disorder has been further assessed by studying the interaction of the following Val(12)-substituted human fibrinogen-like peptides with bovine thrombin in aqueous solution by use of two-dimensional NMR spectroscopy (including TRNOE): Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala- Glu-Val(12)-Gly-Gly-Val-Arg(16)-Gly(17)-Pro-Arg-Val-NH2 (F16), Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16) (tF16), Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16)-Gly(17)-Pro-Arg-Val-Cys(Acm)-NH2 (F17), and Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly- Val-Arg(16) (tF17).
(18) A sensitive enzyme immunoassay method (EIA) for an anticancer drug, aclacinomycin A (ACM), has been developed.
(19) A comparison of the ACM aa sequence with the aa sequences of other proteins in the NBRF data base reveals that ACM has strong similarity to the N-O-diacetylmuramidase secreted by the fungus Chalaropsis.
(20) None of the 8 patients suffering from ovarial cancer benefitted from ACM therapy.
Peak
Definition:
(n.) A point; the sharp end or top of anything that terminates in a point; as, the peak, or front, of a cap.
(n.) The top, or one of the tops, of a hill, mountain, or range, ending in a point; often, the whole hill or mountain, esp. when isolated; as, the Peak of Teneriffe.
(n.) The upper aftermost corner of a fore-and-aft sail; -- used in many combinations; as, peak-halyards, peak-brails, etc.
(n.) The narrow part of a vessel's bow, or the hold within it.
(n.) The extremity of an anchor fluke; the bill.
(v. i.) To rise or extend into a peak or point; to form, or appear as, a peak.
(v. i.) To acquire sharpness of figure or features; hence, to look thin or sicky.
(v. i.) To pry; to peep slyly.
(v. t.) To raise to a position perpendicular, or more nearly so; as, to peak oars, to hold them upright; to peak a gaff or yard, to set it nearer the perpendicular.
Example Sentences:
(1) The coefficient of variation in the integrated area of a single peak is 16%.
(2) Here we show that this induction of AP-2 mRNA is at the level of transcription and is transient, reaching a peak 48-72 hr after the addition of RA and declining thereafter, even in the continuous presence of RA.
(3) Amino acid sequence analysis showed that both peaks had identical N-terminal sequences through the first 28 residues.
(4) These observations were confirmed by the killing curves in pooled serum obtained at peak and trough levels.
(5) The peak molecular weight never reached that of a complete 2:1 complex.
(6) Peak Expiratory Flow and Forced Expiratory Mean Flows in the ranges 0-25%, 25-50% and 50-75% of Forced Vital Capacity were significantly reduced in animals exposed to gasoline exhaust fumes, whereas the group exposed to ethanol exhaust fumes did not differ from the control group.
(7) We’re learning to store peak power in all kinds of ways: a California auction for new power supply was won by a company that uses extra solar energy to freeze ice, which then melts during the day to supply power.
(8) No significant correlations of peak VO2 were observed between the 3 tests.
(9) Peaks in the sperm index were preceded by 6 days with peaks in the serum testosterone concentration.
(10) Peak incidence is found among 40 to 49-year-old and 60 to 64-year-old women.
(11) The remainder of the radioactivity appeared chromatographically just prior to the bisantrene peak, indicating that compounds more polar than the parent were present as transformation products.
(12) The curve of mitoses peaked at the same time as that of TK activity but was only 68% as extensive.
(13) We conclude that the rat somatosympathetic reflex consists of an early excitatory component due to the early activation of RVL-spinal sympathoexcitatory neurons with rapidly conducting axons and a later peak that may arise from the late activation of these same neurons as well as the early activation of RVL vasomotor neurons with more slowly conducting spinal axons.
(14) The ACTH deficiency recovered spontaneously, with normal cortisol responses to depot Synacthen (greater than 1380 at 6 h) and hypoglycemia (peak, 590) 14 and 18 months postpartum, respectively.
(15) No relationship was found with the absolute value of either peak or area GH.
(16) GnRH infusion produced an immediate increase in plasma LH concentrations in the mares that ovulated during the infusion period and LH levels peaked at the time of ovulation.
(17) In guinea pig ventricular myocytes, the positive contractile staircase was associated with ascending staircases of both peak systolic and end diastolic [Ca2+]i because of a cumulative increase in diastolic [Ca2+]i.
(18) A considerably greater increase in the peak plasma OT concentration resulted when hungry foster litters of 6 pups were suckled after the mothers' own 6 pups had been suckled.
(19) The incidence was 0.31 per 1000 gynaecological admissions and the peak age incidence was in the age group 26 to 35 years.
(20) A relative net reduction of 47% in lactose malabsorption was produced by adding food, and the peak-rise in breath H2 was delayed by 2 hours.