(v. t.) To draw towards a common center or a middle line.
Example Sentences:
(1) Chromatographic maps of DNA adducts demonstrated unique patterns of DNA adducts for each of the regions.
(2) Substances with a leaving group at the C-3 position form unsaturated conjugated cyclic adducts and are mutagenic only in the His D3052 frameshift strains with an intact excision repair system (no urvA mutation).
(3) elution patterns of the adducts formed by DBF metabolites with DNA and obtained in vivo at the optimal exposure time of 42-48 h were qualitatively very similar to the patterns obtained in vitro, but their amplitude was quantitatively reduced.
(4) The spectrum of one of these species ressembles that of a N(5)-C(4a) dihydroflavin adduct.
(5) The bacterial strains did not liberate free patulin from the adduct mixture present in the growth medium.
(6) It is possible that serum transport is an important source of carcinogenic metabolite and results in DNA adduct formation in tissues.
(7) tert-Butyl hydroaminoxyl is detected as a degradation product of the hydroxyl adduct from all spin traps.
(8) No significant quantitative differences in AFB1-DNA adduct formation between the dietary groups were observed following the first exposure to [3H]AFB1; however, total aflatoxin-DNA adduct levels in the choline-deficient animals were significantly increased during the multiple dose schedule.
(9) Aromatic adducts present in the digest that were resistant to nuclease P1 were thus 32P-labelled while unmodified nucleotides were not.
(10) The alkenylbenzenes, safrole and methyleugenol, also formed DNA adducts detectable by this method.
(11) For dipeptides containing the amino terminal residues glycine, alanine and phenylalanine, abstraction of the hydrogen from the carbon adjacent to the peptide nitrogen was the major process leading to the spin-adducts.
(12) This review is primarily focussed on the application of immunoassays and 32P-postlabeling for human DNA adduct monitoring.
(13) The adduct levels in the local controls were substantially higher than those in the countryside controls.
(14) The sites for replication stoppage as well as the lack of a Mn2+ effect on adducted templates have implications for the mechanisms of mutagenesis by activated AFB1.
(15) The K-region oxides bound directly to DNA to give adducts similar to the minor products detected in the microsomal incubations.
(16) Duane's retraction syndrome is a congenital eye movement disorder characterized by a deficiency of abduction, mild limitation of adduction, with retraction and narrowing of the palpebral fissure on attempted adduction.
(17) Therefore, 2-AF:DNA adducts can be used as a differential end point with which to assess the relative roles of N-hydroxylation and peroxidation in the metabolic activation of 2-AF in cell culture and in target tissues in vivo.
(18) In the case of adducts with the diol-epoxides of benzo[c]phenanthrene, the energetically most favored structures are isomers with significant biological activity.
(19) Also, sodium borohydride reduction of the cDNA and PEI-HRP adduct crosslinked by the glutardialdehyde resulted in the stabilization of the probes.
(20) To determine whether the same bioactivation process occurs in whole animals, 3MI was administered to goats, mice, and rats, and the urinary metabolites from these three species were analyzed by HPLC for the presence of the mercapturate that would be expected as the processed and excreted form of the 3MI-glutathione adduct.
Laden
Definition:
(p. & a.) Loaded; freighted; burdened; as, a laden vessel; a laden heart.
Example Sentences:
(1) We conclude that: 1) the effective capillary PO2 in the fetal brain can be significantly reduced by increasing the distance between non-methemoglobin-laden erythrocytes in capillaries and 2) hypoxic inhibition of fetal breathing probably arises from discrete areas of the brain having a PO2 less than 3 Torr.
(2) Histologically, 3-week explants showed only small areas of neointima with myofibroblasts and endothelial cells; the outer capsules were infiltrated by lipid-laden macrophages.
(3) The day it opened in the US, three senators – senate select committee on intelligence chairwoman Dianne Feinstein, Carl Levin and John McCain – released a letter of protest to Sony Pictures's CEO, citing their committee's 6,000-page classified report on interrogation tactics and calling on him "to state that the role of torture in the hunt for Osama bin Laden is not based on the facts, but rather part of the film's fictional narrative".
(4) The doom-laden voiceover claims Miliband could only secure power through a deal with the SNP and that Salmond would be able to “call the tune”.
(5) Contraction of the cell-laden gel occurred subsequently to create a new zone in the cell chamber.
(6) The debris-laden macrophages appear to migrate from the tail to the body.
(7) All organs took up 67Cu from both sources, but there was a tendency for increased uptakes in copper-deficient rats and decreased uptake in copper-laden rats.
(8) By light microscopy they contained lipid-laden cells (oil red O and Sudan black B positive), collagen, and much acid mucopolysaccharide.
(9) Yemen has long been the base of al-Qaida in the Arabian Peninsula, an offshoot of Osama bin Laden’s original group that has previously targeted Houthis.
(10) There is a perfectly illogical explanation for it; polio drops are meant to make us impotent and these programmes are run by the same people who managed to locate Osama bin Laden by running another scam vaccination campaign.
(11) I personally want to know how they caught bin Laden.
(12) The association of neutral fat-laden cells with the increase in lecithin could be due to a common origin from the skin of the fetus.
(13) Bin Laden himself headed north into the remote Afghan province of Kunar after the battle of Tora Bora in December 2001.
(14) Sure enough, the rowdy crowd in the Fox News audience gave him a lusty boo - the loudest of a rambunctious night and maybe of the entire primary season so far - while Gingrich called him "utterly irrational" for questioning the manner of Bin Laden's killing.
(15) In the letter, Gadahn – who the White House has announced was killed in a US drone stike in January – told the al-Qaida leader that Benjamin Franklin had never been a president of the United States and warned that if he or Ayman al-Zawahiri, Bin Laden’s deputy, made the mistake in propaganda speeches, their credibility would suffer.
(16) At least two of Bin Laden's sons – Hamza and Saad – apparently followed him into radicalism.
(17) In an attempt to reveal the role of antigen-laden marginal metallophil (MM) and other macrophages in the intrasplenic immune response of a specific B-cell lineage to a thymus-independent type-2 antigen (Ficoll conjugated with fluorescein isothiocyanate), simultaneous immunohistological observations of the involved cells were performed in the rat.
(18) The Associated Press quoted a US security source as saying the Somali raid was carried out by members of the same navy Seal team that killed the al-Qaida founder Osama bin Laden.
(19) Nurses' responses were more personalized and affect-laden.
(20) Bin Laden, who was 54 when he died, also had a copy of The America I Have Seen, a vitriolic memoir of a short trip to the US by the Egyptian thinker and activist Syed Qutb , considered the godfather of modern jihadi thinking and hanged in 1966.