(a.) Sharp at the end; ending in a sharp point; pointed; -- opposed to blunt or obtuse; as, an acute angle; an acute leaf.
(a.) Having nice discernment; perceiving or using minute distinctions; penetrating; clever; shrewd; -- opposed to dull or stupid; as, an acute observer; acute remarks, or reasoning.
(a.) Having nice or quick sensibility; susceptible to slight impressions; acting keenly on the senses; sharp; keen; intense; as, a man of acute eyesight, hearing, or feeling; acute pain or pleasure.
(a.) High, or shrill, in respect to some other sound; -- opposed to grave or low; as, an acute tone or accent.
(a.) Attended with symptoms of some degree of severity, and coming speedily to a crisis; -- opposed to chronic; as, an acute disease.
(v. t.) To give an acute sound to; as, he acutes his rising inflection too much.
Example Sentences:
(1) In January 2011, the Nobel peace prize laureate was admitted to a Johannesburg hospital for what officials initially described as tests but what turned out to be an acute respiratory infection .
(2) It is concluded that acute renal denervation augments the pressure diuresis that follows carotid occlusion.
(3) Ethanol and L-ethionine induce acute steatosis without necrosis, whereas azaserine, carbon tetrachloride, and D-galactosamine are known to produce steatosis with varying degrees of hepatic necrosis.
(4) IgE-mediated acute systemic reactions to penicillin continue to be an important clinical problem.
(5) The cumulative incidence of grade II and III acute GVHD in the 'low dose' cyclosporin group was 42% compared to 51% in the 'standard dose' group (P = 0.60).
(7) After a period on fat-rich diet the patient's physical fitness was increased and the recovery period after the acute load was shorter.
(8) It was concluded that metoclopramide and dexamethasone showed an excellent antiemetic effect on acute drug-induced emesis, as well as on delayed emesis, induced by cisplatin.
(9) The results suggest that RPE cannot be used reliably as a surrogate for direct pulse measurement in exercise training of persons with acute dysvascular amputations.
(10) Statistically significant differences were found mainly in the randomized trial, where during the first and second years, respectively, adenoidectomy subjects had 47% and 37% less time with otitis media than control subjects and 28% and 35% fewer suppurative (acute) episodes than control subjects.
(11) Tumour necrosis factor (TNF), a polypeptide produced by mononuclear phagocytes, has been implicated as an important mediator of inflammatory processes and of clinical manifestations in acute infectious diseases.
(12) During the procedure, acute respiratory failure developed as a result of tracheal obstruction.
(13) Four patients with acute brucellosis are described, none of whom had any connexion with farming or milk industry, the source of infection being different in each case.
(14) The leukemic T-cells in two patients with chronic lymphocytic leukemia (CLL) had specific features of large granular lymphocytes (LGL), and those in two patients with acute lymphocytic leukemia (ALL) had L2 morphologic characteristics.
(15) The acute effect of alcohol manifested itself by decreasing mitochondrial respiration, compensated by increased glycolytic activity of the myocardium so that myocardial energy phosphate concentration remained unchanged.
(16) The introduction of intravenous, high-dose thrombolytic therapy during a brief period has markedly reduced mortality of patients with acute myocardial infarction.
(17) The younger patients more often experienced an acute arthritis with sacroiliitis resembling a reactive disease.
(18) All five individuals appeared to have acute C. pneumoniae infection as determined by results of serologic tests (titers of IgM antibody for all individuals were greater than or equal to 1:16).
(19) The results clearly show that the acute hyperthermia of unrestrained rats induced by either peripheral or central injections of morphine is not caused by activation of the pituitary-adrenal axis.
(20) The effect of hypertension, hyperlipidemia, and the combination of both on acute and chronic myocardial ischemia were evaluated in a total of 30 male rabbits.
Smallpox
Definition:
(n.) A contagious, constitutional, febrile disease characterized by a peculiar eruption; variola. The cutaneous eruption is at first a collection of papules which become vesicles (first flat, subsequently umbilicated) and then pustules, and finally thick crusts which slough after a certain time, often leaving a pit, or scar.
Example Sentences:
(1) A direct fluorescent-antibody test for smallpox is described which utilizes a conjugated antivaccinia serum that was purified by diethylaminoethyl fractionation.
(2) A notable example is percutaneous smallpox vaccination together with the intradermal injection of BCG.
(3) A young girl, vaccinated against smallpox 6 years before suffered from a persistent vaccinia virus infection and a congenital skin disease, i.e.
(4) This would prove the early reactions to be allergic responses of organisms sensitized against smallpox vaccine, capable of stimulating antibody formation.
(5) On the basis of the data obtained PHAT could be recommended as a test for the assessment of the immunological efficacy of the smallpox vaccinations.
(6) Vaccinia-specific antibodies were found in 4 human sera collected 6 weeks after smallpox vaccination.The serological results provide the first laboratory evidence of a monkeypox reservoir in wild monkeys.
(7) The last case of virulent smallpox occurred in Bangladesh in October 1975, and of mild smallpox in Ethiopia in August 1976.
(8) Since May 1980 when the 33rd World Health Assembly declared the global eradication of smallpox, WHO has been developing a comprehensive system of surveillance aimed at maintaining the world permanently free from this disease.
(9) Smallpox victims were estimated at 10-15 million each year, of whom 1.5-2.0 million died.
(10) Five instances of side-effects after oral smallpox immunisation (out of 2568 persons orally immunised) are reported.
(11) In 1796, Edward Jenner developed the first effective vaccine against an infectious disease by using cowpox virus to prevent subsequent infection with smallpox.
(12) Subcutaneous sensitization of guinea pigs with -vaccine, and also an intracardiac injection of smallpox or measles vaccine induced production of brain autoantibodies, whereas subcutaneous or intradermal immunization of the animals with liver viral vaccines was not accompanied by the formation of autoantibodies and development of the pathological processes in the nervous system tissue.
(13) If this is verified, we may say farewell to routine smallpox vaccination.
(14) Useful lessons may be drawn from the successful global Smallpox Eradication Program and applied to the current campaign in the areas of surveillance, strategy, operations, and evaluation.
(15) With this immunization schedule it was possible to obtain smallpox antisera containing precipitins (in a titer of 1:32), hemagglutinins (1:1280), and antibody detectable by the indirect immunofluorescence technique (1:2560).
(16) In sequential serum specimens, the radioimmunoassay test indicated fourfold or greater increases in all of the smallpox patients and in six of eight vaccinated persons.
(17) The obstetric outcome (abortions, stillbirths, prematurity, mature births, and congenital abnormalities) in a group of 1522 consecutive pregnant patients who had smallpox vaccinations during recent pregnancies was compared to that in a similar control group of 2024 consecutive pregnant patients who did not receive any antenatal vaccination.
(18) In this pilot study clinical, electrocardiographic, chemical and immunological findings have been studied during a six weeks' follow-up after routine immunisation (mumps, polio, tetanus, smallpox, diphtheria and type A meningococcal disease) among 234 Finnish conscripts at the beginning of their military service.
(19) The history of smallpox is recounted through the eyes of those who bore witness to its terrors.
(20) All were tuberculin-tested and all had received primary smallpox vaccination but had not been vaccinated with BCG.