(1) Although there are no definite data on increased activity with the addition of cyclophosphamide (CTX) and vincristine (VCR) to ADIC, we prefer CYVADIC because of the higher reported complete response rate.
(2) Toxicity due to ADIC treatment was acceptable and did not exceed that seen when doxorubicin was given as a single agent.
(3) It is concluded that serum complement is consumed as part of the multisystem dysfunction, aDIC, and that in conjunction with traditional indicators it may be utilized to gauge the severity of this syndrome.
(4) Complement component C3, component C4, and total hemolytic complement CH50 were measured in blood from ten patients with acute disseminated intravascular coagulation (aDIC) syndromes.
(5) The five dogs having complete responses to the first ADIC treatment had a median survival time of 105 days (range, 45-241 days) after this treatment.
(6) Five of the 15 dogs had a complete response to the first treatment with ADIC, and three had partial responses.
(7) This medium, called GAMA, contains as its relevant constituents the following: the purines guanine and adenine and the purine biosynthetic pathway inhibitors mycophenolic adic, which blocks conversion of adenine ribonucleotides to guanine ribonucleotides, and azaserine, which blocks de novo purine synthesis.
(8) ADIC is apparently a useful chemotherapeutic combination to reinduce remission in some dogs with relapsed lymphoma.
(9) One dog that received a third ADIC treatment no longer responded.
(10) Cardiovascular disease occupy a major place among the adication required to disqualify pilots due to visceral injuries.
(11) The median survival time from the first ADIC treatment for all dogs was 45 days (range, 18-241 days).
(12) Human diploid fibroblast cultures induced to make interferon by the combination of polyriboinosinic acid-polyribocytidylic adic, cycloheximide and actinomycin D degenerate thereafter, owing to the irreversible nature of the inhibition induced by actinomycin D. However, cultures superinduced with the DNA-dependent RNA synthesis inhibitor 5,6-dichloro-I-beta-D-ribofuranosylbenzimadazole (DRB) survive, owing to the reversible nature of the inhibition induced by DRB, and can again be superinduced on several occasions.
(13) The addition of methotrexate did not improve the response rate when compared with our previous CYV ADIC protocol.
(14) Fifteen dogs with relapsed lymphoma were treated with doxorubicin and dacarbazine (ADIC) to reinduce remission.
(15) In combination chemotherapy ADIC and CYVADIC are probably the best choice.
Rank
Definition:
(superl.) Luxuriant in growth; of vigorous growth; exuberant; grown to immoderate height; as, rank grass; rank weeds.
(superl.) Raised to a high degree; violent; extreme; gross; utter; as, rank heresy.
(superl.) Causing vigorous growth; producing luxuriantly; very rich and fertile; as, rank land.
(superl.) Strong-scented; rancid; musty; as, oil of a rank smell; rank-smelling rue.
(superl.) Strong to the taste.
(superl.) Inflamed with venereal appetite.
(adv.) Rankly; stoutly; violently.
(n. & v.) A row or line; a range; an order; a tier; as, a rank of osiers.
(n. & v.) A line of soldiers ranged side by side; -- opposed to file. See 1st File, 1 (a).
(n. & v.) Grade of official standing, as in the army, navy, or nobility; as, the rank of general; the rank of admiral.
(n. & v.) An aggregate of individuals classed together; a permanent social class; an order; a division; as, ranks and orders of men; the highest and the lowest ranks of men, or of other intelligent beings.
(n. & v.) Degree of dignity, eminence, or excellence; position in civil or social life; station; degree; grade; as, a writer of the first rank; a lawyer of high rank.
(n. & v.) Elevated grade or standing; high degree; high social position; distinction; eminence; as, a man of rank.
(v. t.) To place abreast, or in a line.
(v. t.) To range in a particular class, order, or division; to class; also, to dispose methodically; to place in suitable classes or order; to classify.
(v. t.) To take rank of; to outrank.
(v. i.) To be ranged; to be set or disposed, as in a particular degree, class, order, or division.
(v. i.) To have a certain grade or degree of elevation in the orders of civil or military life; to have a certain degree of esteem or consideration; as, he ranks with the first class of poets; he ranks high in public estimation.
Example Sentences:
(1) Treatment termination due to lack of efficacy or combined insufficient therapeutic response and toxicity proved to be influenced by the initial disease activity and by the rank order of prescription.
(2) Despite a 10-year deadline to have the same number of ethnic minority officers in the ranks as in the populations they serve, the target was missed and police are thousands of officers short.
(3) Measures of average and cumulative rank were used to augment tests of the significance of correlations between different indicators.
(4) The programs are written in Fortran and are implemented on a Rank Xerox Sigma 6 computer.
(5) Significant differences in the pharmacological characteristics of the alpha 2 adrenoceptor were observed between the tissues with reference to both absolute drug affinities as well as rank order of drug potency.
(6) While superheroes like “superman” (21st in SplashData’s 2014 rankings) and “batman” (24th) may be popular choices for passwords, the results if they are cracked could be anything other than super – and users will only have themselves to blame.
(7) This analysis is based on a ranking of neighbourhoods according to the participation of young people in higher education.
(8) When histamine (5 micrograms) was injected into three different levels of the ventricular system, the magnitude and duration of the resulting increases in plasma epinephrine and glucose were in the following rank order: the third ventricle greater than aqueduct much greater than fourth ventricle.
(9) The rank order of potency of the peptides tested was VIP greater than rat (r) peptide histidine isoleucine = human (h) PHI greater than rGRF greater than bovine GRF = porcine PHI = VIP-(10-28) greater than hGRF greater than secretin greater than apamin greater than glucagon.
(10) In the latter case, the studies have resulted in a ranking of processes and treatment methods to protect the environment.
(11) Cefuzoname seems to be among the middle ranks of beta-lactam agents as far as penetration rate is concerned; however, when its potent antibacterial activity and broad spectrum are taken into account, the concentrations in CSF in patients with meningitis seem worth examining.
(12) They include two leading Republican hopefuls for the presidential race in 2016, Rand Paul and Marco Rubio; three of them enjoy A+ rankings from the NRA and a further eight are listed A. Rand Paul of Kentucky The junior senator's penchant for filibusters became famous during his nearly 13-hour speech against the use unmanned drones, and he is one of three senators who sent an initial missive to Reid , warning him of another verbose round.
(13) Using an explicit process, the Oregon Health Services Commission has completed the ranking of 714 condition-treatment pairs.
(14) Autonomy, sense of accomplishment and time spent in patient care ranked as the top three factors contributing to job satisfaction.
(15) On guinea-pig lung strip the rank order of potency was U-46619 greater than Wy17186 much greater than PGF2 alpha greater than PGE2 and responses to all agonists tested were blocked by AH19437 but not by SC-19220.
(16) In the UK, George Osborne used this to his advantage, claiming "Britain faces the disaster of having its international credit rating downgraded" even after Moody's ranked UK debt as "resilient".
(17) The eight senators, including the incoming ranking member Mark Warner of Virginia, wrote to Barack Obama to request he declassify relevant intelligence on the election.
(18) Hence, a priori haplotyping cannot exclude a particular CF mutation, but in combination with population genetic data, enables mutations to be ranked by decreasing probability.
(19) The rank order of potencies of the four AEDs was: (a) in young: CBZ > PHT > PhB > VPA; (b) in adult: CBZ > PhB > PHT > VPA.
(20) Patients clinically evaluated as effective tended to be so pathologically as well, as shown by Spearman's rank correlation test which gave a significant correlation between the clinical and pathological scores.