(1) The typical features of acrocephaly and symmetrical syndactyly were seen.
(2) Apert (1906) was the first to identify a syndrome characterized by the association of acrocephaly with syndactyly, acrocephalosyndactylism.
(3) A newborn boy presented with an acrocephaly characterized by a coronal craniosynostoses, open sagittal sutures and abnormally high and straight forehead.
(4) Developmental delay was not pronounced in the patient's mother or sister; craniofacial characteristics at variance with the characteristic description included acrocephaly and maxillary prominence.
(5) Acrocephalosyndactyly (Apert syndrome) is a rare craniosynostotic syndrome characterized by acrocephaly, syndactyly of the hands and feet, and--occasionally--conductive hearing loss.
(6) A family is described in which 15 persons in five generations are affected with a complex of skeletal malformations which variably includes peculiar asymmetric facies, delayed closure of large fontanels, brachycephaly, acrocephaly, brachydactyly, cutaneous syndactyly, broad great toes, and mild shortness of stature.
(7) They were characterized as follows: cerebral maldevelopment, dwarfism and cataracts (autosomal recessive inheritance); cerebral maldevelopment, dwarfism and facial osteoproliferation (autosomal recessive inheritance); cerebral maldevelopment and colobomata (autosomal recessive inheritance); and cerebral maldevelopment and acrocephaly (X-linked recessive inheritance).
(8) The diagnosis was based on the clinical appearance (phenotype) showing acrocephaly and syndactyly of both hands and feet, supported by skull roentgenography and ultrasonography.
(9) In 1969, Herrmann and Opitz described a syndrome of acrocephaly, oligosyndactyly, hypertelorism, and mental retardation.
(10) Two sisters born to consanguineous parents had a syndrome of short stature, acrocephaly, hypertelorism, proptosis, ptosis, down-slanting palpebral fissures, high nose bridge and anteverted nares, short philtrum, cleft palate, micrognathia, abnormal external ears, preauricular pits, sensorineural and conductive deafness, proximally placed first toes and digitalized thumbs, bulbous digits, metatarsus adductus, and pectus excavatum.
(11) They had acrocephaly, hypertelorism, antimongoloid slant of the palpebral fissures, protrusion of the eyes, large and broad nose, small mandible, irregularly placed teeth, additional upper canine, high-arched palate, partial syndactyly of fingers and toes, brachydactyly of toes, valgus deformity of hypertrophied triangular great toes, broad phalanges of the great toes and broad first metatarsals, accessory epiphyses lateral to the interphalangeal joint of the great toes, and normal intelligence.
(12) On the cranial deformities, 7 cases of scaphocephaly, 4 cases of oxycephaly and 3 cases of acrocephaly were diagnosed.
(13) Distinctive features present in all 6 children include microcephaly, acrocephaly, prominent forehead, flat facial profile, depressed nasal bridge, flat malar areas, "carp" mouth, micrognathia and mental retardation.
(14) Report of a boy aged 16 years with LEBER's congenital amaurosis, which is associated with typical nystagmus and further severe general retardation, including ossification, imbecillity, acrocephaly, dysraphia and cardiomyopathia.
(15) Agenesis of the corpus callosum and malformation of limbic structures are described in a patient with Apert syndrome, a disorder characterized by acrocephaly, severe syndactyly, and often, mental retardation.
(16) The syndrome consists of acrocephaly, soft tissue syndactyly, brachy- or agenesis mesophalangy of the hands and feet, preaxial polydactyly, congenital heart disease, mental retardation, hypogenitalism, obesity, and umbilical hernia.
Pointed
Definition:
(imp. & p. p.) of Point
(a.) Sharp; having a sharp point; as, a pointed rock.
(a.) Characterized by sharpness, directness, or pithiness of expression; terse; epigrammatic; especially, directed to a particular person or thing.
Example Sentences:
(1) Single-case experimental designs are presented and discussed from several points of view: Historical antecedents, assessment of the dependent variable, internal and external validity and pre-experimental vs experimental single-case designs.
(2) Well tolerated from the clinical and laboratory points of view, it proved remarkably effective.
(3) We are pursuing legal action because there are still so many unanswered questions about the viability of Shenhua’s proposed koala plan and it seems at this point the plan does not guarantee the survival of the estimated 262 koalas currently living where Shenhua wants to put its mine,” said Ranclaud.
(4) She knows you can’t force the opposition to submit to your point of view.
(5) The isoelectric points (pI) of E1 and E2 for all VEE strains studied were approx.
(6) Ofcom will conduct research, such as mystery shopping, to assess the transparency of contractual information given to customers by providers at the point of sale".
(7) Fifty-two pairs of canine femora were tested to failure in four-point bending.
(8) A one point dilution enzyme-linked immunosorbent assay (ELISA) procedure suitable for determining immunoglobulin G (IgG) antibody levels to Toxoplasma gondii (T. gondii) in community seroepidemiological surveys is described.
(9) Subsequent isoelectric focusing in sucrose revealed an isoelectric point of 9.0-9.2.
(10) Gross deformity, point tenderness and decrease in supination and pronation movements of the forearm were the best predictors of bony injury.
(11) Whole-virus vaccines prepared by Merck Sharp and Dohme (West Point, Pa.) and Merrell-National Laboratories (Cincinnati, Ohio) and subunit vaccines prepared by Parke, Davis and Company (Detroit, Mich.) and Wyeth Laboratories (Philadelphia, Pa.) were given intramuscularly in concentrations of 800, 400, or 200 chick cell-agglutinating units per dose.
(12) A Monte Carlo simulation was performed to characterize the spatial and energy distribution of bremsstrahlung radiation from beta point sources important to radioimmunotherapy (RIT).
(13) From the social economic point of view nosocomial infections represent a very important cost factor, which could be reduced to great deal by activities for prevention of nosocomial infection.
(14) He said Germany was Russia’s most important economic partner, and pointed out that 35% of German gas originated in Russia.
(15) Many examples are given to demonstrate the applications of these programs, and special emphasis has been laid on the problem of treating a point in tissue with different doses per fraction on alternate treatment days.
(16) In 11 of the 22 cells PAI-1 mRNA and in 6 of the 22 cells PAI-2 mRNA was found, pointing to a possible role of plasminogen activator inhibitors in the tumor-related plasminogen activator activity.
(17) Sequence specific binding of protein extracts from 13 different yeast species to three oligonucleotide probes and two points mutants derived from Saccharomyces cerevisiae DNA binding proteins were tested using mobility shift assays.
(18) Recent studies point to the involvement of regulatory peptides in diseases of the gut and lung.
(19) The positive predictive accuracy of a biophysical profile score of 0, with mortality and morbidity used as end points, was 100%.
(20) The starting point is the idea that the current system, because it works against biodiversity but fails to increase productivity, is broken.