(a.) Sharp at the end; ending in a sharp point; pointed; -- opposed to blunt or obtuse; as, an acute angle; an acute leaf.
(a.) Having nice discernment; perceiving or using minute distinctions; penetrating; clever; shrewd; -- opposed to dull or stupid; as, an acute observer; acute remarks, or reasoning.
(a.) Having nice or quick sensibility; susceptible to slight impressions; acting keenly on the senses; sharp; keen; intense; as, a man of acute eyesight, hearing, or feeling; acute pain or pleasure.
(a.) High, or shrill, in respect to some other sound; -- opposed to grave or low; as, an acute tone or accent.
(a.) Attended with symptoms of some degree of severity, and coming speedily to a crisis; -- opposed to chronic; as, an acute disease.
(v. t.) To give an acute sound to; as, he acutes his rising inflection too much.
Example Sentences:
(1) In January 2011, the Nobel peace prize laureate was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection .
(2) It is concluded that acute renal denervation augments the pressure diuresis that follows carotid occlusion.
(3) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
(4) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(5) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(7) After a period on fat-rich diet the patient's physical fitness was increased and the recovery period after the acute load was shorter.
(8) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
(9) The results suggest that RPE cannot be used reliably as a surrogate for direct pulse measurement in exercise training of persons with acute dysvascular amputations.
(10) Statistically significant differences were found mainly in the randomized trial, where during the first and second years, respectively, adenoidectomy subjects had 47% and 37% less time with otitis media than control subjects and 28% and 35% fewer suppurative (acute) episodes than control subjects.
(11) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(12) During the procedure, acute respiratory failure developed as a result of tracheal obstruction.
(13) Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case.
(14) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(15) The acute effect of alcohol manifested itself by decreasing mitochondrial respiration, compensated by increased glycolytic activity of the myocardium so that myocardial energy phosphate concentration remained unchanged.
(16) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.
(17) The younger patients more often experienced an acute arthritis with sacroiliitis resembling a reactive disease.
(18) All five individuals appeared to have acute C. pneumoniae infection as determined by results of serologic tests (titers of IgM antibody for all individuals were greater than or equal to 1:16).
(19) The results clearly show that the acute hyperthermia of unrestrained rats induced by either peripheral or central injections of morphine is not caused by activation of the pituitary-adrenal axis.
(20) The effect of hypertension, hyperlipidemia, and the combination of both on acute and chronic myocardial ischemia were evaluated in a total of 30 male rabbits.
Ague
Definition:
(n.) An acute fever.
(n.) An intermittent fever, attended by alternate cold and hot fits.
(n.) The cold fit or rigor of the intermittent fever; as, fever and ague.
(n.) A chill, or state of shaking, as with cold.
(v. t.) To strike with an ague, or with a cold fit.
Example Sentences:
(1) Aspartylglycosaminuria (AGU) is a hereditary metabolic disorder characterized by slowly progressive mental deterioration from infancy, urinary excretion of large amounts of aspartylglycosamine, and decreased activity of the lysosomal enzyme aspartylglcosamine amido hydrolase in various body tissues and fluids.
(2) Correlated morphological and biochemical studies thus definitely establish that AGU is a generalized storage disorder.
(3) Aspartylglucosaminuria (AGU) is a lysosomal storage disease due to mutations in the aspartylglucosaminidase (AGA) gene.
(4) The polymerase chain reaction was used to amplify the glycosylasparaginase protein coding sequence from the three AGU patients in order to compare them to the normal sequence from a full-length human placenta cDNA clone HPAsn.6 (Fisher, K.J., Tollersrud, O.K., and Aronson, N.N., Jr. (1990) FEBS Lett.
(5) The addition of Ser AGC AGU tRNA to an E. coli cell-free protein synthesizing system which contains the endogenous tRNA levels results in up to 100% of the ribosomes translating the MS2 coat gene shifting into the -1 reading frame.
(6) Thus, the high prevalence of AGU in the Finnish population is the consequence of a founder effect of one ancient mutation.
(7) When the 3' overlapping codon is AGA or AGG, there is no ribosome frameshifting; when it is AGU (read by the same serine tRNA) there is frameshifting, although less efficiently than in the case of AGC.
(8) The AGU would not respond directly to questions about the climate science town hall.
(9) One neutral and two acidic glycoasparagines were isolated from the urine of patients with aspartylglycosylaminuria (AGU).
(10) The truncated AGU protein was neither catalytically active nor processed into mature alpha and beta subunits.
(11) AGU patients had significantly reduced serum zinc concentrations.
(12) We conclude that the increased serum free dolichol in AGU reflects disturbed lysosomal function and that the decreased free and esterified dolichols in NCLs speak against their presumed primary lysosomal nature.
(13) In aspartylglycosaminuria (AGU), a lysosomal storage disorder of glycoprotein degradation, there are some abnormalities in collagen and proteoglycan metabolism.
(14) 80%) than those linked to a guanosine nucleoside through the same type of bond (AGU, AGG, AGC, ca.
(15) The major known glycosylasparaginase gene defect G488----C, which causes the lysosomal storage disease aspartylglycosaminuria (AGU) in Finland, is located in exon 4.
(16) This bacterium contains two isoacceptor threonine tRNAs having anticodon sequences AGU and UGU, both with unmodified first nucleotides.
(17) We have earlier reported a single missense mutation (Cys163----Ser) to be responsible for 98% of the AGU alleles in the isolated Finnish population, which contains about 90% of the reported AGU patients.
(18) (2) There are two tRNAThr species having anticodons UGU and AGU; the first positions of these anticodons are unmodified.
(19) The altered metabolism in AGU results from a deficiency of the enzyme aspartylglucosaminidase (1-aspartamido-beta-N-acetylglucosamine amidohydrolase), which hydrolyses the asparagine to N-acetylglucosamine linkages of glycoproteins and glycopeptides.
(20) Two base changes were found to be common to all three Finnish AGU patients, a G482----A transition that results in an Arg161----Gln substitution and a G488----C transversion that causes Cys163----Ser.