(a.) Having lost the power of development, and become rotten, as eggs; putrid. Hence: Unfruitful or confused, as brains; muddled.
(v. t. & i.) To make addle; to grow addle; to muddle; as, he addled his brain.
(v. t. & i.) To earn by labor.
(v. t. & i.) To thrive or grow; to ripen.
Example Sentences:
(1) I also don't particularly want to be reminded of my drug-addled, self-obsessed teenage antics.
(2) I just don’t know, but at least every time I hear this great piece of music I can picture all this and more in my tiny drug-addled mind.
(3) In a sense, the ABB's petition is encouraging, since it suggests that eight years mainlining easy cash has addled their brains.
(4) If the automatic budget cuts are a brick wall, the Democrats and Republicans are the addled maniacs fighting for control of the wheel as they drive straight for it.
(5) But I find myself too addled by the fact of Hamm's handsomeness, and also his celebrity, to make much sense.
(6) It even becomes, in the mind of some of its more addled fanatics, a universal language.
(7) Cracked Actor – Alan Yentob’s BBC documentary of the 1974 US tour, revealing a frail, coke-addled Bowie on the edge of dissolution, as weird and remote as his role in The Man Who Fell to Earth – was very much the exception.
(8) With his contortionist’s body, vulnerability, pale skin and fierce red hair, he didn’t suit the classical white ballets; it took the visceral, addled heroes of Kenneth MacMillan and new, abstract choreographers to turn him into a star.
(9) MacFarlane was also recently in trouble after hosting a televised comedy "roasting" of the drug and drink-addled Charlie Sheen that played relentlessly on the cruel notion that the actor would soon be dead.
(10) They come with a reputation, built on a drug-addled lifestyle and wild, willy-waving gigs.
(11) In fact, he says, "it was all a drug-addled circus and journalists who also knew that were part of the fraud, reporting on the cyclists as if they were heroes when they knew they were not".
(12) House speaker John Boehner to resign after battle with conservatives Read more It was fitting because, over the past five years, Boehner himself has presided over a far less decorous and infinitely more fractious show of ardent faith, as the House Republican majority has been inundated with true believers in the government-hating, austerity-addled Tea Party gospel.
(13) The news led me to wonder whether Lidl's appeal now extends beyond cherry-addled teenagers and to that holy grail of the advertising executive, the ordinary family.
(14) The mass killing of Afghan civilians by a US soldier in Kandahar was a shocking reminder of an enduring truth of this decade-old conflict: the efforts of thousands of people over many years at a cost of billions can be undone in a few seconds by the actions of a single, hate-addled individual.
(15) The freewheeling optimism of the 1960s had given way to the drug-addled reality of the 1970s and they were battered and bruised from 16 years on the road.
(16) Inherent Vice is the story of drug-addled Larry "Doc" Sportello, a private detective who gets pulled into a murder investigation after taking on a case from an ex-girlfriend.
(17) Is it, as Franzen and the others fear, turning kids into emoticon-addled zombies, unable to connect, unable to think, form a coherent thought or even make eye contact?
(18) Facebook Twitter Pinterest As much as Hologram Tupac undoubtedly blew the festival-addled minds of Coachella attendees on Sunday, there was also a sense of inevitability about it.
(19) It is feasible too that Frey's booze-soaked, crack-addled brain did remember events differently from the way they occurred; after all, a large section of his life exists like a half-remembered drunken night out.
(20) Colin Welland's great fat arse and great shorts addling, sploshing through mud, making aeroplane noises, and chewing on an apple, and I thought, oh, you know, it's going to be one of those dire, dread embarrassments, because it ain't gonna work.
Dregs
Definition:
Example Sentences:
(1) Receptors known as DREG adhesion molecules on human neutrophils and monocytes provide for homing of these phagocytic leukocytes to sites of inflammation.
(2) Finally, all five DREG mAbs specifically stain COS cells transfected with LAM-1 cDNA, a putative human homologue of mouse MEL-14 antigen.
(3) Perhaps set smaller goals to begin with, for instance "Don't drink the dregs of strangers' drinks" or "No drinking on your own in the morning in a toilet cubicle at work", and see where you go from there.
(4) We studied its expression on eosinophils using flow cytometry and the MAb Dreg-56 and Leu-8.
(5) While the fourth seeded Bulls’ 35-29 record is something of a mirage, as they have faced the dregs of the Eastern Conference, that doesn’t take away from the fact this team was expected to be one of those dregs after Rose injured himself and Deng was traded.
(6) Accumulation of DREG-negative monocytes in association with sepsis may be sufficient to impair their recruitment to inflammatory sites and limit their contribution to host defense against infection and tissue repair.
(7) From the depraved dregs of humanity; the glorious blossoming of hope, a tangible act of togetherness; the salvation of pop.
(8) "If you think that in this country another person can be found who would create such a structure, who would drag into this work all the dregs of the provincial towns, who would make provincial shits into princesses of the capital, then fuck off.
(9) 5.15pm, and I'm harbouring serious reservations about the mental well-being of Guardian Unlimited Football's readership: "I am sitting alone in my serviced apartment in Singapore, wearing a Scotland top and boxer shorts like a Caledonian David Mellor, nursing the dregs of my one and only can of Tiger," writes Neil Cocker, in what can only be a cry for help.
(10) It's important to remember that Clearing isn't the dregs of the barrel," says Claire Chalmers, student recruitment officer at Goldsmiths, University of London.
(11) The DREG antibodies offer powerful tools for analyzing the role of homing receptors in human neutrophil-endothelial cell interactions, and also may prove valuable in the clinical assessment of neutrophil activation.
(12) The US, Canadian and Australian governments have chased the CCS dream with zeal, often using its compressed CO2 byproduct to prise away tar sands and eke out the dregs of depleted fossil fuel reserves.
(13) Moreover, mAb DREG-56 significantly diminished adhesion of healthy adult but not cord blood suspensions in the presence or absence of the anti-CD18 mAb R15.7.
(14) The DREG-56 mAb specifically inhibits greater than 90% of binding of human lymphocytes to HEVs within frozen sections of peripheral but not mucosal lymphoid tissue.
(15) These results demonstrate that the DREG mAbs define a human lymphocyte homing receptor for PLN HEVs and indicate that this human antigen is homologous to the MEL-14-defined murine lymphocyte homing receptor.
(16) That’s the only thing they understand.” Donald Trump’s presidential campaign energized and reanimated various pockets of far-rightwing America, from the dregs of the Ku Klux Klan represented by David Duke to the seemingly ascendant “alt-right”, members of which gathered in Washington DC after the election at a “thinktank” conference that saw audience members participate in Nazi salutes.
(17) These results suggest that monocytes are more affected than neutrophils in vivo by conditions expected to stimulate shedding of DREG and that sepsis promotes shedding of these adherence receptors.
(18) To test this hypothesis, we have analyzed the expression of DREG receptors on neutrophils and monocytes from 25 patients admitted to the Surgical Intensive Care Unit.
(19) For 14 nonseptic patients, mean monocyte positivity for DREG was reduced from 64% to 40%.
(20) One Love Manchester: pop's healing power rises from the dregs of depravity | Hannah Jane Parkinson Read more Some of the victims’ families had bristled at Grande hosting the concert so soon after the suicide bombing that killed 22 people , but her earnestness and emotional acuity meant that for thousands of people, this was an event that soothed and uplifted.