(n.) Chronic enlargement of the extremities and face.
Example Sentences:
(1) The changes in cell mass, body fat and extracellular water observed in acromegaly suggest different dose-response relationships between GH and these parameters.
(2) Biochemical evaluation demonstrated characteristic changes typical of acromegaly, and an unusual pattern of delayed somatotropin response to hGHRH40, not previously described in this syndrome.
(3) We have attempted to investigate a relationship between the paradoxical GH secretion with the abnormal glucose tolerance test present in some cases of acromegaly.
(4) Body composition determination by bioelectrical impedance analysis (BIA) has been compared with measurement of total body water (TBW) by tritiated water dilution and estimation of body fat (BF) by measurement of TBW and total body potassium (TBK) in a four-compartment model, in patients with acromegaly.
(5) Thus, lack of response to exogenous GHRH in untreated acromegaly may indicate the presence of an ectopic GHRH producing tumor.
(6) Immunoreactive digoxin-like substance was determined in 52 subjects: 17 healthy ones, 15 patients with essential hypertension, 10 cases of chronic renal failure and 10 patients with acromegaly.
(7) In this situation, insulin binding at low hormone concentrations was further reduced to one-half of that in the control group, and the sensitivity of insulin-induced antilipolysis was markedly decreased in acromegaly.
(8) Ectopic GHRH is a relatively uncommon cause of acromegaly, which should be differentiated from pituitary adenoma, in order to avoid damage to the pituitary gland from unnecessary interventions.
(9) At the pituitary level, it has been shown that the number of binding sites was negatively correlated to growth hormone levels in acromegaly.
(10) We measured 695 sera obtained in short stature children (GH deficiency or normal GH secretory) and adults (normal, hypopituitarism or acromegaly).
(11) Acromegaly is caused by GH-secreting pituitary adenomas and, in rare cases, by ectopic production of GRH with resultant hypersecretion of GH.
(12) We conjecture that postmenopausal and involutional osteoporosis were far advanced before the development of acromegaly, explaining the coexistence of the two conditions.
(13) In conclusion, SMS is a useful clinical tool for treatment of acromegaly, and a multiple sc injection method seems to be preferable.
(14) A patient with acromegaly was shown to have obstructive sleep apnoea by polygraphic recordings.
(15) A young woman presented with acromegaly and amenorrhea-galactorrhea with hypersomatotropinemia and hyperprolactinemia.
(16) The authors report 3 cases of acromegaly diagnosed while the patients were in hospital for cardiovascular disease: arterial hypertension in two and hypertrophic myocardiopathy in all three.
(17) Serum-prolactin concentrations were measured in 111 patients who had radiological abnormalities of the pituitary but no evidence of acromegaly, Cushing's syndrome, or Nelson's syndrome.
(18) There was no difference in diastolic function between patients with active acromegaly and those with treated acromegaly.
(19) The increased risk of colon cancer in acromegaly is consistent with previous clinical reports and suggests opportunities for etiologic research and early cancer detection.
(20) We have observed an apparent hypoglobulinemia in 17 of 35 patients (48.6%) with acromegaly.
Gland
Definition:
(n.) An organ for secreting something to be used in, or eliminated from, the body; as, the sebaceous glands of the skin; the salivary glands of the mouth.
(n.) An organ or part which resembles a secreting, or true, gland, as the ductless, lymphatic, pineal, and pituitary glands, the functions of which are very imperfectly known.
(n.) A special organ of plants, usually minute and globular, which often secretes some kind of resinous, gummy, or aromatic product.
(n.) Any very small prominence.
(n.) The movable part of a stuffing box by which the packing is compressed; -- sometimes called a follower. See Illust. of Stuffing box, under Stuffing.
(n.) The crosspiece of a bayonet clutch.
Example Sentences:
(1) Five of the nine normal livers had peribiliary glands that showed HLA-DR.
(2) Intestinal glands are not observed until 8.5cm, and are shallow in depth even in the adult.
(3) Our results show that large complex lipid bodies and extensive accumulations of glycogen are valuable indicators of a functionally suppressed chief cell in atrophic parathyroid glands.
(4) In this study, pinealectomy did not alter the inhibitory effect of testosterone on neuroendocine-gonadal activity in the male rat, suggesting that the pineal gland does not mediate the response of the rat hypothalamic-pituitary axis to testosterone.
(5) The epithelium of Brunner's gland stained intensely with Ricinus communis agglutinin-I (RCA-I), succinylated-WGA (S-WGA) and wheat-germ agglutinin (WGA), moderately with Bandeirea simplicifolia agglutinin-I (BS-I), Concanavalia ensiformis agglutinin (Con A) peanut agglutinin (PNA) and Ulex europaeus agglutinin-I (UEA-I) and occasionally with Dolichos biflorus agglutinin (DBA), Lens culinaris agglutinin (LCA) and soybean agglutinin (SBA).
(6) On the basis of obtained data on the uniformity of chemical compounds of the secretion of glands belonging to different groups their common origin has been suggested.
(7) When labelled long-chain fatty acids or glycerol were infused into the lactating goat, there was extensive transfer of radioactivity into milk in spite of the absence of net uptake of substrate by the mammary gland.
(8) Only methoxyindole acetic acid was detectable after incubation of unstimulated and alpha-adrenergic-agonist-treated pineal glands.
(9) The nature of the putative autoantigen in Graves' ophthalmopathy (Go) remains an enigma but the sequence similarity between thyroglobulin (Tg) and acetylcholinesterase (ACHE) provides a rationale for epitopes which are common to the thyroid gland and the eye orbit.
(10) An in vitro bioassay was used to examine [14C]glucose incorporation into polysaccharides in albumen glands (AGs) of susceptible M-line Biomphalaria glabrata infected with the NMRI strain of Schistosoma mansoni.
(11) During the development of Shvets' leukosis, the weight of spleen and lymph glands and their lymphocyte content change enormously while the number of plasmocytes rises exponentially.
(12) Between the 24th and 29th day mature daughter sporocysts with fully developed cercariae ready to emerge, or already emerged, could be seen in the digestive gland of the snail.
(13) The bursa of Fabricius, thymus glands and spleen of chickens were also shown to express mRNA coding for ANP.
(14) Accordingly, the present studies were conducted to determine whether acute OVX-induced FSH hypersecretion can be elicited in an animal model in which the anterior pituitary gland is isolated from diencephalic chemical signals, and if so, whether the hypersecretion could be abated by the FSH-suppressing protein, follistatin.
(15) Light microscopy of both apneics and snorers revealed mucous gland hypertrophy with ductal dilation and focal squamous metaplasia, disruption of muscle bundles by infiltrating mucous glands, focal atrophy of muscle fibers, and extensive edema of the lamina propria with vascular dilation.
(16) Following the study of total lipid and phospholipid contents of Harderian gland, we carried out analysis of glycolipid fractions.
(17) Exogenous rIL-2 restored T-cell proliferation only in the salivary gland cultures of this patient.
(18) In the univariate life-table analysis, recurrence-free survival was significantly related to age, pTNM category, tumour size, presence of certain growth patterns, tumour necrosis, tumour infiltration in surrounding thyroid tissue and thyroid gland capsule, lymph node metastases, presence of extra-nodal tumour growth and number of positive lymph nodes, whereas only tumour diameter, thyroid gland capsular infiltration and presence of extra-nodal tumour growth remained as significant prognostic factors in the multivariate analysis.
(19) Striated muscle fibres were found in each of twenty consecutive pineal glands cultured from individual neonatal rats.2.
(20) Type C-like particles were found inter- and intracellularly in gland and vessel lumina and scattered in the connective tissue.