(1) Although there are no definite data on increased activity with the addition of cyclophosphamide (CTX) and vincristine (VCR) to ADIC, we prefer CYVADIC because of the higher reported complete response rate.
(2) Toxicity due to ADIC treatment was acceptable and did not exceed that seen when doxorubicin was given as a single agent.
(3) It is concluded that serum complement is consumed as part of the multisystem dysfunction, aDIC, and that in conjunction with traditional indicators it may be utilized to gauge the severity of this syndrome.
(4) Complement component C3, component C4, and total hemolytic complement CH50 were measured in blood from ten patients with acute disseminated intravascular coagulation (aDIC) syndromes.
(5) The five dogs having complete responses to the first ADIC treatment had a median survival time of 105 days (range, 45-241 days) after this treatment.
(6) Five of the 15 dogs had a complete response to the first treatment with ADIC, and three had partial responses.
(7) This medium, called GAMA, contains as its relevant constituents the following: the purines guanine and adenine and the purine biosynthetic pathway inhibitors mycophenolic adic, which blocks conversion of adenine ribonucleotides to guanine ribonucleotides, and azaserine, which blocks de novo purine synthesis.
(8) ADIC is apparently a useful chemotherapeutic combination to reinduce remission in some dogs with relapsed lymphoma.
(9) One dog that received a third ADIC treatment no longer responded.
(10) Cardiovascular disease occupy a major place among the adication required to disqualify pilots due to visceral injuries.
(11) The median survival time from the first ADIC treatment for all dogs was 45 days (range, 18-241 days).
(12) Human diploid fibroblast cultures induced to make interferon by the combination of polyriboinosinic acid-polyribocytidylic adic, cycloheximide and actinomycin D degenerate thereafter, owing to the irreversible nature of the inhibition induced by actinomycin D. However, cultures superinduced with the DNA-dependent RNA synthesis inhibitor 5,6-dichloro-I-beta-D-ribofuranosylbenzimadazole (DRB) survive, owing to the reversible nature of the inhibition induced by DRB, and can again be superinduced on several occasions.
(13) The addition of methotrexate did not improve the response rate when compared with our previous CYV ADIC protocol.
(14) Fifteen dogs with relapsed lymphoma were treated with doxorubicin and dacarbazine (ADIC) to reinduce remission.
(15) In combination chemotherapy ADIC and CYVADIC are probably the best choice.
Function
Definition:
(n.) The act of executing or performing any duty, office, or calling; per formance.
(n.) The appropriate action of any special organ or part of an animal or vegetable organism; as, the function of the heart or the limbs; the function of leaves, sap, roots, etc.; life is the sum of the functions of the various organs and parts of the body.
(n.) The natural or assigned action of any power or faculty, as of the soul, or of the intellect; the exertion of an energy of some determinate kind.
(n.) The course of action which peculiarly pertains to any public officer in church or state; the activity appropriate to any business or profession.
(n.) A quantity so connected with another quantity, that if any alteration be made in the latter there will be a consequent alteration in the former. Each quantity is said to be a function of the other. Thus, the circumference of a circle is a function of the diameter. If x be a symbol to which different numerical values can be assigned, such expressions as x2, 3x, Log. x, and Sin. x, are all functions of x.
(v. i.) Alt. of Functionate
Example Sentences:
(1) Activity of Na,K-ATPase activity was measured as a functional marker for synaptosomal membranes.
(2) Herpesviruses such as EBV, HSV, and human herpes virus-6 (HHV-6) have a marked tropism for cells of the immune system and therefore infection by these viruses may result in alterations of immune functions, leading at times to a state of immunosuppression.
(3) Among the pathological or abnormal ECGs (25.6%) prevailed the vegetative-functional heart diseases with 92%.
(4) The influence of the various concepts for the induction of lateral structure formation in lipid membranes on integral functional units like ionophores is demonstrated by analysing the single channel current fluctuations of gramicidin in bimolecular lipid membranes.
(5) We also show that proliferation of primary amnion cells is not dependent on a high c-fos expression, suggesting that the function of c-fos is more likely to be associated with other cellular functions in the differentiated amnion cell.
(6) Elements in the skin therefore seemed to enhance nerve regeneration and function.
(7) The possibility that the ventral nerve photoreceptor cells serve a neurosecretory function in the adult Limulus is discussed.
(8) Renal micropuncture and microdissection techniques with ultramicro fluid analysis have been applied to evaluate single nephron function in the skate, Raja erinacea.
(9) We have amended and added to Fabian's tables giving a functional assessment of individual masticatory muscles.
(10) Models able to describe the events of cellular growth and division and the dynamics of cell populations are useful for the understanding of functional control mechanisms and for the theoretical support for automated analysis of flow cytometric data and of cell volume distributions.
(11) Tests showed the cells survive and function normally in animals and reverse movement problems caused by Parkinson's in monkeys.
(12) Subsequently, the study of bundle branch block and A-V block cases revealed that no explicit correlation existed between histopathological changes and functional disturbances nor between disturbances in conduction (i.e.
(13) We have examined the insertion of bovine 17 alpha-hydroxylase (P45017 alpha) into the endoplasmic reticulum of COS 1 cells to evaluate the functional role of its hydrophobic amino-terminal sequence and membrane insertion.
(14) We sought additional evidence for an inverse relationship between functional CTL-target cell affinity on the one hand, and susceptibility of the CTL-mediated killing to inhibition by alpha LFA-1 and alpha Lyt-2,3 monoclonal antibodies on the other hand.
(15) The 14C-aminopyrine breath test was used to measure liver function in 14 normal subjects, 16 patients with alcoholic cirrhosis, 14 alcoholics without cirrhosis, and 29 patients taking a variety of drugs.
(16) The strongest predictor of non-sudden cardiac death was the New York Heart Association functional class.
(17) We maximize an objective function that includes both total production rate and product concentration.
(18) Hypertensive disorders in pregnancy are frequently accompanied by deteriorated renal functions and by pathological lesions in the glomeruli.
(19) Based on several previous studies, which demonstrated that sorbitol accumulation in human red blood cells (RBCs) was a function of ambient glucose concentrations, either in vitro or in vivo, our investigations were conducted to determine if RBC sorbitol accumulation would correlate with sorbitol accumulation in lens and nerve tissue of diabetic rats; the effect of sorbinil in reducing sorbitol levels in lens and nerve tissue of diabetic rats would be reflected by changes in RBC sorbitol; and sorbinil would reduce RBC sorbitol in diabetic man.
(20) However, the relationships between sociometric status and social perception varied as a function of task.