(a.) Sharp at the end; ending in a sharp point; pointed; -- opposed to blunt or obtuse; as, an acute angle; an acute leaf.
(a.) Having nice discernment; perceiving or using minute distinctions; penetrating; clever; shrewd; -- opposed to dull or stupid; as, an acute observer; acute remarks, or reasoning.
(a.) Having nice or quick sensibility; susceptible to slight impressions; acting keenly on the senses; sharp; keen; intense; as, a man of acute eyesight, hearing, or feeling; acute pain or pleasure.
(a.) High, or shrill, in respect to some other sound; -- opposed to grave or low; as, an acute tone or accent.
(a.) Attended with symptoms of some degree of severity, and coming speedily to a crisis; -- opposed to chronic; as, an acute disease.
(v. t.) To give an acute sound to; as, he acutes his rising inflection too much.
Example Sentences:
(1) In January 2011, the Nobel peace prize laureate was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection .
(2) It is concluded that acute renal denervation augments the pressure diuresis that follows carotid occlusion.
(3) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
(4) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(5) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(7) After a period on fat-rich diet the patient's physical fitness was increased and the recovery period after the acute load was shorter.
(8) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
(9) The results suggest that RPE cannot be used reliably as a surrogate for direct pulse measurement in exercise training of persons with acute dysvascular amputations.
(10) Statistically significant differences were found mainly in the randomized trial, where during the first and second years, respectively, adenoidectomy subjects had 47% and 37% less time with otitis media than control subjects and 28% and 35% fewer suppurative (acute) episodes than control subjects.
(11) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(12) During the procedure, acute respiratory failure developed as a result of tracheal obstruction.
(13) Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case.
(14) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(15) The acute effect of alcohol manifested itself by decreasing mitochondrial respiration, compensated by increased glycolytic activity of the myocardium so that myocardial energy phosphate concentration remained unchanged.
(16) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.
(17) The younger patients more often experienced an acute arthritis with sacroiliitis resembling a reactive disease.
(18) All five individuals appeared to have acute C. pneumoniae infection as determined by results of serologic tests (titers of IgM antibody for all individuals were greater than or equal to 1:16).
(19) The results clearly show that the acute hyperthermia of unrestrained rats induced by either peripheral or central injections of morphine is not caused by activation of the pituitary-adrenal axis.
(20) The effect of hypertension, hyperlipidemia, and the combination of both on acute and chronic myocardial ischemia were evaluated in a total of 30 male rabbits.
Scute
Definition:
(n.) A small shield.
(n.) An old French gold coin of the value of 3s. 4d. sterling, or about 80 cents.
(n.) A bony scale of a reptile or fish; a large horny scale on the leg of a bird, or on the belly of a snake.
Example Sentences:
(1) The number of the long thoracic chaetae of heterozygote females born from crosses between a scute stock and various wild strains can be less than eight.
(2) Immunocytochemical studies demonstrate that the achaete-scute and daughterless genes are required for proper expression of cpo in the PNS but not in other cells that express cpo.
(3) These and other data suggest that the excess function phenotypes of Hw mutations are generated by an increase in achaete or scute transcripts.
(4) Surprisingly, we also find that the level of achaete-scute activity influences the level of hairy expression, thereby providing feedback control upon achaete-scute activity and sensory organ formation.
(5) The scutes were ingested during a period of neglect by the owner.
(6) Although different at their 3' untranslated regions, both cDNAs predict a protein with primary amino acid sequence homology to the previously described amphipathic helix-loop-helix DNA binding and dimerization motif of the Ly1-1, myc, MyoD, immunoglobulin enhancer binding, daughterless, and achaete-scute families of genes.
(7) We have determined the nucleotide sequence of two genes of the achaete - scute complex (AS-C) and show that they are homologous to two previously sequenced members of the same locus.
(8) All three encode a sequence similar to one of the conserved domains of representatives of the vertebrate myc gene family which is also present in the deduced protein sequences of the Drosophila achaete-scute gene complex.
(9) The pro-neural class of genes, for example, the achaete-scute complex, participates in the initial decision to make each uniquely positioned neuroblast or sensory organ, but are initially expressed in groups of cells.
(10) However, replacing the basic region of MyoD with the analogous sequence of other HLH proteins (the immunoglobulin enhancer binding E12 protein or T4 achaete scute protein) allows DNA binding in vitro, yet abolishes muscle-specific gene activation.
(11) The predicted protein product of the lyl-1 gene contains a potential helix-loop-helix DNA binding motif also found in several proteins involved in the control of cellular proliferation and differentiation: all members of the Myc family, MyoD1, myogenin, the Drosophila achaete-scute, twist, and daughterless proteins, and two recently described immunoglobulin enhancer binding proteins.
(12) According to these and previous data, the AS-C is organized, distally to proximally, as follows: the achaete region, with most of its DNA (10 kb) located upstream from the putative achaete (T5) gene; an intermediate region, approximately 18 kb long, whose deletion only weakly affects the scute function; and the scute region, with most of the DNA critical for its function extending 4-5 kb upstream and 50 kb downstream of the putative scute (T4) gene.
(13) Essentially, the double alterations of yellow and scute phenotypes constitute more than 40% of all derivatives.
(14) The achaete-scute T3 and MyoD proteins do not form kappa E2-binding heterodimers together, and no active complex with N-myc was evident.
(15) The achaete and scute mutations lead to reduction of bristles and hairs on head and thorax.
(16) The need for the technique was motivated by a study describing longitudinal growth data from the annuli on abdominal scutes of groups of western painted turtles.
(17) Family selection for directional asymmetry in the expression of the Drosophila melanogaster mutant scute had no result.
(18) The deduced amino acid sequence of clone Myf-5 reveals a region which is highly similar to myc proteins and the developmental factors from Drosophila encoded by the achaete scute locus and the twist gene.
(19) We have confirmed this model by showing that misexpression of the achaete-scute T4 gene induces ectopic Sxl expression and male-specific lethality, confirming that achaete-scute T4 is the sisterless-b counting element.
(20) In the mutants, neuronal precursor cells do not differentiate, suggesting that Hairless might be involved in specifying or realizing neuronal fate in the fly, similar to the 'pro-neural' genes of the achaete-scute complex.