What's the difference between acme and summit?

Acme


Definition:

  • (n.) The top or highest point; the culmination.
  • (n.) The crisis or height of a disease.
  • (n.) Mature age; full bloom of life.

Example Sentences:

  • (1) Astrocyte conditioned medium (ACM) enhanced the survival of neurons and the proliferation of astrocytes in embryonic cortical cultures grown in serum-free defined medium.
  • (2) Race 4 transconjugants containing avrB0 induced a dark brown necrotic HR within 24 h on the soybean cultivars Harosoy and Norchief, whereas race 4 transconjugants containing avrC induced a light brown necrotic HR within 48 h on the soybean cultivars Acme, Peking, Norchief, and Flambeau.
  • (3) Posterior fossa decompression with obex plugging (the Gardner operation) was the procedure of choice for SM-ACM and for idiopathic holocord syringomyelia.
  • (4) A variety of protected peptides up to tetradecapeptides have been chromatographed at pressures of 50 to 150 psi and obtained in analytically pure from within 2 to 4 h. With such commonly used protecting groups as N-benzyloxycarbonyl (Z), N-2-(p-biphenylyl)-2-propyloxycarbonyl (Bpoc), N-t-butyloxycarbonyl (Boc), O- and S-t-butyl (But), and S-acetamidomethyl (Acm), compounds were sufficiently soluble in chloroform, alcohols, acetic acid, or mixtures of these solvents for column loading.
  • (5) Material was fixed in buffered-formalin solution and embedded in metacrylate or Durcupan ACM.
  • (6) In a phase I-II study, 19 patients with acute lymphoid leukemia (ALL) and 8 patients with non-Hodgkin lymphoma (NHL) were given ACM alone according to the regimen designated treatment 1 described above.
  • (7) The lack of significant abnormalities in post-ictal polysomnograms corresponds to a functional integrity of the brainstem structures involved in the global organization of sleep and may represent a useful laboratory feature in the diagnosis of ACM.
  • (8) Proliferation of CFU-acm can be controlled by humoral factors and this allows us to conclude that they are not identical to CFUs and probably belong to the compartment of early hemopoietic cells of the granulocyte series.
  • (9) Sequential studies of the self-limited HgCl2 GN showed that glomerular PCA, proteinuria and glomerular fibrin deposits peaked concomitantly at the acme of the disease, suggesting that immunologically mediated glomerular damage had triggered the extrinsic coagulation pathway.
  • (10) The ACMS said the mining industry ads ignored the impacts of industrialisation, which it called “the fastest growing threat to the reef”.
  • (11) Conversely, the exposure of cells to the anthracycline compounds at 0 degree C resulted in almost complete disappearance of cell kill effects except with ACM; ACM retained substantial cell kill effects even at the given low temperature.
  • (12) With the MM cells, hyperthermia potentiated the cytotoxic effects of doxorubicin (ADM), daunorubicin, mitoxantrone (DHAD), and quelamycin but did not enhance that of aclacinomycin (ACM).
  • (13) These data lead us to conclude that ACM-DOX association partly reverses the DOX resistance at clinically achievable concentrations.
  • (14) The significance of these observations was discussed in terms of possible interactions at the level of ACM and CAF biotransformation and the potential for interactions of CAF with other xenobiotics.
  • (15) That triumphal speech was his apex, the acme, the zenith of his career.
  • (16) The therapeutic value of these compounds for established ACME remains uncertain.
  • (17) The structural basis of this bleeding disorder has been further assessed by studying the interaction of the following Val(12)-substituted human fibrinogen-like peptides with bovine thrombin in aqueous solution by use of two-dimensional NMR spectroscopy (including TRNOE): Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala- Glu-Val(12)-Gly-Gly-Val-Arg(16)-Gly(17)-Pro-Arg-Val-NH2 (F16), Ala-Asp-Ser-Gly-Glu-Gly-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16) (tF16), Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly-Val- Arg(16)-Gly(17)-Pro-Arg-Val-Cys(Acm)-NH2 (F17), and Ala-Asp-Ser-Gly-Glu-Cys(Acm)-Asp(7)-Phe-Leu-Ala-Glu-Val(12)-Gly-Gly- Val-Arg(16) (tF17).
  • (18) A sensitive enzyme immunoassay method (EIA) for an anticancer drug, aclacinomycin A (ACM), has been developed.
  • (19) A comparison of the ACM aa sequence with the aa sequences of other proteins in the NBRF data base reveals that ACM has strong similarity to the N-O-diacetylmuramidase secreted by the fungus Chalaropsis.
  • (20) None of the 8 patients suffering from ovarial cancer benefitted from ACM therapy.

Summit


Definition:

  • (n.) The top; the highest point.
  • (n.) The highest degree; the utmost elevation; the acme; as, the summit of human fame.
  • (n.) The most elevated part of a bivalve shell, or the part in which the hinge is situated.

Example Sentences:

  • (1) David Cameron last night hit out at his fellow world leaders after the G8 dropped the promise to meet the historic aid commitments made at Gleneagles in 2005 from this year's summit communique.
  • (2) Blood samples were collected from an antecubital vein at sea level (S1), in a base camp at 1515 m prior to the summit ascent (S2), on the summit at 3285 m after 6.5 hours of climbing (S3), at base camp immediately after the descent (S4), and at sea level following a trail descent from the base camp (S5).
  • (3) Herman Van Rompuy, the European Council president chairing the summit, hoped to finesse an overall agreement on the banking supervisor.
  • (4) Gordon Brown believes that the fact of the G20 summit has persuaded many tax havens, such as Switzerland and Liechtenstein, to indicate that they will adopt a more open approach.
  • (5) If you want to become a summit celebrity be sure to strike a pose whenever you see the ENB photographer approaching.
  • (6) The green fund contributions already announced (which include a $3bn pledge by the US and a $1.5bn pledge by Japan revealed during the G20 summit) “show very clearly that if we want the emerging countries and the more fragile countries to participate in this global growth, we have to ... support them,” Hollande said.
  • (7) The World Humanitarian Summit in May 2016 may be the most timely opportunity to make an honest appraisal of the effectiveness of the current system to deal with the sector’s “ new normal ” of finite resources and unlimited challenges.
  • (8) The work group, which will include Home Office representatives and other officials on the UK side, will meet before a White House summit on the issue next month.
  • (9) The agreement, hailed as a "landmark" deal and a breakthrough by politicians and the green lobby alike, came before a crucial EU summit opening in Brussels tomorrow at which 27 prime ministers and presidents are supposed to finalise an ambitious package to cut greenhouse gas emissions by 20% by 2020.
  • (10) It won't be worth putting away his travel bags after returning from Perth as the G20 summit in Cannes, France, beckons.
  • (11) Moscovici added that France wants the summit to set up a eurozone banking union, which would take on responsibility for propping up failing banks and guarantee depositors' savings across the 17 countries.
  • (12) The Rio+ 20 Earth summit could collapse after countries failed to agree on acceptable language just two weeks before 120 world leaders arrive at the biggest UN summit ever organised, WWF warned on Wednesday.
  • (13) Today, three years after the 2012 London summit, our partnership is stronger than ever.
  • (14) The Australian prime minister and the Russian president discussed the Malaysia Airlines tragedy during a 15-minute meeting on the sidelines of the Asia Pacific Economic Cooperation (Apec) summit on Tuesday.
  • (15) It’s not like we’re pushing our way in here,” said CEO Doug McMillon during this week’s sustainability summit at company headquarters in Bentonville, Arkansas.
  • (16) Talking ahead of a UN climate summit in Peru next month, Kim said he was alarmed by World Bank-commissioned research from the Potsdam Institute for Climate Impact Research in Germany, which said that as a result of past greenhouse gas emissions the world is condemned to unprecedented weather events.
  • (17) If you are the company deploying those technologies, there’s a massive opportunity.” A separate survey released earlier this week by the global accountability system CDP gives a more upbeat picture of business opinion regarding the Paris summit.
  • (18) After the Italian prime minister, Matteo Renzi, threatened to veto a deal with Turkey, a reference to media freedom was added to the final summit statement.
  • (19) The vast majority of members would rather have a quiet body, offering technical assistance here and there and convening an occasional summit.
  • (20) The home secretary, Theresa May, will attend a summit in Washington on tackling violent extremism, called by Barack Obama after the Charlie Hebdo murders in Paris.